Results 61 to 70 of about 1,739,773 (346)

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]

, 2003
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E, Gillespie, SH, Gosling, RD, Kanduma, EG, Morris, RW, Nyindo, M, Sam, NE, Uiso, LO   +7 more
core   +1 more source

Delay in diagnosis of pulmonary tuberculosis in low-and middle-income settings: systematic review and meta-analysis

BMC Pulmonary Medicine, 2017
BackgroundAssessment of delays in seeking care and diagnosis of tuberculosis is essential to evaluate effectiveness of tuberculosis control programs, and identify programmatic impediments.
F. Getnet, M. Demissie, N. Assefa, B. Mengistie, A. Worku   +4 more
semanticscholar   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Pulmonary tuberculosis and some underlying conditions in Golestan Province of Iran, during 2001-2005 [PDF]

, 2009
Context: Pulmonary tuberculosis has been a major health problem in Golestan province of Iran. Aims: This descriptive cross-sectional study was performed to evaluate the frequency of coexisting medical conditions and their effects on some epidemiologic ...
Dashti, M., Golsha, R., Najafi, L., Rezaei, S.R., Roshandel, G., Shafiee, A.   +5 more
core  

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
A. Roderick Escombe, Alland, Armando Gonzalez, Balasubramanian, Beggs, Behr, Bock, Bonnet, Borgdorff, Burgos, Calder, Capewell, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine J Noakes, Caviedes, Caviedes, Cox, Cruciani, David A. J Moore, Desjardin, Eduardo Ticona, Escombe, Escombe, Escombe, Espinal, Fennelly, Fennelly, Gandhi, Garcí, Jindani, Jon S Friedland, Kamerbeek, Loudon, Luz Caviedes, Malasky, Marcos Navincopa, Nardell, Palmero, Patricia Sheen, Peter Wilson, Riley, Riley, Riley, Robert H Gilman, Rose, Rouillon, Shamputa, Snider, Sultan, Teixeira, van Soolingen, William Pan   +53 more
core   +7 more sources

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

The Pediatric Infectious Disease Journal, 2018
We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same
M. Nicol, L. Workman, M. Prins, L. Bateman, Yonas Ghebrekristos, Silindile Mbhele, C. Denkinger, H. Zar   +7 more
semanticscholar   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

Nature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng, Yuanna Cheng, Mingtong Ma, Qiu Chen, Yongjia Duan, Shanshan Liu, Hongyu Cheng, Hua Yang, Jingping Huang, Wenyi Bu, Chenyue Shi, Xiangyang Wu, Jianxia Chen, Ruijuan Zheng, Zhonghua Liu, Zhe Ji, Jie Wang, Xiaochen Huang, Peng Wang, Wei Sha, Baoxue Ge, Lin Wang   +21 more
doaj   +1 more source

Exhaled Nitric Oxide is Not a Biomarker for Pulmonary Tuberculosis. [PDF]

, 2018
To reduce transmission of tuberculosis (TB) in resource-limited countries where TB remains a major cause of mortality, novel diagnostic tools are urgently needed.
Aston, Barnes, Chan, Daniel Pastorius, Daniel Smith, Dweik, Eduardo Ticona, Elmasri, Idh, Jon S. Friedland, José W. López, Karina M. Romero, Kim, Lim, Luz Caviedes, Maria-Cristina I. Loader, Marjory Bravard, Moore, Olin, O’Garra, Ralph, Ralph, Robert H. Gilman, Schon, Taryn Clark, Van Beek, Wang, William Checkley, Yhi   +28 more
core   +1 more source

Alternation of Gut Microbiota in Patients with Pulmonary Tuberculosis

Frontiers in Physiology, 2017
One-third of the world's population has been infected with Mycobacterium tuberculosis (M. tuberculosis), a primary pathogen of the mammalian respiratory system, while about 10% of latent infections progress to active tuberculosis (TB), indicating that ...
Mei Luo, Yong Liu, Pengfei Wu, D. Luo, Qun Sun, Han Zheng, Richard Hu, S. Pandol, Qingfeng Li, Yuanping Han, Yilan Zeng   +10 more
semanticscholar   +1 more source