Results 61 to 70 of about 1,747,294 (351)

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
A. Roderick Escombe, Alland, Armando Gonzalez, Balasubramanian, Beggs, Behr, Bock, Bonnet, Borgdorff, Burgos, Calder, Capewell, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine J Noakes, Caviedes, Caviedes, Cox, Cruciani, David A. J Moore, Desjardin, Eduardo Ticona, Escombe, Escombe, Escombe, Espinal, Fennelly, Fennelly, Gandhi, Garcí, Jindani, Jon S Friedland, Kamerbeek, Loudon, Luz Caviedes, Malasky, Marcos Navincopa, Nardell, Palmero, Patricia Sheen, Peter Wilson, Riley, Riley, Riley, Robert H Gilman, Rose, Rouillon, Shamputa, Snider, Sultan, Teixeira, van Soolingen, William Pan   +53 more
core   +7 more sources

Development and Validation of a Deep Learning–based Automatic Detection Algorithm for Active Pulmonary Tuberculosis on Chest Radiographs

Clinical Infectious Diseases, 2018
Background Detection of active pulmonary tuberculosis on chest radiographs (CRs) is critical for the diagnosis and screening of tuberculosis. An automated system may help streamline the tuberculosis screening process and improve diagnostic performance ...
Eui Jin Hwang, Sunggyun Park, K. Jin, Jung Im Kim, So Young Choi, Jong Hyuk Lee, J. Goo, Jaehong Aum, J. Yim, C. Park, Dong Hyeon Woo Choi In Pyung Yong Sub Lim Kim Jae Yeon Kim Woo Choi Hwang Song Lim Kim Wi Oh Kang, Dong Hyeon Kim, Woo Woo, C. Choi, I. Hwang, Y. Song, Lim Lim, K. Kim, J. Wi, Su Suk Oh, Mi-Jin Kang   +20 more
semanticscholar   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

Nature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng, Yuanna Cheng, Mingtong Ma, Qiu Chen, Yongjia Duan, Shanshan Liu, Hongyu Cheng, Hua Yang, Jingping Huang, Wenyi Bu, Chenyue Shi, Xiangyang Wu, Jianxia Chen, Ruijuan Zheng, Zhonghua Liu, Zhe Ji, Jie Wang, Xiaochen Huang, Peng Wang, Wei Sha, Baoxue Ge, Lin Wang   +21 more
doaj   +1 more source

Pulmonary tuberculosis and some underlying conditions in Golestan Province of Iran, during 2001-2005 [PDF]

, 2009
Context: Pulmonary tuberculosis has been a major health problem in Golestan province of Iran. Aims: This descriptive cross-sectional study was performed to evaluate the frequency of coexisting medical conditions and their effects on some epidemiologic ...
Dashti, M., Golsha, R., Najafi, L., Rezaei, S.R., Roshandel, G., Shafiee, A.   +5 more
core  

Exhaled Nitric Oxide is Not a Biomarker for Pulmonary Tuberculosis. [PDF]

, 2018
To reduce transmission of tuberculosis (TB) in resource-limited countries where TB remains a major cause of mortality, novel diagnostic tools are urgently needed.
Aston, Barnes, Chan, Daniel Pastorius, Daniel Smith, Dweik, Eduardo Ticona, Elmasri, Idh, Jon S. Friedland, José W. López, Karina M. Romero, Kim, Lim, Luz Caviedes, Maria-Cristina I. Loader, Marjory Bravard, Moore, Olin, O’Garra, Ralph, Ralph, Robert H. Gilman, Schon, Taryn Clark, Van Beek, Wang, William Checkley, Yhi   +28 more
core   +1 more source

Delay in diagnosis of pulmonary tuberculosis in low-and middle-income settings: systematic review and meta-analysis

BMC Pulmonary Medicine, 2017
BackgroundAssessment of delays in seeking care and diagnosis of tuberculosis is essential to evaluate effectiveness of tuberculosis control programs, and identify programmatic impediments.
F. Getnet, M. Demissie, N. Assefa, Bizatu Mengistie, A. Worku   +4 more
semanticscholar   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Current landscape of exosomes in tuberculosis development, diagnosis, and treatment applications

Frontiers in Immunology
Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (MTB), remains one of the most prevalent and deadly infectious diseases worldwide. Currently, there are complex interactions between host cells and pathogens in TB. The onset,
Xuezhi Sun, Wei Li, Li Zhao, Ke Fan, Fenfen Qin, Liwen Shi, Feng Gao, Chunlan Zheng   +7 more
doaj   +1 more source