Results 171 to 180 of about 1,231,953 (350)

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Non-TNF-targeted drugs in rheumatic diseasescombined with latent tuberculosis infection. [PDF]

Clin Exp Med
Xiang Z, Liuyu, Zou H.
europepmc   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Heterogeneity in tuberculosis

Nature reviews. Immunology, 2017
Anthony M. Cadena, S. Fortune, J. Flynn
semanticscholar   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Tuberculosis: Clinical Laboratory Diagnostic Techniques and Future Perspectives. [PDF]

Vaccines (Basel)
Song Q, Liu J, Wang C.
europepmc   +1 more source

SOME UNUSUAL MANIFESTATIONS OF TUBERCULOSIS.

, 1934
Humphry Rolleston
openalex   +1 more source

Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

FEMS Microbiology Reviews, 2017
Sebastian M. Gygli, S. Borrell, Andrej Trauner, S. Gagneux   +3 more
semanticscholar   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

Mathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang, Yaya Wang, Hongyin Geng, Wei Gao, Esin Ilhan, Haci Mehmet Baskonus   +5 more
wiley   +1 more source