Results 41 to 50 of about 1,153,912 (357)

Antibodies and tuberculosis

Tuberculosis, 2016
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development
Gavin R. Screaton, Robert J. Wilkinson, Ashley Jacobs, Ashley Jacobs, Juthathip Mongkolsapaya, Helen McShane   +5 more
openaire   +5 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim, You‐Ri Kang, Jae‐Won Hyun, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS

Туберкулез и болезни лёгких, 2016
Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients ...
L. A. Popova, E. A. Shergina, O. V. Lovacheva, T. R. Bagdasaryan, N. A. Chernykh, V. B. Nefedov   +5 more
doaj   +1 more source

Reduction of the risk of bronchopleural complications after pneumonectomy due to the use of intraoperative laser treatment of the stump of the main bronchus

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Purpose of the study: due to the intraoperative technique of treating the stump of the main bronchus with a high-energy laser LSP-30 during pneumonectomy, to increase the effectiveness of the treatment of patients with destructive widespread pulmonary ...
G. A. Asoyan, L. N. Lepekha, S. S. Sadovnikova, R. V. Tarasov, V. K. Aliev, M. A. Bagirov   +5 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

MACROPHAGE AND CYTOKINE PROFILES OF BRONCHOALVEOLAR LAVAGE IN NEW AND RELAPSING RESPIRATORY SARCOIDOSIS

Туберкулез и болезни лёгких, 2016
Goal of the study: to investigate structural and functional specific features of macrophages and cytokine profiles of bronchoalveolar lavage in new and relapsing respiratory sarcoidosis (RS).Materials and methods.
N. G. Demyanenko, L. N. Lepekha, E. I. Shmelev, M. M. Averbakh, T. A. Statsuk, I. V. Sivokozov   +5 more
doaj   +1 more source

Successful surgical treatment of mediastinal lung hernia with a mesh implant. Consequent results

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
An observation from practice is given – surgical treatment of mediastinal pulmonary hernia in a patient after pneumonectomy using the method of anterior mediastinal plastic surgery with a mesh implant with demonstration of long-term results.The patient I.
R. V. Tarasov, E. V. Krasnikova, S. S. Sadovnikova, E. A. Shergina, Y. O. Chesalina, M. A. Bagirov   +5 more
doaj   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

ANALYSIS OF SURGERIES DUE TO PULMONARY TUBERCULOSIS IN SIBERIAN AND FAR EASTERN FEDERAL DISTRICTS

Туберкулез и болезни лёгких, 2017
The pool of TB infection in Siberian and Far Eastern Federal Districts is still full of complicated cases: among those being followed up by TB dispensaries, there are many patients suffering from fibrous cavernous TB as well as any clinical forms of ...
N. G. Grischenko, D. V. Krasnov, T. V. Alekseeva, K. A. Avdienko, D. A. Skvortsov, M. V. Reykhrud   +5 more
doaj   +1 more source