Results 41 to 50 of about 1,229,168 (350)

Addressing the burden and detection gap of latent tuberculosis infection in schoolchildren and adolescents in China: a cross-sectional study

BMC Infectious Diseases
Background The latent tuberculosis infection (LTBI) burden is still unclear in schoolchildren and adolescents in China. Previous study and daily surveillance data indicate a LTBI detection gap.
Bo Wu, Ya Yu, Chengguo Wu, Yaling Shi, Ying Liu, Jin Yin, Qian Su, Zhengyu Zhang, Xueyong Huang, Mei Wang, Yan Pang, Jiyuan Zhong, Jun Fan   +12 more
doaj   +1 more source

Immunology of Mycobacterium tuberculosis Infections

Microbiology spectrum, 2019
Tuberculosis (TB) is a serious global public health challenge that results in significant morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium tuberculosis (M.
J. K. Sia, Jyothi Rengarajan
semanticscholar   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

The role of chest X-ray in tuberculosis detection for high school students in China: a cross-sectional study

Scientific Reports
In China, pulmonary tuberculosis (PTB) screening for children and adolescents is not only focused on family contacts, but also students in high schools. The research objective is to investigate chest X-ray (CXR) abnormalities and its risk factors.
Mei Wang, Jin Yin, Chengguo Wu, Yaling Shi, Ying Liu, Jun Rao, Dan Li, Qian Su, Zhengyu Zhang, Xueyong Huang, Ya Yu, Jun Fan, Bo Wu   +12 more
doaj   +1 more source

Tuberculosis and the Heart [PDF]

, 2021
José López-López, Edith Liliana Posada‐Martínez, Clara Saldarriaga, Fernando Wyss, Carlos I. Ponte‐Negretti, Bryce Alexander, Andrés F. Miranda‐Arboleda, Manuel Martínez‐Sellés, Adrián Baranchuk, the Neglected Tropical Diseases, Other Infectious Diseases Affecting the Heart (the NET‐Heart Project)   +9 more
openalex   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Effectiveness of a smoking cessation support program for tuberculosis patients in Japan

Tobacco Induced Diseases, 2019
In Japan, the current smoker rate in tuberculosis (TB) patients is higher than that of the general population. The data show that more than half of them keep smoking throughout their treatment period.
Tamae Shimamura, Minako Urakawa, Yoko Nagata, Toru Mori   +3 more
doaj   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

PERSONAL FEATURES OF CHILDREN AND ADOLESCENTS ILL WITH RESPIRATORY TUBERCULOSIS EXPOSED AND NOT EXPOSED TO THE SOURCE OF INFECTION

Туберкулез и болезни лёгких, 2017
Specific personal features of 296 children and adolescents exposed to tuberculosis and those with unidentified exposure were comparatively analyzed. Children with unidentified exposure demonstrated psychic tension, poor self-control, poorly developed ...
N. V. Zolotova, A. A. Akhtyamova, V. V. Streltsov, G. V. Baranova, E. S. Ovsyankina, N. V. Yukhimenko   +5 more
doaj   +1 more source

An Interferon-Inducible Neutrophil-Driven Blood Transcriptional Signature in Human Tuberculosis

Nature, 2010
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with diagnosis, prevention and treatment.
M. Berry, C. Graham, Finlay W Mcnab, Zhaohui Xu, S. Bloch, T. Oni, K. Wilkinson, R. Banchereau, Jason A. Skinner, R. Wilkinson, Charlie Quinn, D. Blankenship, R. Dhawan, J. Cush, A. Mejías, O. Ramilo, O. Kon, V. Pascual, J. Banchereau, D. Chaussabel, A. O’Garra   +20 more
semanticscholar   +1 more source