Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang +8 more
wiley +1 more source
Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
Prevalence of Nontuberculous Mycobacteria Infection, China, 2004–2009
Hui Jing +7 more
doaj +1 more source
Organizational and Functional Principles of the Obligate Respiratory Chain Supercomplex
In this review we deliver a comprehensive structural analysis of the actinobacterial respiratory chain supercomplex and discuss the principles underlying the assembly of its supramolecular architecture. ABSTRACT Proton translocating respiratory chain complexes assemble into supramolecular structures in their native cellular environment, yet the ...
Wei‐Chun Kao, Nick Hiatt, Carola Hunte
wiley +1 more source
Potential of Pan-Tuberculosis Treatment to Drive Emergence of Novel Resistance
New tuberculosis (TB) drugs with little existing antimicrobial resistance enable a pan-TB treatment regimen, intended for universal use without prior drug-susceptibility testing.
C. Finn McQuaid +5 more
doaj +1 more source
Molecular detection of Mycobacterium bovis in the environment [PDF]
An investigation was carried out to determine the presence and persistence of Mycobacterium bovis in the environment. Soil samples were taken in April 2000 from a farm in Ireland which had undergone a bovine tuberculosis outbreak some four months ...
Young, Jamie Stuart
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Development of medical point-of-care applications for renal medicine and tuberculosis based on electronic nose technology [PDF]
INTRODUCTION: Current clinical diagnostics are based on biochemical, immunological or microbiological methods. However, these methods are operator dependent, time consuming, expensive and require special skills, and are therefore not suitable for ...
Fend, Reinhard
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Rapid Microscope Based Identification Method for Tuberculosis and Other Mycobacteria : Fluorescence In Situ Hybridization (FISH) - Current State of The Art and Future Research Needs [PDF]
Tuberculosis (TB) is one of the major increasing causes of illness and death worldwide, especially in Asia and Africa. Rapid and accurate diagnosis of mycobacteria is important in the prevention and effective treatment of tuberculosis.
Lee, Natuschka M.,, Borekci, Gulay
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Increased Pediatric Head and Neck Abscesses Following the COVID‐19 Pandemic
This study evaluated the impact of the COVID‐19 pandemic on pediatric head and neck abscesses at two tertiary care centers. Overall head and neck abscess incidence increased more than threefold in the post‐pandemic period compared with the pre‐pandemic period, with increases observed across all major abscess subtypes.
Marco DiBlasi +4 more
wiley +1 more source
Tuberculosis in Malta : thirty-five years of epidemiological trends in the native population [PDF]
Malta, the smallest island state in Europe, with an approximate population of 400,000, has one of the lowest reported incidence rates for tuberculosis (TB) in its native-born population.1 Long- term trends for TB among this population were investigated.
Gauci, Charmaine +4 more
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