Results 111 to 120 of about 47,249 (313)

Control of (multi)drug resistance and tuberculosis incidence over 23 years in the context of a well-supported tuberculosis programme in rural Malawi. [PDF]

, 2013
BACKGROUND: The rise in tuberculosis (TB) incidence following generalized HIV epidemics can overwhelm TB control programmes in resource-limited settings, sometimes accompanied by rising rates of drug resistance.
Mboma, Sebastian M, Lifted Sichali, Mboma Sebastian M., Houben, Rein M.G.J., Mpunga, James, Fine, Paul E.M., French Neil, Sebastian M Mboma, Glynn, Judith R., James Mpunga, Neil French, Houben, RMGJ, Glynn, Judith R, French, Neil, Glynn Judith R., Crampin, Amelia C, Paul E M Fine, Judith R Glynn, Metcalfe, John Z., Sichali Lifted, Drobniewski, FD, Amelia C Crampin, Mpunga James, Fine Paul E. M., Fine, Paul EM, French, NS, Crampin, Amelia C., Rein M G J Houben, Crampin Amelia C., Sichali, Lifted, Houben Rein M. G. J., Houben, Rein MGJ, Drobniewski, Francis, Glynn, JR, Sichali, L, Mboma, Sebastian M., Crampin, AC, Francis Drobniewski, Mboma, SM, Fine, PEM, Mpunga, J, Drobniewski Francis   +41 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Curry, JM, Strom, M, Buxton, RS, Whalan, R, Hunt, DM, Colston, MJ, Smerdon, SJ, Gohil, K, Rickman, L   +8 more
core  

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Spotlight on the Nucleotide: Solid‐State NMR for the Investigation of ATP Hydrolysis in the ATPase SmsC

Chemistry – A European Journal, EarlyView.
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr, Laure Decamps, Julius Schlüter, Koen Linssen, Georg Künze, Kushal Sengupta, Serena DeBeer, Thomas Wiegand   +7 more
wiley   +1 more source

Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70 [PDF]

, 2005
Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacteriall proteins.
Jungersen, Gregers, Anne K. Storset, Kulberg, Siri, Kulberg, S., Preben Boysen, Boysen, Preben, Jayne C. Hope, Siri Kulberg, Ingrid Olsen, Boysen, P., Storset, Anne K., Olsen, Ingrid, Storset, A.K., Hope, J.C., Gregers Jungersen, Hope, Jayne; id_orcid   +15 more
core   +1 more source

Tenosynovitis due to mycobacteria other than tuberculosis: a hazard of water sports and hobbies

Respiratory Medicine, 1995
Tenosynovitis is defined as inflammation of a tendon sheath. In established cases it often presents as painful swelling associated with gradual loss of movement and palpable synovial thickening with nodularity and crepitus in the affected tendons. The cause of such inflammation may include autoimmune phenomena as in rheumatoid arthritis, bacterial ...
Kiely, J.L., O'Riordan, D.M., Sheehan, S., Curtin, J., Hogan, J., Bredin, C.P.   +5 more
openaire   +2 more sources

Relay Approach: A Convergent Synthesis of Key Fragments en route to (+)‐Neosorangicin A

Chemistry – A European Journal, EarlyView.
A selective synthesis of three key fragments of the antibiotically active (+)‐neosorangicin A is reported, providing a foundation for its convergent total synthesis and proof of strategy via a relay approach. ABSTRACT Herein, we report the synthesis of the three key fragments of the macrolide antibiotic (+)‐neosorangicin A, a compound exhibiting potent
Marvin Wenninger, Maxim Munt, Le Chang, Rositsa Stoykova, Roberto Ojcius, Oliver Spieß, Dieter Schinzer   +6 more
wiley   +1 more source

The innate immune response to Mycobacterium tuberculosis is dependent on strain lineage and on host population [PDF]

, 2013
Includes abstract.Includes bibliographical references.The genome structure of Mycobacterium tuberculosis is strongly clonal, in the absence of horizontal gene transfer.
Sarkar, Rajesh
core  

Clinical Images: A thorn injury, a sea‐borne culprit, and a tenosynovitis dilemma

Arthritis &Rheumatology, EarlyView.
Jacopo Ciaffi, Francesco Mori, Paolo Sassu, Marco Gambarotti, Alberto Righi, Eleonora Zamparini, Marco Innocenti, Marina Tadolini, Francesco Ursini   +8 more
wiley   +1 more source