Results 11 to 20 of about 6,413 (205)

Degradative and synthetic studies on tubocurarine and some related compounds [PDF]

, 1965
The history of curare, its production, the botanical sources and biologically-active constituents of the various curares are reviewed. The derivation of the structure of curine and tubocurarine is discussed together with the total synthesis of ...
Murray, John B
core   +7 more sources

Efficacy of a K⁺ Channel Agonist, XEN1101, For Preserving Contractility in Mouse Models of Hypokalemic Periodic Paralysis. [PDF]

Muscle Nerve
Pretreatment with an agonist of Kv7 potassium channels (XEN1101) protects the soleus muscle from a loss of force during a 2 mM K+ challenge, in a mouse model of hypokalemic periodic paralysis. ABSTRACT Introduction/Aims Effective management remains lacking for recurrent episodes of acute weakness in hypokalemic periodic paralysis (HypoPP).
Chanchykov V, Iype S, Quinonez M, Wu F, Cannon S.   +4 more
europepmc   +2 more sources

COMPARISON OF NEUROMUSCULAR BLOCKADE PRODUCED BY DECAMETHONIUM AND TUBOCURARINE ON ANTAGONISTIC MUSCLES.

, 1955
COMPARISON OF NEUROMUSCULAR BLOCKADE PRODUCED BY DECAMETHONIUM AND TUBOCURARINE ON ANTAGONISTIC ...
STANLEY VLADIMIR. SUSINA (7968056)
core   +6 more sources

Neurotoxicity of a Novel Local Anesthetic Agent, Ropivacaine: The Possible Roles of Bursts of Potential and Cytoplasmic Second Messenger

Journal of the Formosan Medical Association, 2007
Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood.
Pei-Lin Lin, Shou-Zen Fan, Feng-Fong Tsai, Ming-Cheng Tsai, Chia-Hsien Lin, Chi-Hsiang Huang   +5 more
doaj   +1 more source

Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain

Frontiers in Neurology, 2017
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin, Rashid Giniatullin, Irina Shelukhina, Irina Shelukhina, Nikita Mikhailov, Polina Abushik, Leniz Nurullin, Leniz Nurullin, Evgeny E. Nikolsky, Evgeny E. Nikolsky   +9 more
doaj   +1 more source

d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity

Frontiers in Cellular Neuroscience, 2017
Aminoglycoside antibiotics are widely used for the treatment of life-threatening bacterial infections, but cause permanent hearing loss in a substantial proportion of treated patients.
Nerissa K. Kirkwood, Molly O'Reilly, Marco Derudas, Emma J. Kenyon, Rosemary Huckvale, Sietse M. van Netten, Simon E. Ward, Guy P. Richardson, Corné J. Kros   +8 more
doaj   +1 more source

Preliminary studies with a neurotoxin obtained from Bungarus caeruleus venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
The neurotoxin purified from the venom of Bungarus caeruleus causes a neuromuscular blockade on acetylcholine-induced muscle twitch response in isolated frog rectus abdominis muscle preparation.
K. K. Mirajkar, S. More, J. R. Gadag
doaj   +1 more source

Effect of Tubocurarine on the Adrenal Medulla [PDF]

, 1960
In experiments of suprareno-jugular anastomosis on dogs, MALME"JAc and GROSS" provided evidence that tubocurarine was capable of preventing the accelerating action of anoxia on the adrenaline secretion.
Yamashita, Kazukuni, Araki, Mikio, Mitamura, Takaaki   +2 more
core   +2 more sources

Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. [PDF]

PLoS ONE, 2014
Three recently discovered tentacle muscles are crucial to perform patterned movements of upper tentacles of the terrestrial snail, Helix pomatia. The muscles receive central and peripheral excitatory cholinergic innervation lacking inhibitory innervation.
Tibor Kiss, Nóra Krajcs, Zsolt Pirger, László Hernádi   +3 more
doaj   +1 more source

Efeito de alguns curares naturais e da d-Tubocurarina retardando o tempo de coagulação e o tempo de protombina do sangue humano Natural curares and d-Tubocuratine effects on human blood clothing time and prothrombine time

Memorias do Instituto Oswaldo Cruz, 1967
In this paper the author points out to a old question of about 200 years ago in wich two kinds of opinions were discussed. BANCROFT and FONTANA in one hand atributes for the Indian arrow poison (curare) the propriety of uncoagulate the blood, and C ...
João Canali, João Vieira Vieira
doaj   +1 more source