Results 21 to 30 of about 6,413 (205)
L- and DL-carnitine induce tetanic fade in rat neuromuscular preparation
Brazilian Journal of Medical and Biological Research, 2003 Carnitine, a structurally choline-like metabolite, has been used to increase athletic performance, although its effects on neuromuscular transmission have not been investigated. It is present in skeletal muscle and its plasma levels are about 30 to 90 µM.
G. Lopes +3 more
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Acta Scientiarum. Health Sciences, 2008 A acetilcolina liberada do terminal nervoso motor (TNM) pode modular sua própria liberação (automodulação do TNM), interagindo com receptores nicotínicos (autoestimulação do TNM) ou muscarínicos (autoinibição do TNM) pré-juncionais.
Lisliane Marisa Tagliari +1 more
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Toxins, 2020 Gymnodimines and spirolides are cyclic imine phycotoxins and known antagonists of nicotinic acetylcholine receptors (nAChRs). We investigated the effect of gymnodimine A (GYM A) and 13-desmethyl spirolide C (SPX 1) from Alexandrium ostenfeldii on rat ...
Joyce A. Nieva +5 more
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Toxins, 2015 Nicotinic acetylcholine receptors (nAChRs) fulfill a variety of functions making identification and analysis of nAChR subtypes a challenging task. Traditional instruments for nAChR research are d-tubocurarine, snake venom protein α-bungarotoxin (α-Bgt ...
Denis Kudryavtsev +9 more
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Marine Drugs, 2020 The configurational analysis of complex natural products by NMR spectroscopy is still a challenging task. The assignment of the relative configuration is usually carried out by analysis of interproton distances from NOESY or ROESY spectra (qualitative or
Matthias Köck +2 more
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High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor. [PDF]
PLoS ONE, 2016 High throughput random mutagenesis is a powerful tool to identify which residues are important for the function of a protein, and gain insight into its structure-function relation.
Paul J Groot-Kormelink +13 more
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Безопасность и риск фармакотерапии, 2022 The article presents the history of the exploration of arrow poisons, used in Asia, Africa and South America. The active ingredients of these poisonswere widely used and continue to apply currently in traditional and official medicine.
R. N. Alyautdin R.N, B. K. Romanov
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TUBOCURARINE AND RENAL FAILURE
British Journal of Anaesthesia, 1972 SUMMARY Different observations concerning the duration of the neuromuscular blocking effect of tubocurarine in patients with renal failure have been rationalized by pharmacokinetic analysis. Computer simulations predict that absence of renal function will have little effect on the duration of action of relatively small single doses of tubocurarine but
M, Gibaldi, G, Levy, W L, Hayton
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Cardiovascular Effects of Tubocurarine in Man [PDF]
Survey of Anesthesiology, 1978 The cardiovascular effects of tubocurarine in patients anaesthetised with thiopentone or ketamine have been compared, using volume-pulse finger plethysmography, electrocardiography, sphygmomanometry and impedance cardiography for the clinical assessments.
M, Johnstone +2 more
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Brazilian Journal of Medical and Biological Research, 2002 Trimethylsulfonium, a compound present in the midgut gland of the sea hare Aplysia brasiliana, negatively modulates vagal response, indicating a probable ability to inhibit cholinergic responses.
C.M. Kerchove +3 more
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