Results 41 to 50 of about 6,413 (205)
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou +12 more
wiley +1 more source
1. The effect of tubocurarine on amplitudes of end-plate currents in response to trains of repetitive stimulation (50-150/sec) was investigated in voltage-clamped muscle fibres of the rat, mouse and frog. 2.
Terrar, D A +2 more
core +1 more source
Capillary endothelial cell heterogeneity in skeletal muscle of female and male mice
Abstract In skeletal muscle, capillaries have been shown to be critical to active hyperemia by sensing skeletal muscle activity and directing blood flow to contracting muscle fibers. There is evidence to suggest that capillary endothelial cell (EC) characteristics may change along the length of a capillary.
Mackenzie E. Charter, Coral L. Murrant
wiley +1 more source
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
wiley +1 more source
Tubocurarine and Pancuronium: A Pharmacokinetic View [PDF]
This review is an attempt to bring together the pharmacokinetic data on d-tubocurarine and pancuronium with clinical observations on relaxant dosage and effect. The modelling techniques used here represent an oversimplification of the relationships between relaxant plasma concentration and response as they do not predict either the time of onset of ...
C A, Shanks +3 more
openaire +2 more sources
Evaluating Anesthetics for Improving Scientific Research and Welfare Using Larval Zebrafish
Using physiological and behavioral assays, we quantified the effectiveness and appropriateness of six commonly used fish anesthetics on zebrafish embryos. Different anesthetics performed better under different contexts. Figure prepared using BioRender.com.
Sylvia Dimitriadou +15 more
wiley +1 more source
Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine.
BACKGROUND: The diaphragm is resistant to competitive neuromuscular blocking agents. Because of the competitive mechanism of action of tubocurarine, the rate of hydrolysis of acetylcholine at the neuromuscular junction may modulate its neuromuscular ...
Duvaldestin, Philippe +6 more
core +2 more sources
Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro
In this work, we have examined the neuromuscular activity of Micrurus laticollaris (Mexican coral snake) venom (MLV) in vertebrate isolated nerve-muscle preparations.
Alejandro Carbajal-Saucedo +5 more
doaj +1 more source
Curatorial Ways of Making Cities and Navigating Futures Through Urban Experiments
Short Abstract Contemporary curation is profoundly relational, emphasising the importance of the interrelations amongst objects and the enhanced meanings generated through their dialogues with each other and with various publics. In this contribution, we outline a curatorial approach founded in relational geography to inform the co‐construction and ...
Miguel Valdez, Matthew Cook
wiley +1 more source
Effect of Tubocurarine on the Adrenal Medulla [PDF]
In experiments of suprareno-jugular anastomosis on dogs, MALME"JAc and GROSS" provided evidence that tubocurarine was capable of preventing the accelerating action of anoxia on the adrenaline secretion.
Yamashita, Kazukuni +2 more
core +1 more source

