Results 101 to 110 of about 420,141 (304)

Measuring and modeling polymer gradients argues that spindle microtubules regulate their own nucleation

, 2017
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Foster, Peter J., Fürthauer, Sebastian, Kaye, Bryan, Needleman, Daniel J., Shelley, Michael J., Stiehl, Olivia   +5 more
core   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

Advanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou, Jiongyi Yan, Dick F. Firdaus, Amy Jin, Jiaxuan Li, Shushan Wang, Ran Chen, Xudong Tao, Zehao Ji, Yi Liu, Zichen Wang, Christos Margadji, Mark Kotter, J. Axel Zeitler, George G. Malliaras, Ronan Daly, Andrew Gleadall, Sebastian W. Pattinson   +17 more
wiley   +1 more source

3D-QSAR, molecular docking, ADMET, simulation dynamic, and retrosynthesis studies on new styrylquinolines derivatives against breast cancer

Open Chemistry
Breast cancer is the most common illness among women, accounting for 25% of all diagnoses, as stated by the American Cancer Society. Current research focuses on 43 compounds of styrylquinoline derivatives as potential inhibitors of tubulin to design a ...
EL-Mernissi Reda, Alaqarbeh Marwa, Khaldan Ayoub, Kara Mohammed, Al kamaly Omkulthom, Alnakhli Anwar M., Lakhlifi Tahar, Sbai Abdelouahid, Ajana Mohammed Aziz, Bouachrine Mohammed   +9 more
doaj   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Editorial: Cytoskeleton Dynamics as Master Regulator of Organelle Reorganization and Intracellular Signaling for Cell-Cell Competition

Frontiers in Cell and Developmental Biology, 2021
Noa B. Martin-Cofreces, Noa B. Martin-Cofreces, Noa B. Martin-Cofreces, Francisco Sanchez-Madrid, Francisco Sanchez-Madrid, Francisco Sanchez-Madrid, Pedro Roda-Navarro, Pedro Roda-Navarro   +7 more
doaj   +1 more source

Model of ionic currents through microtubule nanopores and the lumen

, 2009
It has been suggested that microtubules and other cytoskeletal filaments may act as electrical transmission lines. An electrical circuit model of the microtubule is constructed incorporating features of its cylindrical structure with nanopores in its ...
A. M. Gomez, Avner Priel, D. K. Meyer, Eric Carpenter, Holly Freedman, J. A. Tuszynski, J. A. Tuszynski, Jack A. Tuszynski, Sergei Y. Noskov, V. A. Maltsev, Vahid Rezania   +10 more
core   +1 more source

Additional file 1 of The oncogenic role of tubulin alpha-1c chain in human tumours

, 2022
Xinyao Hu, Hua Zhu, Biao Chen, Xiaoqin He, Yang Shen, Xiaoyu Zhang, Yangtao Xu, Ximing Xu   +7 more
openalex   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source