Results 21 to 30 of about 619,494 (287)

Influencing Factors and Significance of Tumor-associated Macrophage Polarization 
in Tumor Microenvironment

Chinese Journal of Lung Cancer, 2023
Tumor-associated macrophages (TAMs), characterized by high plasticity, are the most abundant immune cells in the tumor microenvironment (TME). TAMs are recruited to tumor region in response to various TME components such as cytokines, chemokines as well ...
Wenke GE, Weibing WU
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Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages [PDF]

, 2007
Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)‐induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy.
Barleon, Cho, de Felipe, Dong, Donnelly, Dvorak, Elaine Y. Lin, Eubank, Ferrara, Ferrara, Folkman, Gabriel Bricard, Giraudo, Gouon-Evans, Grunewald, Gunther, Guy, Hanahan, Jain, Jeffrey W. Pollard, Jiu-feng Li, Keyt, Kumaraswamy, Leek, Leek, Leek, Leung, Lewis, Lin, Lin, Lin, Lin, Lobov, Mok, Naumov, Pollard, Rani Sellers, Ross, Sasmono, Schoeffner, Scholl, Shima, Steven A. Porcelli, Sunderkotter, Varney, Weigang Wang, Yan Deng, Yoshida   +47 more
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Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]

, 2018
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D, Chavez, Michael, Davis, Ryan R, Ferrara, Katherine W, Fite, Brett Z, Hubbard, Neil E, Ilovitsh, Asaf, Ingham, Elizabeth S, Mahakian, Lisa M, Monjazeb, Arta M, Murphy, William J, Silvestrini, Matthew T, Tam, Sarah M, Tepper, Clifford G   +13 more
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CD169+ Macrophages Residing in the Draining Lymph Nodes and Infiltrating the Tumor Play Opposite Roles in the Pathogenesis of Bladder Cancer

Research and Reports in Urology, 2023
Masakazu Nagata,1 Kazuhiro Ishizaka,1 Touko Asano1,2 1Department of Urology, Teikyo University Hospital Mizonokuchi, Kawasaki, Kanagawa, Japan; 2Department of Urology, Omori Red Cross Hospital, Ota, Tokyo, JapanCorrespondence: Touko Asano, Department of ...
Nagata M, Ishizaka K, Asano T
doaj  

Immune Microenvironment in Glioblastoma Subtypes

Frontiers in Immunology, 2018
Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers.
Zhihong Chen, Dolores Hambardzumyan
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Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]

, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália, Bonfanti, Amanda Pires, Brunetto, Sérgio, Caballero, Marcus, Cordeiro, Gabriel, Moura, Fernanda, Munhoz, Jaqueline, Ramos, Celso Dario, Rapôso, Catarina, Rocha-E-Silva, Thomaz, Sutti, Rafael, Thome, Rodolfo, Verinaud, Liana   +12 more
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The role of tumor-associated macrophages in tumor vascularization [PDF]

, 2013
Tumor vascularization is a highly complex process that involves the interaction between tumors and their surrounding stroma, as well as many distinct angiogenesis-regulating factors.
Buranych, Annicole, Fisher, Paul B., Guo, Chunqing, Sarkar, Devanand, Wang, Xiang-Yang   +4 more
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The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid. [PDF]

, 2014
We previously defined macrophages harvested from the peritoneal cavity of nude mice with subcutaneous human pancreatic tumors as "tumor-educated-macrophages" (Edu) and macrophages harvested from mice without tumors as "naïve-macrophages" (Naïve), and ...
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hassanein, Mohamed K, Hiroshima, Yukihiko, Hoffman, Robert M, Ichikawa, Yasushi, Maawy, Ali, Matsuyama, Ryusei, Menen, Rhiana, Miwa, Shinji, Momiyama, Masashi, Mori, Ryutaro, Murakami, Takashi, Tanaka, Kuniya, Uehara, Fuminari, Yamamoto, Mako, Yano, Shuya   +17 more
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Advances in the Study of Tumor-associated Macrophages in Lung Cancer

Chinese Journal of Lung Cancer, 2022
Lung cancer is one of the malignant tumors with the highest morbidity and mortality in China. Therefore, the research on the treatment of lung cancer is also deepening.
Yanyan QIAO, Enqing FU
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Research Progress of M2-type Tumor-associated Macrophages in Lung Cancer

Zhongliu Fangzhi Yanjiu, 2022
Tumor-associated macrophages (TAMs) account for a large proportion in tumor stroma, and can be divided into M1 type (anti-tumoral) and M2 type (pro-tumoral).
WAN Xiaoying, ZHOU Songwen
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