Results 11 to 20 of about 414,820 (218)
Notch Signaling in Macrophages in the Context of Cancer Immunity
Frontiers in Immunology, 2018 Macrophages play both tumor-suppressing and tumor-promoting roles depending on the microenvironment. Tumor-associated macrophages (TAMs) are often associated with poor prognosis in most, but not all cancer.
Tanapat Palaga +5 more
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Biomedicines, 2023 Background: Hepatocellular carcinoma is the sixth most diagnosed malignancy and the fourth most common cause of cancer-related mortality globally. Despite progress in the treatment of liver cancer, nonsurgical treatments remain unsatisfactory, and only ...
Hsin-Lun Lee +6 more
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Chinese Journal of Lung Cancer, 2023 Tumor-associated macrophages (TAMs), characterized by high plasticity, are the most abundant immune cells in the tumor microenvironment (TME). TAMs are recruited to tumor region in response to various TME components such as cytokines, chemokines as well ...
Wenke GE, Weibing WU
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Research and Reports in Urology, 2023 Masakazu Nagata,1 Kazuhiro Ishizaka,1 Touko Asano1,2 1Department of Urology, Teikyo University Hospital Mizonokuchi, Kawasaki, Kanagawa, Japan; 2Department of Urology, Omori Red Cross Hospital, Ota, Tokyo, JapanCorrespondence: Touko Asano, Department of ...
Nagata M, Ishizaka K, Asano T
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Immune Microenvironment in Glioblastoma Subtypes
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers.
Zhihong Chen, Dolores Hambardzumyan
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Advances in the Study of Tumor-associated Macrophages in Lung Cancer
Chinese Journal of Lung Cancer, 2022 Lung cancer is one of the malignant tumors with the highest morbidity and mortality in China. Therefore, the research on the treatment of lung cancer is also deepening.
Yanyan QIAO, Enqing FU
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Research Progress of M2-type Tumor-associated Macrophages in Lung Cancer
Zhongliu Fangzhi Yanjiu, 2022 Tumor-associated macrophages (TAMs) account for a large proportion in tumor stroma, and can be divided into M1 type (anti-tumoral) and M2 type (pro-tumoral).
WAN Xiaoying, ZHOU Songwen
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Progress of research on the relationship between efferocytosis and tumor
Frontiers in OncologyTumors are genetic changes that develop in an organism as a result of many internal and external causes. They affect the biological behavior of cells, cause them to grow independently, and give rise to new, perpetually proliferating organisms.
Xuexin Yao +4 more
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Ontogeny of Tumor-Associated Macrophages
Frontiers in Immunology, 2019 Tumor-associated macrophages (TAM) represent the main immune cell population of the tumor microenvironment in most cancer. For decades, TAM have been the focus of intense investigation to understand how they modulate the tumor microenvironment and their ...
Marie Laviron, Alexandre Boissonnas
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Clinical and Translational Medicine, 2021 Neuroblastoma (NB) is the most common and deadliest pediatric solid tumor. Targeting and reactivating tumor‐associated macrophages (TAMs) is necessary for reversing immune suppressive state and stimulating immune defense to exert tumoricidal function ...
Lei Miao +7 more
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