Results 21 to 30 of about 9,505,976 (163)
Biomedicines, 2023 Background: Hepatocellular carcinoma is the sixth most diagnosed malignancy and the fourth most common cause of cancer-related mortality globally. Despite progress in the treatment of liver cancer, nonsurgical treatments remain unsatisfactory, and only ...
Hsin-Lun Lee +6 more
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Research and Reports in Urology, 2023 Masakazu Nagata,1 Kazuhiro Ishizaka,1 Touko Asano1,2 1Department of Urology, Teikyo University Hospital Mizonokuchi, Kawasaki, Kanagawa, Japan; 2Department of Urology, Omori Red Cross Hospital, Ota, Tokyo, JapanCorrespondence: Touko Asano, Department of ...
Nagata M, Ishizaka K, Asano T
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Immune Microenvironment in Glioblastoma Subtypes
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers.
Zhihong Chen, Dolores Hambardzumyan
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Advances in the Study of Tumor-associated Macrophages in Lung Cancer
Chinese Journal of Lung Cancer, 2022 Lung cancer is one of the malignant tumors with the highest morbidity and mortality in China. Therefore, the research on the treatment of lung cancer is also deepening.
Yanyan QIAO, Enqing FU
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Engineering the tumor microenvironment of colorectal cancer [PDF]
, 2014 The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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, 2023 High-dose acetaminophen (AAP) with N-acetylcysteine (NAC) rescue is among the few treatments that has shown activity in phase I trials without achieving dose-limiting toxicity that has not progressed to evaluation in later line studies.
Won Sok Lee +9 more
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Cathepsin inhibition modulates metabolism and polarization of tumor-associated macrophages
, 2020 Stroma-infiltrating immune cells, such as tumor-associated macrophages (TAM), play an important role in regulating tumor progression and chemoresistance. These effects are mostly conveyed by secreted mediators, among them several cathepsin proteases.
Michl, Patrick +15 more
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, 2023 Tumor-associated macrophages (TAMs) play a pivotal role in shaping the tumor microenvironment. Lactic acid (LA) has been identified as an influential factor in promoting immune escape and tumor progression.
Zhaozhong Zhong +6 more
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, 2021 Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant disease with a 5-year survival rate of less than 10%. Macrophages are one of the earliest infiltrating cells in the pancreatic tumor microenvironment, and are associated with an increased
Ashleigh R. Poh, Matthias Ernst
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Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome. [PDF]
, 2016 Tumor-associated macrophages (TAM) play a controversial role in epithelial-mesenchymal transition (EMT) and prognosis of colorectal cancer (CRC). In particular, the microlocalization, polarization and prognostic impact of TAM in the immediate environment
Canonica, Katharina +8 more
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