Ketogenic diet as a systems-level immunometabolic sensitization strategy in cancer therapy: integrating metabolism, immune reprogramming, microbiome dynamics, and epigenetic regulation. [PDF]
Mannan MS +5 more
europepmc +1 more source
Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
wiley +1 more source
Endotoxins and Biological Implications—Review
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq +5 more
wiley +1 more source
A risk prediction model for metachronous peritoneal metastasis after radical gastrectomy in gastric cancer based on peripheral blood inflammatory markers and tumor pathological features. [PDF]
Dong L, Zhang R, Xu C, Chen L.
europepmc +1 more source
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
wiley +1 more source
Editorial: New Insights on Sialic Acid and Sialylated Glycans in the Tumorigenic Process. [PDF]
Willand-Charnley RA.
europepmc +1 more source
Long‐term survival after surgical removal of an intermediate grade pancreatic carcinoma in a cat
Abstract An 11‐year‐old male neutered domestic shorthair cat presented with a history of acute diarrhoea, decreased appetite, and a palpable abdominal mass. Following clinical staging and histopathological examination after partial pancreatectomy, the cat was diagnosed with a completely excised intermediate grade pancreatic carcinoma without evidence ...
Abel Verbrugghe +4 more
wiley +1 more source
Immunomodulation by glycosylation: bridging glycobiology to adaptive immunity and therapeutic innovation. [PDF]
Ding S, Wang H, Han Z, Hong S.
europepmc +1 more source
ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang +4 more
wiley +1 more source

