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Current opinions on CEA in the diagnosis and prognosis of colorectal cancer. [PDF]
Transl OncolHan Q, Zhu Y, Xing F, Xia Y.
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Journal of Gastroenterology and Hepatology, Volume 41, Issue 7, Page 1991-1993, July 2026.
Soon Kyu Lee +2 more
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Elevation of tumor-associated carbohydrate antigens in patients with diffuse panbronchiolitis
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Possible functions of tumor-associated carbohydrate antigens
Current Opinion in Immunology, 1991Expression of some tumor-associated carbohydrate antigens may define the stage, rate and phenotype of tumor progression and may have prognostic value. Some of these antigens are now recognized as adhesion molecules that define the site of metastasis. Monoclonal antibodies to tumor-associated carbohydrate antigens, or the antigens themselves, may serve ...
S Hakomori
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Advances in Carbohydrate Chemistry and Biochemistry, 2017
Carcinomas express unique carbohydrates, known as tumor-associated carbohydrate antigens (TACAs), on their surface. These are potential targets for anticancer vaccines; however, to date, no such vaccine has reached the clinic. One factor that may complicate the success of this effort is the lability of the glycosidic bond. Acetal-free carbohydrates are
Michael R Reynolds, John F Trant
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Carcinomas express unique carbohydrates, known as tumor-associated carbohydrate antigens (TACAs), on their surface. These are potential targets for anticancer vaccines; however, to date, no such vaccine has reached the clinic. One factor that may complicate the success of this effort is the lability of the glycosidic bond. Acetal-free carbohydrates are
Michael R Reynolds, John F Trant
exaly +3 more sources
Recent Advance in Tumor-associated Carbohydrate Antigens (TACAs)-based Antitumor Vaccines
ACS Chemical Biology, 2016Cancer cells can be distinguished from normal cells by displaying aberrant levels and types of carbohydrate structures on their surfaces. These carbohydrate structures are known as tumor-associated carbohydrate antigens (TACAs). TACAs were considered as promising targets for the design of anticancer vaccines. Unfortunately, carbohydrates alone can only
Abdul Sami Shaikh, Fengshan Wang
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Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate–carbohydrate interactions [PDF]
Glycobiology, 2018 The mucin-type O-glycome in cancer aberrantly expresses the truncated glycans Tn (GalNAcα1-Ser/Thr) and STn (Neu5Acα2,6GalNAcα1-Ser/Thr). However, the role of Tn and STn in cancer and other diseases is not well understood.
Marit Sletmoen +2 more
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Tumor‐associated carbohydrate antigens: A possible avenue for cancer prevention
Immunology & Cell Biology, 2005Here we examine the use of glycopeptides containing tumour‐associated carbohydrate antigens (TACA) as potential preventive vaccines for carcinomas. Our recent results suggest that CD8+ T cells (CTL) are capable of recognizing TACA in a conventional class I MHC‐restricted fashion.
Yanfei, Xu +4 more
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