Results 251 to 260 of about 612,424 (282)

GPR34 inhibition reprograms tumor-associated macrophages and enhances the sensitivity of anti-PD-1 therapy in hepatocellular carcinoma. [PDF]

Cancer Cell Int
Liu W, Yu Q, Liu X, Zhang F, Jiang Q, Tang W, Dong L.   +6 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Tumor associated macrophages and ‘NO’

Biochemical Pharmacology, 2020
Nitric oxide (NO) and its pro and anti-tumor activities are dual roles that continue to be debated in cancer biology. The cell situations in the tumor and within the tumor microenvironment also have roles involving NO. In early tumorigenic events, macrophages in the tumor microenvironment promote tumor cell death, and later are reprogramed to support ...
Niharika Nath, Khosrow Kashfi
openaire   +2 more sources

Metabolism in tumor-associated macrophages

2022
Macrophages functionally adapt to a diverse set of signals, a process that is critical for their role in maintaining or restoring tissue homeostasis. This process extends to cancer, where macrophages respond to a series of inflammatory and metabolic cues that direct a maladaptive healing response.
Jie, Li, Gina M, DeNicola, Brian, Ruffell   +2 more
openaire   +2 more sources

Phenotyping Tumor-Associated Macrophages

2018
Multi-parametric flow cytometry of tumor-bearing murine nonlymphoid tissue allows for characterization, isolation, and examination of immune cell composition, phenotype, and function. Here we describe an approach to process nonlymphoid tissues and then utilize a base antibody panel to define all of the major immune cell types in a single staining ...
R, Ian Cumming, Yen-Rei A, Yu
openaire   +2 more sources

Tumor-associated macrophages in cancers

Clinical and Translational Oncology, 2015
Tumor-associated macrophages (TAMs) are major component of leukocytic infiltrate of tumors and play important roles in progression and regression of tumors. Tumor microenvironment determines the mutual conversion between M1 and M2 macrophages. In many kinds of tumors, M2 type macrophages are of the majority in TAMs and promote tumor progression and ...
W, Hu, X, Li, C, Zhang, Y, Yang, J, Jiang, C, Wu   +5 more
openaire   +2 more sources

Lipid Metabolism in Tumor-Associated Macrophages

2021
Macrophages are essential components of the immune system in tumors. It can be recruited and educated to two mainly polarized subpopulations (M1-like and M2-like) of tumor-associated macrophages (TAMs) to display anti-tumor or protumor function during the tumor occurrence and progression.
Yuancai, Xiang, Hongming, Miao
openaire   +2 more sources

Therapeutic targeting of tumor-associated macrophages

2021
Tumor-associated macrophages are among the most abundant non-cancerous cells in the tumor microenvironment and in many cancers macrophage infiltration into the tumor is associated with poor prognosis. Macrophages contribute to tumor development by promoting angiogenesis and immune suppression, and display remarkable phenotypic heterogeneity in the ...
Rasmussen, Rikke Kongsgaard, Etzerodt, Anders   +1 more
openaire   +3 more sources

Tumor associated macrophages in gynecologic cancers

Gynecologic Oncology, 2018
The complex tumor microenvironment in gynecologic cancers plays a major role in modulating anti-tumor immune responses. The interaction of cancer cells with the diverse spectrum of immune effector cells has an important impact on the efficacy of standard chemotherapy and novel immunotherapy approaches.
Venkatesh Krishnan, Bruce Schaar, Supreeti Tallapragada, Oliver Dorigo   +3 more
openaire   +2 more sources

Tumor-associated macrophages: a short compendium

Cellular and Molecular Life Sciences, 2019
Macrophages play an important role in tissue development and homeostasis. They serve as a nexus between adaptive and innate immunity, and employ considerable plasticity. In cancer, they play a pivotal role in chronic inflammation and tumor growth either by directly stimulating the proliferation of cancer cells or by producing angiogenic and ...
Prenen H., Mazzone M.
openaire   +3 more sources

Immunoregulating activity of tumor-associated macrophages

Cancer Immunology Immunotherapy, 1986
In this report, we examine the antigen nonspecific immunoregulating activity of macrophages isolated from the murine methylcholanthrene-induced fibrosarcoma FSA. These cells were shown to enhance the primary anti-CRBC PFC response of whole normal spleen cells in a dose-dependent fashion.
G J, Dougherty, W H, McBride
openaire   +2 more sources