Results 31 to 40 of about 337,127 (342)

Engineering the tumor microenvironment of colorectal cancer [PDF]

, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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Immunobiology of IL-17A in human colorectal cancer [PDF]

, 2015
During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
core   +1 more source

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers.

Journal of Clinical Oncology, 2019
PURPOSE The aim of the current study was to conduct a pooled analysis of studies that have investigated the prognostic value of tumor-infiltrating lymphocytes (TILs) in early-stage triple negative breast cancer (TNBC). METHODS Participating studies had
S. Loi, D. Drubay, S. Adams, G. Pruneri, P. Francis, M. Lacroix-Triki, H. Joensuu, M. Dieci, S. Badve, S. Demaria, R. Gray, E. Munzone, J. Lemonnier, C. Sotiriou, M. Piccart, P. Kellokumpu-Lehtinen, A. Vingiani, K. Gray, F. André, C. Denkert, R. Salgado, S. Michiels   +21 more
semanticscholar   +1 more source

Vaccinia virus expressing ICP47 : a novel platform for cancer vaccines highlighting tumor epitopes and hiding viral antigens [PDF]

, 2010
Background Recombinant poxviruses expressing tumor associated antigens (TAAs) are evaluated since 20 years as immunogenic vaccine vector in clinical trials.
Raafat, Nermin Abdel Fattah
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Expression of PD-1 on CD4+ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer

Journal of Immunology Research, 2018
Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao, Jian Zhang, Feng Shi, Zhi-Ping Hu, Jiang-Ping Wu, Guang-Jiang Wu, Rui-Bin Wang, Quan Zhou, Hong Chang, Ying-Nan Li, Qing-Kun Song   +10 more
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PD-L1 expression on stromal tumor-infiltrating lymphocytes is a favorable prognostic factor in ovarian serous carcinoma

Journal of Ovarian Research, 2019
Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim, Kyung Un Choi, Ahrong Kim, So Jung Lee, Jung Hee Lee, Dong Soo Suh, Byung-su Kwon, Chungsu Hwang   +7 more
doaj   +1 more source

The expression of programmed death 1 in tumor-infiltrating lymphocytes of hepatocellular carcinoma and its correlation with prognosis

Zhongguo aizheng zazhi, 2021
Background and purpose: Programmed death 1 (PD-1) plays an important role in the regulation of peripheral immune tolerance. The expression of PD-1 in tumor-infiltrating lymphocytes of hepatocellular carcinoma (HCC) and the relationship between PD-1 ...
肖　锋, 肖静文, 邵建国, 陈丽燕, 顾春燕   +4 more
doaj  

The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis

Scientific Reports, 2020
Tumor-infiltrating lymphocytes (TILs) are an important histopathologic feature of colorectal cancer that confer prognostic information. Previous clinical and epidemiologic studies have found that the presence and quantification of tumor-infiltrating ...
Gregory E. Idos, Janet Kwok, Nirupama Bonthala, Lynn Kysh, S. Gruber, C. Qu   +5 more
semanticscholar   +1 more source

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos, Felipe Correa da Silva, Julia Pedron, Roque Domingos Furian, Cristina Fortes, Renan Rangel Bonamigo   +5 more
doaj   +1 more source

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

npj Breast Cancer, 2020
Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive biomarkers in triple-negative (TNBC) and HER2-positive breast cancer. Incorporating sTILs into clinical practice necessitates reproducible assessment.
Z. Kos, Elvire Roblin, Rim S. Kim, S. Michiels, B. Gallas, Weijie Chen, K. K. van de Vijver, S. Goel, S. Adams, S. Demaria, G. Viale, T. Nielsen, S. Badve, W. Symmans, C. Sotiriou, D. Rimm, S. Hewitt, C. Denkert, S. Loibl, S. Luen, J. Bartlett, P. Savas, G. Pruneri, D. Dillon, M. Cheang, A. Tutt, Jacqueline A. Hall, M. Kok, H. Horlings, A. Madabhushi, J. A. van der Laak, F. Ciompi, A. Laenkholm, E. Bellolio, T. Gruosso, S. Fox, J. Araya, G. Floris, J. Hudeček, L. Voorwerk, Andrew H. Beck, J. Kerner, D. Larsimont, S. Declercq, G. G. Van den Eynden, L. Pusztai, A. Ehinger, Wentao Yang, K. AbdulJabbar, Yinyin Yuan, Rajendra Singh, C. Hiley, Maise Al Bakir, A. Lazar, S. Naber, S. Wienert, Miluska Castillo, G. Curigliano, M. Dieci, F. André, C. Swanton, J. Reis-Filho, J. Sparano, E. Balslev, I. Chen, E. Stovgaard, K. Pogue-Geile, K. Blenman, F. Penault-Llorca, S. Schnitt, S. Lakhani, A. Vincent‐Salomon, F. Rojo, J. Braybrooke, M. Hanna, M. T. Soler-Monsó, D. Bethmann, C. Castañeda, K. Willard-Gallo, Ashish Sharma, H. Lien, S. Fineberg, J. Thagaard, L. Comerma, P. Gonzalez-Ericsson, E. Brogi, S. Loi, J. Saltz, Frederick Klaushen, L. Cooper, M. Amgad, D. Moore, R. Salgado, A. A. I. A. A. A. A. A. A. M. A. Hyytiäinen Hida Thompson Lefevre Gown Lo Sapino Mo, Aini Hyytiäinen, A. Hida, A. Thompson, A. Lefevre, A. Gown, Amy A. Lo, A. Sapino, Andre Moreira, A. Richardson, A. Vingiani, A. Bellizzi, Á. Guerrero, A. Grigoriadis, A. Garrido-Castro, A. Cimino-Mathews, A. Srinivasan, B. Acs, Baljit Singh, B. Calhoun, Benjamin Haibe-Kans, B. Solomon, B. Thapa, B. Nelson, Carmen Ballesteroes-Merino, C. Criscitiello, Carolien Boeckx, C. Colpaert, C. Quinn, C. Chennubhotla, C. Solinas, D. Drubay, Dhanusha Sabanathan, D. Peeters, D. Zardavas, D. Höflmayer, Douglas B. Johnson, E. Thompson, E. Perez, E. Elgabry, E. Blackley, Emily S. Reisenbichler, E. Chmielik, F. Gaire, F. Lu, Farid Azmoudeh-Ardalan, F. Peale, F. Hirsch, Gabriela Acosta-Haab, G. Farshid, G. Broeckx, H. Koeppen, H. Haynes, H. McArthur, H. Joensuu, Helena Olofsson, I. Cree, I. Nederlof, I. Frahm, I. Brčić, Jack Junjie Chan, James Ziai, J. Brock, Jelle Weseling, J. Giltnane, J. Lemonnier, J. Zha, J. Ribeiro, J. Lennerz, J. Carter, J. Hartman, J. Hainfellner, J. Le Quesne, J. Juco, J. G. van den Berg, Joselyn Sanchez, J. Cucherousset, J. Adam, J. Balko, K. Saeger, K. Siziopikou, K. Sikorska, K. Weber, K. Steele, K. Emancipator, K. El Bairi, K. Allison, Konstanty Korski, L. Buisseret, Leming Shi, L. Kooreman, L. Molinero, M. V. Estrada, M. van Seijen, M. Lacroix-Triki, Manu Sebastian, M. Balancin, M. Mathieu, M. J. van de Vijver, M. Rebelatto, M. Piccart, M. Goetz, M. Preusser, M. Khojasteh, M. Sanders, M. Regan, Michael Barnes, M. Christie, M. Misialek, M. Ignatiadis, Michiel de Maaker, M. V. van Bockstal, N. Harbeck, N. Tung, Nele Laudus, N. Sirtaine, N. Burchardi, N. Ternès, N. Radosevic-Robin, O. Gluz, O. Grimm, P. Nuciforo, P. Jank, Pawan Kirtani, P. Watson, Peter Jelinic, P. Francis, P. Russell, R. Pierce, R. Hills, R. Leon-Ferre, R. De Wind, R. Shui, S. Leung, S. Tabbarah, Sandra C. Souza, S. O'toole, S. Swain, S. Dudgeon, S. Willis, Scott Ely, S. Bedri, Sheeba Irshad, Shiwei Liu, S. Hendry, S. Bianchi, S. Bragança, S. Paik, Sua Luz, T. Gevaert, Timothy d’Alfons, T. John, Tomohagu Sugie, U. Kurkure, V. Bossuyt, Venkata Manem, Vincente Peg Cámaea, W. Tong, W. Tran, Yihong Wang, Y. Allory, Z. Husain, Z. Bagó-Horváth   +255 more
semanticscholar   +1 more source