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Tumor-infiltrating lymphocytes for adoptive cell therapy
, 2022 Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating ...Liu, Hao, McLaughlin, Mark, Sarnaik, Amod A., Pilon-Thomas, Shari +3 morecore +1 more sourceHigher Numbers of T-Bet+ Tumor-Infiltrating Lymphocytes Associate with Better Survival in Human Epithelial Ovarian Cancer
Cellular Physiology and Biochemistry, 2017 Background/Aims: T-bet, a member of the T-box family of transcription factors, is a key marker of type I immune response within the tumor microenvironment, and has been previously reported by us to serve as an important prognostic indicator for human ...Yun Xu, Lujun Chen, Bin Xu, Yuqi Xiong, Min Yang, Xiaohui Rui, Liangrong Shi, Changping Wu, Jingting Jiang, Binfeng Lu +9 moredoaj +1 more sourceMarsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer
Frontiers in Immunology, 2023 IntroductionTumor-infiltrating T lymphocytes in the tumor microenvironment are critical factors influencing the prognosis and chemotherapy outcomes. As a Chinese herbal medicine, Marsdenia tenacissima extract (MTE) has been widely used to treat cancer in Ben Yi, Ben Yi, Shuai Zhang, Suying Yan, Suying Yan, Yanfei Liu, Yanfei Liu, Zhiqiang Feng, Zhiqiang Feng, Tianhao Chu, Tianhao Chu, Jun Liu, Wei Wang, Jun Xue, Chunze Zhang, Yijia Wang +15 moredoaj +1 more sourceReport on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group
npj Breast Cancer, 2020 Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer, as well as many other solid tumors.M. Amgad, E. Stovgaard, E. Balslev, J. Thagaard, Weijie Chen, S. Dudgeon, Ashish Sharma, J. Kerner, C. Denkert, Yinyin Yuan, K. AbdulJabbar, S. Wienert, P. Savas, L. Voorwerk, Andrew H. Beck, A. Madabhushi, J. Hartman, Manu Sebastian, H. Horlings, J. Hudeček, F. Ciompi, D. Moore, Rajendra Singh, Elvire Roblin, M. Balancin, M. Mathieu, J. Lennerz, Pawan Kirtani, I. Chen, J. Braybrooke, G. Pruneri, S. Demaria, S. Adams, S. Schnitt, S. Lakhani, F. Rojo, L. Comerma, S. Badve, M. Khojasteh, W. Symmans, C. Sotiriou, P. Gonzalez-Ericsson, K. Pogue-Geile, Rim S. Kim, D. Rimm, G. Viale, S. Hewitt, J. Bartlett, F. Penault-Llorca, S. Goel, H. Lien, S. Loibl, Z. Kos, S. Loi, M. Hanna, S. Michiels, M. Kok, T. Nielsen, A. Lazar, Z. Bagó-Horváth, L. Kooreman, J. A. van der Laak, J. Saltz, B. Gallas, U. Kurkure, Michael Barnes, R. Salgado, L. Cooper, A. A. I. A. A. A. A. A. A. M. A. Hyytiäinen Hida Thompson Lefevre Gown Lo Sapino Mo, Aini Hyytiäinen, A. Hida, A. Thompson, A. Lefevre, A. Gown, Amy A. Lo, A. Sapino, Andre Moreira, A. Richardson, A. Vingiani, A. Bellizzi, A. Tutt, A. Guerrero-Zotano, A. Grigoriadis, A. Ehinger, A. Garrido-Castro, A. Vincent‐Salomon, A. Laenkholm, A. Cimino-Mathews, A. Srinivasan, B. Acs, Baljit Singh, B. Calhoun, Benjamin Haibe-Kans, B. Solomon, B. Thapa, B. Nelson, C. Castañeda, Carmen Ballesteroes-Merino, C. Criscitiello, Carolien Boeckx, C. Colpaert, C. Quinn, C. Chennubhotla, C. Swanton, C. Solinas, C. Hiley, D. Drubay, D. Bethmann, D. Dillon, D. Larsimont, Dhanusha Sabanathan, D. Peeters, D. Zardavas, D. Höflmayer, Douglas B. Johnson, E. Thompson, E. Brogi, E. Perez, E. Elgabry, E. Blackley, Emily S. Reisenbichler, E. Bellolio, E. Chmielik, F. Gaire, F. André, F. Lu, Farid Azmoudeh-Ardalan, Forbius Tina Gruosso, F. Peale, F. Hirsch, Frederick Klaushen, Gabriela Acosta-Haab, G. Farshid, G. G. Van den Eynden, G. Curigliano, G. Floris, G. Broeckx, H. Koeppen, H. Haynes, H. McArthur, H. Joensuu, Helena Olofsson, I. Cree, I. Nederlof, I. Frahm, I. Brčić, Jack Junjie Chan, Jacqueline A. Hall, James Ziai, J. Brock, J. Wesseling, J. Giltnane, J. Lemonnier, J. Zha, Joana M. Ribeiro, J. Carter, J. Hainfellner, J. L. Quesne, J. Juco, J. Reis-Filho, J. G. van den Berg, Joselyn Sanchez, J. Sparano, J. Cucherousset, J. Araya, J. Adam, J. Balko, K. Saeger, K. Siziopikou, K. Willard-Gallo, K. Sikorska, K. Weber, K. Steele, K. Emancipator, K. El Bairi, K. Blenman, K. Allison, K. K. van de Vijver, Konstanty Korski, L. Pusztai, L. Buisseret, Leming Shi, L. Shi-wei, L. Molinero, M. V. Estrada, M. van Seijen, M. Lacroix-Triki, M. Cheang, Maise Al Bakir, M. J. van de Vijver, M. Dieci, M. Rebelatto, M. Piccart, M. Goetz, M. Preusser, M. Sanders, M. Regan, M. Christie, M. Misialek, M. Ignatiadis, Michiel de Maaker, M. V. van Bockstal, Miluska Castillo, N. Harbeck, N. Tung, Nele Laudus, N. Sirtaine, N. Burchardi, N. Ternès, N. Radosevic-Robin, O. Gluz, O. Grimm, P. Nuciforo, P. Jank, P. Jelinic, P. Watson, P. Francis, P. Russell, R. Pierce, R. Hills, R. Leon-Ferre, R. De Wind, R. Shui, S. Declercq, S. Leung, S. Tabbarah, Sandra C. Souza, S. O'toole, S. Swain, S. Willis, Scott Ely, Seong-Rim Kim, S. Bedri, Sheeba Irshad, Shiwei Liu, S. Hendry, S. Bianchi, S. Bragança, S. Paik, S. Fox, S. Luen, S. Naber, Sua Luz, S. Fineberg, T. Soler, T. Gevaert, Timothy d’Alfons, T. John, Tomohagu Sugie, V. Bossuyt, Venkata Manem, Vincente Peg Cámaea, W. Tong, Wentao Yang, W. Tran, Yihong Wang, Y. Allory, Z. Husain +257 moresemanticscholar +1 more sourceCTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast
Frontiers in Immunology, 2020 Objective: Cancer-associated fibroblasts (CAFs) were associated with tumor progression in the tumor microenvironment (TME). However, their immunosuppressive roles in protecting cancer cells from the attack by cytotoxic T lymphocytes (CTLs) are not fully ...Hongyu Zhang, Rong Jiang, Jinhua Zhou, Juan Wang, Yuejuan Xu, He Zhang, Yanzheng Gu, Yanzheng Gu, Yanzheng Gu, Fengqing Fu, Fengqing Fu, Fengqing Fu, Yu Shen, Yu Shen, Yu Shen, Guangbo Zhang, Guangbo Zhang, Guangbo Zhang, Lanlan Feng, Xueguang Zhang, Xueguang Zhang, Xueguang Zhang, Youguo Chen, Fangrong Shen +23 moredoaj +1 more sourceExpression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer
, 2013 Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also Kim, Mia, Lazariotou, Maria, Gasser, Martin, Waaga, Ana Maria da Silva Rosa, Martin Gasser, Grimmig, Tanja, Heemann, Uwe, Blaheta, Roman A., Andreas Rosenwald, Igor Tsaur, Meier, Eva, Rosenwald, Andreas, Christoph-Thomas Germer, Martin Grimm, Waaga-Gasser, Ana Maria, Mia Kim, Uwe Heemann, Eva Meier, Roman Blaheta, Ana Maria Waaga-Gasser, Germer, Christoph-Thomas, Tsaur, Igor, Blaheta, Roman, Tanja Grimmig, Grimm, Martin, Maria Lazariotou +25 morecore +1 more source
