Results 111 to 120 of about 91,694,512 (315)

PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications

, 2020
Polydimethylsiloxane (PDMS) is among the most widely used materials for organ-on-chip systems. Despite itsmultiple beneficial characteristics from an engineering point of view, there is a concern about the effect of PDMSon the cells cultured in such ...
Carter, Sarah-Sophia,, Kadekar, Sandeep,, Atif, Abdul Raouf,, Varghese, Oommen P., Mestres, Gemma,, Carter, Sarah-Sophia, Tenje, Maria,, Engqvist, Håkan, Varghese, Oommen P.,, Tenje, Maria, Kadekar, Sandeep, Engqvist, Håkan,, Atif, Abdul Raouf, Lanekoff, Ingela, Lanekoff, Ingela,, Mestres, Gemma   +15 more
core   +1 more source

Microfluidics-Based Technologies for the Assessment of Castration-Resistant Prostate Cancer

Cells
Castration-resistant prostate cancer remains a significant clinical challenge, wherein patients display no response to existing hormone therapies. The standard of care often includes aggressive treatment options using chemotherapy, radiation therapy and ...
Amel Sassi, Lidan You
doaj   +1 more source

Supplementary Materials and Methods from Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks

, 2023
Dylan Z. Kelley, Emily Flam, Evgeny Izumchenko, Ludmila Danilova, Hildegard A. Wulf, Theresa Guo, Dzov A. Singman, Bahman Afsari, Alyza Skaist, Michael Considine, Jane A. Welch, Elena Stavrovskaya, Justin Bishop, William H. Westra, Zubair Khan, Wayne M. Koch, David Sidransky, Sarah J. Wheelan, Joseph A. Califano, Alexander V. Favorov, Elana J. Fertig, Daria A. Gaykalova   +21 more
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A global wire planning scheme for Network-on-Chip. [PDF]

, 2003
As technology scales down, the interconnect for on-chip global communication becomes the delay bottleneck. In order to provide well-controlled global wire delay and efficient global communication, a packet switched Network-on-Chip (NoC) architecture was ...
J. Liu, Tenhunen, Hannu, H Tenhunen, Liu, Jian, Zheng, Li-Rong, Pamunuwa, Dinesh, Liu, J., Zheng, L-R, Pamunuwa, Dinesh B., L-r Zheng, D. Pamunuwa   +10 more
core   +1 more source

Host-microbe-cancer interactions on-a-chip

Frontiers in Bioengineering and Biotechnology
The tumor microbiota has emerged as a pivotal contributor to a variety of cancers, impacting disease development, progression, and therapeutic resistance.
Mauricio G. C. Sousa, Mauricio G. C. Sousa, Mauricio G. C. Sousa, Danielle S. K. Brasino, Madeline Krieger, Duygu A. Dindar, Rebekka Duhen, Rebekka Duhen, Zhenzhen Zhang, Cristiane Miranda Franca, Cristiane Miranda Franca, Cristiane Miranda Franca, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni   +16 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

From Separation on a Chip to Laboratory on a Chip

, 2008
Lab on a Chip (called ""Microfluidics"") has established itself as an important technology in the area..
林炳承, 秦建华
core  

Liquid Biopsy in Colorectal Cancer-Current Status and Potential Clinical Applications

Micromachines, 2018
Colorectal cancer is one of the most frequent solid malignancies worldwide. The treatment is either surgical or multimodal and depends on the stage of the disease at diagnosis. Accurate disease assessment is thus of great importance for choosing the most
Gregor Norcic
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source