Results 41 to 50 of about 68,638 (278)

Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer [PDF]

, 2016
In patients with colorectal cancer (CRC), local and systemic inflammatory responses have been extensively reported to associate with cancer survival. However, the specific signalling pathways responsible for inflammatory responses are not clear. The PTEN/
Bennett, Lindsay, Edwards, Joanne, Horgan, Paul G., McMillan, Donald C., Park, James, Powell, Arfon G.M.T., Roseweir, Antonia K., Van Wyk, Hester C.   +7 more
core   +3 more sources

Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host [PDF]

, 2017
Purpose: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival.
Clark, Jennifer, Edwards, Joanne, Horgan, Paul G., McMillan, Donald C., Park, James H., Quinn, Jean A., Roxburgh, Campbell, Van Wyk, Hester C.   +7 more
core   +1 more source

Ureteric Bud-derivatives in Wilms Tumor and Nephrogenic Rest [PDF]

In Vivo, 2021
Recent studies suggest that not only the nephrogenic blastema but also the ureteric bud is involved in oncogenesis of Wilms' tumor (WT). However, the occurrence of ureteric bud (UB) derivatives in nephrogenic rest is not yet known. The aim of our study was to find UB derivatives in WT.Keratin 17 (KRT17) is expressed exclusively in UB in foetal kidneys.
Beatrix, Sarkany, Gyula, Kovacs, Daniel, Banyai   +2 more
openaire   +2 more sources

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget

Oncotarget, 2010
Epithelial mesenchymal transition (EMT) is proposed as a critical mechanism for the acquisition of malignant phenotypes by epithelial cells. In colorectal cancer, tumor cells having undergone EMT are histologically represented by the presence of tumor buds defined as single cells or small clusters of de-differentiated tumor cells at the invasive front.
Zlobec, Inti, Lugli, Alessandro
openaire   +3 more sources

a retrospective cohort study [PDF]

, 2015
Background Metastasis of colorectal cancer (CRC) is directly linked to patient survival. We previously identified the novel gene Metastasis Associated in Colon Cancer 1 (MACC1) in CRC and demonstrated its importance as metastasis inducer and prognostic ...
Herrmann, Pia, Karamitopoulou, Eva, Koelzer, Viktor H., Lugli, Alessandro, Stein, Ulrike, Zlobec, Inti   +5 more
core   +1 more source

High tumor budding activity may predict poor prognosis in laryngeal squamous cell carcinomas

Indian Journal of Pathology and Microbiology, 2022
Background: Laryngeal squamous cell carcinoma (SCC) which is the most common carcinoma of the respiratory system after lung carcinomas is graded by the World Health Organization (WHO) into three groups as grades 1, 2, and 3.
Çiğdem öztürk, Hüsniye Esra Paşaoğlu, Funda Emre, Tülin Şentürk Ege, Ümit Seza Tetikkurt   +4 more
doaj   +1 more source

Tumor budding of cervical squamous cell carcinoma: epithelial-mesenchymal transition-like cancer stem cells? [PDF]

PeerJ, 2022
Recent evidence indicates that cancer stem cells (CSCs) are the origin of cancers. Scientists have identified CSCs in various tumors and have suggested the existence of a variety of states of CSCs. The existence of epithelial–mesenchymal transition (EMT)-
Shaoqiu Zheng, Jing Luo, Shoucheng Xie, Shanming Lu, Qinghua Liu, Huanqin Xiao, Wenjuan Luo, Yanfang Huang, Kun Liu   +8 more
doaj   +2 more sources

Tumor budding correlates with tumor invasiveness and predicts worse survival in pT1 non-muscle-invasive bladder cancer

Scientific Reports, 2021
Tumor budding is defined as a single cell or a cluster of up to 5 tumor cells at the invasion front. Due to the difficulty of identifying patients at high risk for pT1 non-muscle-invasive bladder cancer (NMIBC) and the difficulties in T1 substaging ...
Markus Eckstein, Charlotte Kimmel, Johannes Bruendl, Florian Weber, Stefan Denzinger, Michael Gierth, Maximilian Burger, Arndt Hartmann, Wolfgang Otto, Johannes Breyer   +9 more
doaj   +1 more source

Tumor budding in cervical carcinoma: Associations with some clinical and pathological factors [PDF]

Archive of Oncology, 2021
Background: Tumor budding is recognized as an important independent prognostic factor in colorectal carcinoma. The aim of this study was to evaluate the grade of tumor budding and association with other clinical and pathological features in patients with
Stanulović Nevena, Ivković-Kapicl Tatjana, Mandić Aljoša, Gutić Bojana   +3 more
doaj