Results 1 to 10 of about 2,314,582 (300)
Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment
Scientific Reports, 2017 Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by ...
Lakisha D. Moore-Smith +4 more
doaj +2 more sources
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Objective To explore the mechanism of FGFR3⁃TACC3 (F3⁃T3) fusion gene mediating DNA damage repair through promoting pyruvate kinase M2 (PKM2)'s nuclear translocation in glioblastoma.
REN Xiu⁃de +5 more
doaj +1 more source
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy [PDF]
BioImpacts, 2023 Introduction: T cells that recognize WT1 peptides have been shown to efficiently eliminate WT1-expressing tumor cells. This study was designed to investigate the feasibility of isolating WT1-reactive T cells from peripheral blood mononuclear cells (PBMCs)
Seyed Mostafa Monzavi +7 more
doaj +1 more source
Design and Validation of Experimental Setup for Cell Spheroid Radiofrequency-Induced Heating
Sensors, 2023 While hyperthermia has been shown to induce a variety of cytotoxic and sensitizing effects on cancer tissues, the thermal dose–effect relationship is still not well quantified, and it is still unclear how it can be optimally combined with other treatment
Ioannis Androulakis +7 more
doaj +1 more source
Culturing Mouse Tumor Cells [PDF]
Cold Spring Harbor Protocols, 2015 Genetically engineered mouse models (GEMMs) are attractive for the study of cancer; however, they can be time-consuming and expensive to produce and maintain. Thus, in certain contexts, the use of in vitro culture systems of tumor cells may provide an efficient and effective means to test hypotheses before assessment in or to complement discoveries in ...
Rhim, Andrew D. +2 more
openaire +3 more sources
Why do tumor-infiltrating lymphocytes have variable efficacy in the treatment of solid tumors?
Frontiers in Immunology, 2022 Lymphocytes in tumor tissue are called tumor-infiltrating lymphocytes (TILs), and they play a key role in the control and treatment of tumor diseases.
Biaoru Li
doaj +1 more source
Cells, 2023 Recently, mesenchymal stem cell (MSC) therapies have been questioned as MSCs are capable of both promoting and inhibiting tumorigenesis. Both MSCs and tumor cells replicate to increase their population size; however, MSCs, but not tumor cells, stop ...
Jerry P. Chen +3 more
doaj +1 more source
Biomolecules, 2021 Selection of optimal control samples is crucial in expression profiling tumor samples. To address this issue, we performed microarray expression profiling of control samples routinely used in head and neck squamous cell carcinoma studies: human bronchial
Adam Ustaszewski +7 more
doaj +1 more source
Experimental model of micronodular thymic neoplasm with lymphoid stroma
Thoracic Cancer, 2023 Background Micronodular thymic neoplasm with lymphoid stroma (MNT), a subtype of thymic tumor, is histopathologically characterized by micronodular thymic epithelial cell nests with lymphoid stroma.
Riko Niwa +4 more
doaj +1 more source
Scientific Reports, 2023 Hyperglycemia impairs immune response; however, it remains unknown whether the anti-tumor effects of anti-programmed cell death-1 antibody (PD-1-Ab) treatment are changed in hyperglycemic conditions.
Masaaki Ito +15 more
doaj +1 more source