Results 31 to 40 of about 2,314,582 (300)

Reciprocal complementation of the tumoricidal effects of radiation and natural killer cells. [PDF]

open access: yesPLoS ONE, 2013
The tumor microenvironment is a key determinant for radio-responsiveness. Immune cells play an important role in shaping tumor microenvironments; however, there is limited understanding of how natural killer (NK) cells can enhance radiation effects. This
Kai-Lin Yang   +6 more
doaj   +1 more source

Isolation of Tumor Cell Colonies in Tissue Culture.

open access: yesExperimental Biology and Medicine, 1958
SummaryA procedure is described for isolation of colonies of mammalian cells in tissue culture. Cell lines of a mouse ependymoma obtained in this way differed in growth characteristics, in capacity to grow, in vivo, and in susceptibility to Theiler's GDVII virus.
Harold E. Pearson, Dorothy L. Lagerborg
openaire   +3 more sources

Aligned Nanotopography Promotes a Migratory State in Glioblastoma Multiforme Tumor Cells

open access: yesScientific Reports, 2016
Glioblastoma multiforme (GBM) is an aggressive, Grade IV astrocytoma with a poor survival rate, primarily due to the GBM tumor cells migrating away from the primary tumor site along the nanotopography of white matter tracts and blood vessels.
A. Beliveau   +4 more
semanticscholar   +1 more source

Tumor cell-collagen interactions: Identification and semi-quantitative evaluation of selectively-expressed genes by combination of differential display- and multiplex-PCR

open access: yesBiological Procedures Online, 2003
It is widely acknowledged that the presence of extracellular matrix components as substrates can drastically modulate the phenotype and gene expression of cultured cells, including tumor cells. A number of published reports indicated that substrates made
Sirchia Rosalia   +2 more
doaj   +1 more source

CXCL9 secreted by tumor-associated dendritic cells up-regulates PD-L1 expression in bladder cancer cells by activating the CXCR3 signaling

open access: yesBMC Immunology, 2021
Background Tumor-associated dendritic cells (TADCs) can interact with tumor cells to suppress anti-tumor T cell immunity. However, there is no information on whether and how TADCs can modulate programmed death-ligand 1 (PD-L1) expression by cancer cells.
Weigang Xiu, Jingjing Luo
doaj   +1 more source

Thioglycollate-elicited murine macrophages are cytotoxic to Mycoplasma arginini-infected YAC-1 tumor cells

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Macrophages are important components of natural immunity involved in inhibition of tumor growth and destruction of tumor cells. It is known that these cells can be activated for tumoricidal activity by lymphokines and bacterial products.
F. Ribeiro-Dias   +5 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses.

open access: yesEndocrinology, 1981
Several clonal lines of cultured Leydig tumor cells have been established and characterized in terms of gonadotropin receptors and steroid production. Although freshly isolated cells derived from the M5480P tumor have functional hCG receptors, only two ...
M. Ascoli
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Oxygen-dependent contraction and degradation of the extracellular matrix mediated by interaction between tumor and endothelial cells

open access: yesAIP Advances, 2019
Understanding the mechanisms of cancer development and metastasis requires comprehensive analyses of interactions between normal and tumor cells and the extracellular matrix (ECM) in hypoxic tumor microenvironments.
Daisuke Yoshino, Kenichi Funamoto
doaj   +1 more source

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