Results 51 to 60 of about 26,025 (289)
Cellular Phenotype Plasticity in Cancer Dormancy and Metastasis
Frontiers in Oncology, 2018 Cancer dormancy is a period of cancer progression in which residual tumor cells exist, but clinically remain asymptomatic for a long time, as well as resistant to conventional chemo- and radiotherapies.
Xiao Yang +4 more
doaj +1 more source
Cellular dormancy in minimal residual disease following targeted therapy
Breast Cancer Research, 2021 Background Breast cancer mortality is principally due to tumor recurrence, which can occur following extended periods of clinical remission that may last decades.
Jason R. Ruth +11 more
doaj +1 more source
Tumor Dormancy and Cell Signaling. V. Regrowth of the BCL1 Tumor After Dormancy Is Established [PDF]
Blood, 1997 AbstractThe majority of BALB/c mice immunized with the BCL1 lymphoma-derived idiotype (Id+) IgM and subsequently challenged with BCL1 tumor cells develop a state of tumor dormancy. The vast majority of dormant lymphoma cells are in cell cycle arrest, but there are also residual replicating cells.
E S, Vitetta +9 more
openaire +2 more sources
Minimal Residual Disease, Metastasis and Immunity
Biomolecules, 2021 Progression from localized to metastatic disease requires cancer cells spreading to distant organs through the bloodstream. Only a small proportion of these circulating tumor cells (CTCs) survives dissemination due to anoikis, shear forces and ...
Jordi Badia-Ramentol +3 more
doaj +1 more source
Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy [PDF]
, 2018 Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse ...
Manjili, Masoud H.
core +1 more source
Label-Free Metabolic Classification of Single Cells in Droplets Using the Phasor Approach to Fluorescence Lifetime Imaging Microscopy. [PDF]
, 2019 Characterization of single cell metabolism is imperative for understanding subcellular functional and biochemical changes associated with healthy tissue development and the progression of numerous diseases.
Aghaamoo, Mohammad +4 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
wiley +1 more source
Lung endothelial PEAR1 induces tumor cell dormancy
Molecular CancerSummary In many cancer patients, distant metastases develop after years of dormancy. Understanding how disseminated tumor cells (DTCs), which are often found in proximity to the microvasculature, remain dormant and what regulates their reactivation is ...
Kenneth Anthony Roquid +10 more
doaj +1 more source
Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]
, 2019 This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia +11 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source