Results 31 to 40 of about 26,291 (288)
Head and neck cancer: metronomic chemotherapy [PDF]
, 2015 In the era of personalized medicine, head and neck squamous cell carcinoma (HNSCC) represents a critical oncologic topic. Conventional chemotherapy regimens consist of drugs administration in cycles near or at the maximum tolerated dose (MDT), followed ...
DE FELICE, FRANCESCA +2 more
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Tumor dormancy and immunoescape [PDF]
APMIS, 2008 The role of the immune system in tumor dormancy is now well established. In several experimental models it is possible to induce tumor dormancy in immunocompetent hosts by prior immunization against tumor cells. Equilibrium between immune response and tumor cells leads to long‐term tumor dormancy.
openaire +2 more sources
Redox Control of the Dormant Cancer Cell Life Cycle
Cells, 2021 Following efficient tumor therapy, some cancer cells may survive through a dormancy process, contributing to tumor recurrence and worse outcomes. Dormancy is considered a process where most cancer cells in a tumor cell population are quiescent with no ...
Bowen Li +5 more
doaj +1 more source
The clinical and prognostic use of circulating tumour cells in breast cancer [PDF]
, 2011 Adjuvant therapies such as endocrine or cytotoxic chemotherapy have been demonstrated to improve overall survival in early breast cancer patients.
Payne, Rachel, Payne, Rachel
core +1 more source
The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis [PDF]
, 2020 International ...
Boissan, Mathieu +6 more
core +4 more sources
Microchamber Cultures of Bladder Cancer: A Platform for Characterizing Drug Responsiveness and Resistance in PDX and Primary Cancer Cells. [PDF]
, 2017 Precision cancer medicine seeks to target the underlying genetic alterations of cancer; however, it has been challenging to use genetic profiles of individual patients in identifying the most appropriate anti-cancer drugs. This spurred the development of
Dall'Era, Marc A +9 more
core +2 more sources
HIGD1A-mediated dormancy and tumor survival [PDF]
Molecular & Cellular Oncology, 2015 Solid tumors contain regions of anoxia that are also glucose deprived. How cancer cells survive such extreme conditions remains unclear. Here, we discuss our recent findings that regulation of hypoxia inducible gene domain family member 1 A (HIGD1A) via epigenetic mechanisms during glucose starvation modulates oxygen consumption and reactive oxygen ...
Kurosh, Ameri, Emin, Maltepe
openaire +2 more sources
Frontiers in Oncology, 2021 Parathyroid hormone related protein (PTHrP) is a multifaceted protein with several biologically active domains that regulate its many roles in normal physiology and human disease.
Courtney M. Edwards +4 more
doaj +1 more source
Consensus micro RNAs governing the switch of dormant tumors to the fast-growing angiogenic phenotype. [PDF]
PLoS ONE, 2012 Tumor dormancy refers to a critical stage in cancer development in which tumor cells remain occult for a prolonged period of time until they eventually progress and become clinically apparent.
Nava Almog +8 more
doaj +1 more source
Biology of advanced uveal melanoma and next steps for clinical therapeutics [PDF]
, 2014 Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes.
Bastian, BC +17 more
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