Results 21 to 30 of about 1,368,638 (269)
The Role of Fibroblast Growth Factors in Tumor Growth [PDF]
Current Cancer Drug Targets, 2009 Biological processes that drive cell growth are exciting targets for cancer therapy. The fibroblast growth factor (FGF) signaling network plays a ubiquitous role in normal cell growth, survival, differentiation, and angiogenesis, but has also been implicated in tumor development.
M, Korc, R E, Friesel
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Frontiers in Oncology, 2021 BackgroundStomach adenocarcinoma (STAD) is a common reason for tumor-related fatalities globally, as it results in distant metastasis. Methyltransferase-like 14 (METTL14), a notable RNA N6-adenosine methyltransferase (m6A), plays a significant role in ...
Qi Yao +13 more
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Frontiers in Genetics, 2021 Background: Circular RNAs (circRNAs) have emerged as important regulators in diverse human malignancies, including ovarian cancer (OC). This study was performed to explore the function and regulatory mechanism underlying circ_0013958 in OC progression ...
Yanfei Liang, Kaiyi Meng, Rui Qiu
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Biology Open, 2017 Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is related to numerous pathophysiological events. We previously reported that a RING ubiquitin ligase complex scaffold protein, cullin-3 (CUL3), and one of its adaptor ...
Masashi Maekawa +8 more
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PAQR3 Inhibits Non-small Cell Lung Cancer Growth by Regulating the NF-κB/p53/Bax Axis
Frontiers in Cell and Developmental Biology, 2020 BackgroundThe expression of progestin and adipoQ receptor 3 (PAQR3) is generally downregulated in multiple tumors, which is associated with tumor progression and poor prognosis.MethodsThe clinical value of PAQR3 was analyzed using various databases and ...
Qiang Guo +7 more
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LECT 2 Antagonizes FOXM1 Signaling via Inhibiting MET to Retard PDAC Progression
Frontiers in Cell and Developmental Biology, 2021 Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with minimally effective treatments, highlighting the importance of developing novel biomarkers and therapeutic targets.
Xin Li +7 more
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Cancer Medicine, 2020 According to our previous study, GOLPH3 is markedly up‐expressed in tongue squamous cell carcinoma (TSCC), which is also associated with poor survival. However, it remains unclear about key upstream and downstream mechanisms of GOLPH3.
Shuwei Chen +10 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Mathematical model of tumor growth with migration and proliferation dichotomy [PDF]
Компьютерные исследования и моделирование, 2009 Mathematical model of infiltrative tumour growth taking into account transitions between two possible states of malignant cell is investigated. These transitions are considered to depend on oxygen level in a threshold manner: high oxygen concentration ...
A. V. Kolobov +3 more
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The Universal Dynamics of Tumor Growth [PDF]
Biophysical Journal, 2003 Scaling techniques were used to analyze the fractal nature of colonies of 15 cell lines growing in vitro as well as of 16 types of tumor developing in vivo. All cell colonies were found to exhibit exactly the same growth dynamics-which correspond to the molecular beam epitaxy (MBE) universality class.
Brú, Antonio +4 more
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