Results 171 to 180 of about 463,193 (304)

Exo-nanomaterials in cancer immunotherapy: reprogramming the tumor immune microenvironment. [PDF]

Front Immunol
Fang W, Qiu E, Liu R, Wang S, Wang T, Wang Y.   +5 more
europepmc   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Applying microfluidic technology to interpret the tumor immune microenvironment and cancer immunotherapy. [PDF]

Cancer Biol Med
Chen X, Tan D, Liu S, Luo R, Liu Y, Zhang M, Li S, Xu J.   +7 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

DNA-Loaded Nanoparticles Reprogram the Tumor Immune Microenvironment to Treat Brain Tumors. [PDF]

Small Sci
Yang J, Raj D, Slika H, Shahani A, Cheng L, Jain M, Idnani E, Luly KM, Ruchika F, Kraft C, Eberhart C, Brem H, Tyler B, Green JJ, Tzeng SY.   +14 more
europepmc   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Epigenetic and post-translational regulatory networks of ferroptosis in the tumor immune microenvironment. [PDF]

Exp Hematol Oncol
Du L, Zhang Y, Luo J, He C, Lang J, Cao X.   +5 more
europepmc   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

Role of SERPINA1 in the tumor immune microenvironment of breast cancer and construction of a prognostic model. [PDF]

Discov Oncol
Xia X, Liu J, Liu J, Chen S, Chen Z.
europepmc   +1 more source

Nutritional competition within tumor microenvironment dictates anti-tumor immunity

National Science Review, 2023
Yankang Fei, Xuetao Cao, Juan Liu
openaire   +2 more sources