Results 281 to 290 of about 469,202 (307)
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Germline Genetic Variation Modulates Tumor Immune Microenvironment
Cancer Discovery, 2021Abstract Patient genetic background contributed to antitumor immune responses at molecular and cellular levels.
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Tumor microenvironment, immune response and post-radiotherapy tumor clearance
Clinical and Translational Oncology, 2020Radiotherapy is the treatment of choice for many cancer patients. Residual tumor leads to local recurrence after a period of an equilibrium created between proliferating, quiescent and dying cancer cells. The tumor microenvironment is a main obstacle for the efficacy of radiotherapy, as impaired blood flow leads to hypoxia, acidity and reduced ...
M. I. Koukourakis, A. Giatromanolaki
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Immune-suppressive properties of the tumor microenvironment
Cancer Immunology, Immunotherapy, 2013Solid tumors are more than an accumulation of cancer cells. Indeed, cancerous cells create a permissive microenvironment by exploiting non-transformed host cells. Thus, solid tumors rather resemble abnormal organs composed of the cancerous cells itself and the stroma providing the supportive framework.
Jýrgen C. Becker +3 more
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Cytokines and Immune Response in the Tumor Microenvironment
Journal of Immunotherapy, 2001SUMMARY: Over the last few decades a wealth of evidence has been gathered on the potential role that the immune system (IS) can play in the fight against cancer. Together with cell surface adhesion molecules, cytokines (CKs) mediate the activities of IS cells.
MOCELLIN, SIMONE, WANG E, MARINCOLA FM
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Immune Response and Tumor Microenvironment
Tumor formation and progression are caused by neoplastic cells, which take advantage of interfere with cellular processes that control growth, survival, and division. New research emphasizes the critical role of the tumor microenvironment (TME) in cancer initiation and metastasis, even though genetic and epigenetic changes are well-known malignant ...Vivek Pazhamalai +5 more
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ADAPTIVE IMMUNITY AND THE TUMOR IMMUNE MICROENVIRONMENT
2019The adaptive immune system is essential for production of anti-tumor immune responses, with the majority of current immunotherapeutics designed to modulate the interaction between adaptive immunity and tumor cells within the tumor-immune microenvironment.
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Small-molecule modulators of tumor immune microenvironment
Bioorganic ChemistryIn recent years, tumor immunotherapy, aimed at increasing the activity of immune cells and reducing immunosuppressive effects, has attracted wide attention. Among them, immune checkpoint blocking (ICB) is the most commonly explored therapeutic approach.
Jing Zhang +9 more
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Glutamine and the Tumor Immune Microenvironment
European Urology, 2019Izak, Faiena, Daiki, Ueno, Brian, Shuch
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Tumor microenvironment and immune surveillance
Microenvironment and Microecology Research, 2022openaire +1 more source
Metabolic programming and immune suppression in the tumor microenvironment
Cancer Cell, 2023Emily Arner, Jeffrey C Rathmell
exaly