Prehabilitation as a Biologically Active Intervention Is Associated with the Remodeling of the Pancreatic Tumor-Immune Microenvironment. [PDF]
Stubbins R +9 more
europepmc +1 more source
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Tumor immune microenvironment states inferred from TLS-associated immune-cell composition stratify prognosis in hepatocellular carcinoma. [PDF]
Cheng C +10 more
europepmc +1 more source
<i>CREM</i> regulates the tumor immune microenvironment and predicts prognosis in thyroid carcinoma. [PDF]
Ling H, Wu G, Tang L, Hu Y.
europepmc +1 more source
Hydrogel-Based Immunomodulation of Tumor Immune Microenvironment in Hepatocellular Carcinoma: Current Strategies and Future Directions. [PDF]
Zhang S, Ding L, Hou T, Lin D, Qu Y.
europepmc +1 more source
Multi-platform analysis of the tumor immune microenvironment associated with breast cancer subtypes. [PDF]
Torland LA +14 more
europepmc +1 more source
Irreversible electroporation in prostate cancer: efficacy, tumor immune microenvironment remodeling, and combination immunotherapy-a narrative review. [PDF]
Xiao J +5 more
europepmc +1 more source
Combination of APS, HMGN1, and anti-TNFR2 antibody remodels the tumor immune microenvironment to enhance antitumor immunity in colorectal cancer. [PDF]
Zhao L +8 more
europepmc +1 more source
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Immune checkpoints in the tumor microenvironment
Seminars in Cancer Biology, 2020Interactions between immune checkpoints (ICs) and their ligands negatively regulate T cell activation pathways involved in physiological immune responses against specific antigens. ICs and their ligands are frequently upregulated in the tumor microenvironment (TME) of various malignancies, and they represent significant barriers for induction of ...
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