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Immune Cells Within the Tumor Microenvironment
2013A plethora of intrinsic and extrinsic factors, including communication between tumorigenic cells and infiltrating immune cells, fibroblasts, epithelial cells, vascular and lymphatic endothelial cells, cytokines and chemokines, constitute the tumor microenvironment.
ZOLLO, MASSIMO, SPANO, DANIELA
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Modification of the tumor microenvironment to enhance immunity
Frontiers in Bioscience, 2007The growth and spread of cancer depends as much on the host response to tumor as on the biological characteristics of the tumor itself. This interaction is at its most intimate and dynamic within the tumor microenvironment. It is here that the battle is fought that leads to mutual evolution of tumor and host cell phenotypes.
Yu-Pei, Liao +2 more
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The tumor immune microenvironment in peritoneal carcinomatosis
2022One in four patients with colorectal cancer, 40% of gastric cancer patients, and 60% of ovarian cancer patients will develop peritoneal metastases (PM) in the course of their disease. The outcome of patients with widespread PM remains poor with currently available treatments.
Jesse, Demuytere +4 more
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Immune Cell Metabolism in Tumor Microenvironment
2017Tumor microenvironment (TME) is composed of tumor cells, immune cells, cytokines, extracellular matrix, etc. The immune system and the metabolisms of glucose, lipids, amino acids, and nucleotides are integrated in the tumorigenesis and development. Cancer cells and immune cells show metabolic reprogramming in the TME, which intimately links immune cell
Yongsheng, Li, Yisong Y, Wan, Bo, Zhu
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The Role of Immune Cells in the Tumor Microenvironment
2006Interactions between tumor infiltrating leukocytes and tumor cells have been of great interest because of the possibility that immune cells either interfere with tumor progression or actively promote tumor growth. The tumor microenvironment is shaped by cells entering it, and their functions reflect the local conditions. Successive changes occurring at
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Glutamine and the Tumor Immune Microenvironment
European Urology, 2019Izak, Faiena, Daiki, Ueno, Brian, Shuch
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Metabolic programming and immune suppression in the tumor microenvironment
Cancer Cell, 2023Jeffrey C. Rathmell, Emily Arner
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ADAPTIVE IMMUNITY AND THE TUMOR IMMUNE MICROENVIRONMENT
2019The adaptive immune system is essential for production of anti-tumor immune responses, with the majority of current immunotherapeutics designed to modulate the interaction between adaptive immunity and tumor cells within the tumor-immune microenvironment.
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Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment
Annual Review of Immunology, 2021Yuanyuan Zhang +2 more
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