Results 1 to 10 of about 3,094,522 (302)
hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation
Cells, 2022 Neutrophils are not only crucial immune cells for the neutralization of pathogens during infections, but they are also key players in tissue repair and cancer.
Danique E. M. Duits +7 more
doaj +1 more source
eLife, 2021 Complexes of IL-2 and JES6-1 mAb (IL-2/JES6) provide strong sustained IL-2 signal selective for CD25+ cells and thus they potently expand Treg cells. IL-2/JES6 are effective in the treatment of autoimmune diseases and in protecting against rejection of ...
Jakub Tomala +6 more
doaj +1 more source
Modeling COVID-19 vaccine-induced immunological memory development and its links to antibody level and infectiousness [PDF]
arXiv, 2022 COVID-19 vaccines have proven to be effective against SARS-CoV-2 infection. However, the dynamics of vaccine-induced immunological memory development and neutralizing antibodies generation are not fully understood, limiting vaccine development and vaccination regimen determination. Herein, we constructed a mathematical model to characterize the vaccine-
arxiv
Cell & Bioscience, 2019 Background Babaodan (BBD), a traditional Chinese medicine, has been shown to have protective effects during liver injury and ameliorate liver disease progression, but little is known about its effect on non-alcoholic fatty liver disease (NAFLD).
Dandan Sheng +13 more
doaj +1 more source
Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
Genome BiologyBackground DNA damage tolerance (DDT) enables replication to continue in the presence of fork stalling lesions. In mammalian cells, DDT is regulated by two independent pathways, controlled by the polymerase REV1 and ubiquitinated PCNA, respectively ...
Daniel de Groot +13 more
doaj +1 more source
Cancers, 2023 Simple Summary Diffuse large B-cell lymphoma (DLBCL) is the most common type of malignant lymphoid neoplasm and includes morphologically and molecularly heterogeneous disease subtypes.
Taishi Takahara +3 more
semanticscholar +1 more source
A statistical mechanics approach to autopoietic immune networks [PDF]
, 2010 The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may stem. In order to make theoretical immunology appealing to the statistical physicist audience we are going to ...
arxiv +1 more source
Babao Dan attenuates acute ethanol-induced liver injury via Nrf2 activation and autophagy
Cell & Bioscience, 2019 Background Babao Dan (BBD), a traditional Chinese medicine, has been used as a complementary and alternative medicine to treat multifarious liver diseases.
Yang Yu +9 more
doaj +1 more source
Early Detection and Localization of Pancreatic Cancer by Label-Free Tumor Synthesis [PDF]
arXiv, 2023 Early detection and localization of pancreatic cancer can increase the 5-year survival rate for patients from 8.5% to 20%. Artificial intelligence (AI) can potentially assist radiologists in detecting pancreatic tumors at an early stage. Training AI models require a vast number of annotated examples, but the availability of CT scans obtaining early ...
arxiv
Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities
Frontiers in Immunology, 2017 Vγ9Vδ2-T cells are considered as potent effector cells for tumor immunotherapy through directly killing tumor cells and indirectly regulating other innate and adaptive immune cells to establish antitumoral immunity.
Zheng Xiang, W. Tu
semanticscholar +1 more source