Results 1 to 10 of about 439,426 (292)
High-content CRISPR screening in tumor immunology. [PDF]
Front Immunol, 2022 CRISPR screening is a powerful tool that links specific genetic alterations to corresponding phenotypes, thus allowing for high-throughput identification of novel gene functions.
Holcomb EA +7 more
europepmc +2 more sources
Editorial: New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy. [PDF]
Front Oncol, 2022 Seiffert M, Moussay E, Paggetti J.
europepmc +2 more sources
Distinct blood and visceral adipose tissue regulatory T cell and innate lymphocyte profiles characterize obesity and colorectal cancer [PDF]
, 2017 Visceral adipose tissue (VAT) is a main site where metabolic and immunologic processes interplay to regulate, at local and systemic level, the inflammatory status and immune response.
Barbara Varano +14 more
core +19 more sources
Cell Communication and Signaling, 2023 The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of NKG2D ligands (
Reem Alkhayer +6 more
doaj +1 more source
OncoImmunology, 2023 The clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients have recently spurred the clinical implementation of ICB in the neoadjuvant and perioperative setting. However, how neoadjuvant ICB therapy affects the systemic immune
Olga S. Blomberg +15 more
doaj +1 more source
Immunobiology of solid cancers: cellular and molecular pathways as potential diagnostic and therapeutic targets [PDF]
, 2018 In the last four decades, tumor immunology has shed light on identity and functions of cells and molecules involved in tumor rejection through the involvement of the immune system [1].
Braicu, E. I. +3 more
core +7 more sources
eLife, 2020 Tumor immunology is undergoing a renaissance due to the recent profound clinical successes of tumor immunotherapy. These advances have coincided with an exponential growth in the development of –omics technologies. Armed with these technologies and their
Nathan E Reticker-Flynn +1 more
doaj +1 more source
Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity
Journal of Immunology Research, 2023 Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli +8 more
doaj +1 more source
OncoImmunology, 2021 Cancer-associated fibroblasts (CAFs) and hypoxia are central players in the complex process of tumor cell-stroma interaction and are involved in the alteration of the anti-tumor immune response by impacting both cancer and immune cell populations ...
Linda Ziani +3 more
doaj +1 more source
OncoImmunology, 2023 Natural Killer (NK) cells are important components of the immune system in the defense against tumor growth and metastasis. They release exosomes containing proteins and nucleic acids, including microRNAs (miRNAs).
Anna Laura Di Pace +8 more
doaj +1 more source