Results 1 to 10 of about 3,267,170 (212)
Lipid metabolism in tumor immunology and immunotherapy. [PDF]
Front Oncol, 2023 Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness.
Duong LK +8 more
europepmc +4 more sources
Function of γδ T cells in tumor immunology and their application to cancer therapy. [PDF]
Exp Mol Med, 2021 T cells of the γδ lineage are unconventional T cells with functions not restricted to MHC-mediated antigen presentation. Because of their broad antigen specificity and NK-like cytotoxicity, γδ T-cell importance in tumor immunology has been emphasized ...
Park JH, Lee HK.
europepmc +4 more sources
High-content CRISPR screening in tumor immunology [PDF]
Frontiers in Immunology, 2022 CRISPR screening is a powerful tool that links specific genetic alterations to corresponding phenotypes, thus allowing for high-throughput identification of novel gene functions.
Erin A. Holcomb +16 more
doaj +3 more sources
Journal of Vaccines & Vaccination, 2013 The immune system has effectively evolved to protect the host against foreign invaders, including bacterial, viral, and parasitic infiltrates. Less clear has been the interaction and the protective effects the immune system mounts against its own ...
Mohamed L. Elsaie
semanticscholar +3 more sources
Tumor Immunology and Immunotherapy of Non-Small-Cell Lung Cancer. [PDF]
Cold Spring Harb Perspect Med, 2022 Historically, non-small-cell lung cancer (NSCLC) has been regarded as a nonimmunogenic tumor; however, recent studies have shown that NSCLCs are among the most responsive cancers to monoclonal antibody immune checkpoint inhibitors (ICIs).
Cascone T +3 more
europepmc +4 more sources
Epigenetics of Dendritic Cells in Tumor Immunology. [PDF]
Cancers (Basel), 2022 Simple Summary Dendritic cells (DCs) are an important type of immune cell present in the blood and tissues, capable of detecting potential threats and displaying them to lymphocytes in the lymph nodes, therefore initiating lymphocyte-mediated responses ...
Godoy-Tena G, Ballestar E.
europepmc +4 more sources
Exosome-mediated regulation of tumor immunology. [PDF]
Cancer Sci, 2018 Exosomes are representative extracellular vesicles (EV) derived from multivesicular endosomes (MVE) and have been described as new particles in the communication of neighborhood and/or distant cells by serving as vehicles for transfer between cells of ...
Seo N, Akiyoshi K, Shiku H.
europepmc +4 more sources
Roles for the FCRL6 Immunoreceptor in Tumor Immunology. [PDF]
Front Immunol, 2020 Members of the Fc receptor-like (FCRL1–6) gene family encode transmembrane glycoproteins that are preferentially expressed by B cells and generally repress responses via cytoplasmic tyrosine-based regulation.
Davis RS.
europepmc +4 more sources
In ovo model in cancer research and tumor immunology. [PDF]
Front Immunol, 2022 Considering cancer not only as malignant cells on their own but as a complex disease in which tumor cells interact and communicate with their microenvironment has motivated the establishment of clinically relevant 3D models in past years.
Miebach L, Berner J, Bekeschus S.
europepmc +2 more sources
Lung cancer in never smokers: Tumor immunology and challenges for immunotherapy. [PDF]
Front Immunol, 2022 Lung cancer is the second most common and the most lethal malignancy worldwide. It is estimated that lung cancer in never smokers (LCINS) accounts for 10-25% of cases, and its incidence is increasing according to recent data, although the reasons remain ...
de Alencar VTL +4 more
europepmc +2 more sources