Results 41 to 50 of about 489,862 (290)
Journal of Medical Case Reports, 2022 Background Tumor lysis syndrome is an oncologic emergency that involves multiple metabolic abnormalities and clinical symptoms such as acute renal failure, cardiac arrhythmias, seizures, and multiorgan failure, and may be fatal if not promptly recognized.
Steven N. Luminais +5 more
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Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]
, 2010 Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
Kuçi, Selim +12 more
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Sorafenib-induced tumor lysis syndrome in a patient with metastatic hepatocellular carcinoma ☆
Hematology/Oncology and Stem Cell Therapy, 2020 Tumor lysis syndrome is a potentially lethal complication of chemotherapy, usually associated with aggressive hematologic malignancies. We describe the case of a young patient with metastatic hepatocellular cancer who developed rapid and fatal tumor ...
Sardar Zakariya Imam +2 more
doaj +1 more source
Methods and compositions for stimulating T-lymphocytes [PDF]
, 2003 Disclosed are methods, compositions, antibodies, and therapeutic kits for use in stimulating cytotoxic T-lymphocytes and generating immune responses against epitopes of protooncogenes.
Fisk, Bryan A. +2 more
core +1 more source
Tumor lysis syndrome in pediatric patients with hematological malignancies
Journal of Applied Hematology, 2022 BACKGROUND: Tumor lysis syndrome (TLS) is a common complication of hematological malignancies and consists of either hyperkalemia, hyperphosphatemia, hyperuricemia, or hypocalcemia. These metabolic derangements may result in clinical tumor lysis syndrome
Lamis Hani Elkhatib +5 more
doaj +1 more source
Natural killer (NK) cells and their involvement in different types of cancer. Current status of clinical research [PDF]
, 2017 Natural killer cells are the main agents of innate immunity. Since 1970, various studies have repeatedly confirmed their involvement in decreasing local tumor growth and also decreasing the risk of metastasis, due to their cytotoxic effects and also ...
Moldovan, Adina D. +2 more
core +4 more sources
International Journal of Gerontology, 2014 Tumor lysis syndrome (TLS) is rarely induces after Transarterial chemoembolization for hepatocellular carcinoma. We present a patient with a large hepatocellular carcinoma who received twice transarterial embolization (TAE).
Hsaing-Hung Lin +4 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Fatal tumor lysis syndrome in a patient with metastatic gastric adenocarcinoma
Autopsy and Case Reports, 2021 Tumor lysis syndrome is a well-characterized and potentially deadly complication of spontaneous or treatment-related tumor destruction, and it is most commonly associated with hematologic malignancies.
Robin Moiseff +2 more
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