Results 251 to 260 of about 506,829 (351)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Successful Treatment of Refractory Mucocutaneous Behçet's Disease With Gastrointestinal Involvement Using Anti-tumor Necrosis Factor-Alpha (Anti-TNF-α) Therapy. [PDF]

Cureus
Elfatih Mohamed M, Mazin Al-Issa R, Ahmed H, Emad Al-Zaidy A, Elbadawi F.   +4 more
europepmc   +1 more source

Tumor necrosis factor-alpha antibodies in fistulizing crohn's disease: An updated systematic review and meta-analysis

, 2017
Shekoufeh Nikfar, Pardis Zaboli, Mohammad Abdollahı, Shilan Mozaffari   +3 more
openalex   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

The Impact of Two Cordless Retraction Materials on Inflammatory Biomarkers Interleukin-1 Beta and Tumor Necrosis Factor-Alpha in Gingival Crevicular Fluid: An In-Vivo Study. [PDF]

Cureus
Pidaparthi S, Krishna Kishore K, Surapaneni H, Madhavarapu NP, Sultana N, Adavikatla S, Gupta S.   +6 more
europepmc   +1 more source

Depressive disorder; clinical correlates and tumor necrosis factor alpha among post COVID-19 patients [PDF]

Aya Mohamed Khaled Sakr, Tarek Okasha, Marwa A. Hamed, Maha Mohamed Sayed, Mariam Yehia Mohamed   +4 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Anti-tumor necrosis factor-alpha inhibitor-induced linear psoriasis: A case report. [PDF]

SAGE Open Med Case Rep
MacIntyre OC, Purdy K.
europepmc   +1 more source

Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet

, 2018
Flavia Lambertucci, Ainelén Arboatti, M.G. Sedlmeier, Omar Motiño, María de Luján Álvarez, María Paula Ceballos, Silvina R. Villar, Eduardo Roggero, Juan A. Monti, G Pisani, Ariel D. Quiroga, Paloma Martı́n-Sanz, Cristina E. Carnovale, Daniel E. Francés, Marı́a Teresa Ronco   +14 more
openalex   +2 more sources

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source