Results 281 to 290 of about 501,207 (351)

Transcriptional Activity of Tumor Necrosis Factor Alpha Genes and Their Receptors in Patients with Varying Degrees of Coronary Artery Disease. [PDF]

Int J Mol Sci
Potyka K, Dąbek J.
europepmc   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Serum Vitamin D Level Correlates Significantly With Leptin and Tumor Necrosis Factor-Alpha in Overweight Postmenopausal Women With Hypertension. [PDF]

J Clin Med Res
Qahwaji DM, Serafi AS, Alaamri S, Hussain Z, Bafail MA, Gondi CS, Demirkhanyan L, Waraich RS, Sohail S.   +8 more
europepmc   +1 more source

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

Advanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li, Ruixue Ai, Xinjiani Chen, Yaning Wang, Chenlei Pan, Suxian Song, Chenjie Yang, Yu Zhou, Zhen Zhang, Xiaojun Liu, Xiaodi Liu, Liping Yao, Quanbao Zhang, Wenxue Gu, Rongqing Zhang   +14 more
wiley   +1 more source

Combined effect of micro-osteoperforation and vibration on interleukin-1B, receptor activator of nuclear factor kappa-B ligand, C-C motif chemokine ligand 2, and tumor necrosis factor-alpha in orthodontic patients: A parallel-design randomized clinical trial. [PDF]

Dent Res J (Isfahan)
Gholamrezayi E, Sarmadi S, Samimi SM, Ghadirian H.   +3 more
europepmc   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis. [PDF]

Clin Infect Dis
Hennessee I, Benedict K, Bahr NC, Lipner SR, Gold JAW.   +4 more
europepmc   +1 more source

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Serum tumor necrosis factor-alpha status in hospitalized patients with coronavirus disease-2019 (COVID-19). [PDF]

Caspian J Intern Med
Babaei M, Heidari B, Sadeghi Haddad Zavareh M, Ahmadnia Z, Ghorbani H, Rouhi S.   +5 more
europepmc   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source