Results 31 to 40 of about 5,576,002 (348)

Macrophages promote the progression of premalignant mammary lesions to invasive cancer. [PDF]

, 2017
Breast cancer initiation, progression and metastasis rely on a complex interplay between tumor cells and their surrounding microenvironment. Infiltrating immune cells, including macrophages, promote mammary tumor progression and metastasis; however, less
Anderson, Bissell, Blair, Colombatti, Colombo, Condeelis, Coussens, De Palma, Earp, Ghosh, Green, Gunaratne, Hermoso, Hylton, Jensen, Jirstrom, Lewis, Lidereau, Luo, Lydon, Maatta, Machado, Mantovani, Naber, Naldini, Ochiai, Ochoa, Piemonti, Pollard, Pollard, Pollard, Pollard, Pollard, Porse, Rosen, Rosen, Rosen, Sarukhan, Schwertfeger, Schwertfeger, Shen, Strassmann, Suthipintawong, Ullrich, Van Ginderachter, Van Ginderachter, van Rooijen, Visvader, Wang, West   +49 more
core   +1 more source

The Diverse Roles of Heme Oxygenase-1 in Tumor Progression

Frontiers in Immunology, 2021
Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in response to a variety of stimuli to degrade heme, which generates the biologically active catabolites carbon monoxide (CO), biliverdin and ferrous iron (Fe2+).
K. N. Luu Hoang, Joanne E. Anstee, J. N. Arnold   +2 more
semanticscholar   +1 more source

Dissecting the roles and clinical potential of YY1 in the tumor microenvironment

Frontiers in Oncology, 2023
Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a vital dual biological role in cancer as an oncogene or a tumor suppressor during tumorigenesis and tumor progression.
MengNa Li, MengNa Li, MengNa Li, MengNa Li, JianXia Wei, JianXia Wei, JianXia Wei, ChangNing Xue, ChangNing Xue, ChangNing Xue, XiangTing Zhou, ShiPeng Chen, ShiPeng Chen, ShiPeng Chen, LeMei Zheng, LeMei Zheng, LeMei Zheng, YuMei Duan, YuMei Duan, YuMei Duan, HongYu Deng, HongYu Deng, HongYu Deng, Wei Xiong, Wei Xiong, Wei Xiong, FaQing Tang, GuiYuan Li, GuiYuan Li, GuiYuan Li, Ming Zhou, Ming Zhou, Ming Zhou, Ming Zhou   +33 more
doaj   +1 more source

Roles of IFN-γ in tumor progression and regression: a review

Biomarker Research, 2020
Background Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro-apoptotic and antiproliferative functions, IFN-γ is considered potentially useful
D. Jorgovanović, Mengjia Song, Liping Wang, Yi Zhang   +3 more
semanticscholar   +1 more source

Role of tumor microenvironment in cancer progression and therapeutic strategy

Cancer Medicine, 2023
Cancer is now considered a tumor microenvironment (TME) disease, although it was originally thought to be a cell and gene expression disorder. Over the past 20 years, significant advances have been made in understanding the complexity of the TME and its ...
Qingjing Wang, Xue-ting Shao, Yuxuan Zhang, Miaojin Zhu, F. X. Wang, Jianjian Mu, Jia-Xia li, H. Yao, Keda Chen   +8 more
semanticscholar   +1 more source

Platelets, thrombo-inflammation and cancer

Акушерство, гинекология и репродукция, 2022
It has long been recognized a crucial role played by platelets in thrombosis and hemostasis. Along with that, laboratory and clinical data suggest that platelets contribute to tumor progression and metastasis through a variety of interactions with cancer
E. V. Slukhanchuk, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, A. G. Solopova, V. N. Galkin, A. S. Shkoda, V. I. Tsibizova, V. I. Linnikov, Ismail Elalamy, J.-С. Gris, B. Brenner, A. D. Makatsariya   +12 more
doaj   +1 more source

Neural regulation of cancer: from mechanobiology to inflammation. [PDF]

, 2016
Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung, Rowat, Amy C, Sloan, Erica K   +2 more
core   +2 more sources

Tumor Immune Microenvironment and Its Related miRNAs in Tumor Progression

Frontiers in Immunology, 2021
MiRNA is a type of small non-coding RNA, by regulating downstream gene expression that affects the progression of multiple diseases, especially cancer.
Yangang Xing, G. Ruan, H. Ni, Hai Qin, Simiao Chen, Xin-yue Gu, Jiamin Shang, Yan-tong Zhou, X. Tao, Lufeng Zheng   +9 more
semanticscholar   +1 more source

Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression [PDF]

, 2017
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, liver, colon and pancreas. These cancers are very aggressive and rapidly metastasize, thus identifying effective targets is crucial ...
Bacigalupo, Maria Lorena, Carabias, Pablo, Troncoso, María Fernanda   +2 more
core   +1 more source

Influence of preoperative life satisfaction on recovery and outcomes after colorectal cancer surgery - a prospective pilot study

Health and Quality of Life Outcomes, 2018
Background Colorectal surgery has an important impact on a patient’s quality of life, and postoperative rehabilitation shows large variations. To enhance the understanding of recovery after colorectal cancer, health-related quality of life has become a ...
B. Romain, O. Rohmer, S. Schimchowitsch, M. Hübner, J. B. Delhorme, C. Brigand, S. Rohr, D. Guenot   +7 more
doaj   +1 more source