Disulfidptosis in tumor progression
Cell Death DiscoveryDisulfidptosis, a regulated cell death modality driven by the cystine transporter solute carrier family 7 member 11 (SLC7A11), is characterized by actin cytoskeleton collapse under glucose starvation.
Senlin Wan +10 more
doaj +3 more sources
Dysembryoplastic Neuroepithelial Tumor: A Benign but Complex Tumor of the Cerebral Cortex [PDF]
, 2022 Dysembryoplastic neuroepithelial tumor (DNET) is a distinct type of low-grade glioneuronal tumor. Clinically, DNET is highly associated with intractable epilepsy in young children and adolescents.
김세훈
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Tumor microenvironment and progression [PDF]
Journal of Surgical Oncology, 2011 AbstractTumor blood vessels are heterogeneous, of at least six distinct types, are induced primarily by vascular endothelial growth factor‐A (VEGF‐A), and provide a potentially useful therapeutic target. Breast cancer is characterized by changes in the microenvironment that result in altered tensional homeostasis.
Dvorak, Harold F +3 more
openaire +4 more sources
Fibroblast subsets in intestinal homeostasis, carcinogenesis, tumor progression, and metastasis [PDF]
, 2021 Simple Summary Colorectal cancer often develops via the adenoma-carcinoma sequence, a process which is accompanied by (epi) genetic alterations in epithelial cells and gradual phenotypic changes in fibroblast populations.
Dang, H. +5 more
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Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer [PDF]
, 2013 Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also
Kim, Mia +38 more
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Tetraspanins and tumor progression
Clinical & Experimental Metastasis, 2010 Transmembrane protein tetraspanins either promote or suppress tumor invasion and metastasis. Their effects on tumor progression depend on the multimolecular transmembrane complex called tetraspanin-enriched microdomain (TEM) and are attributed to the alterations in the (1) motogenic and mitogenic behaviors and/or (2) microenvironmental interactions of ...
Richardson, Mekel M. +2 more
openaire +2 more sources
Macrophages in Tumor Microenvironments and the Progression of Tumors [PDF]
Clinical and Developmental Immunology, 2012 Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. Macrophages can be activated by a variety of stimuli and polarized to functionally different phenotypes.
Ning-Bo Hao +5 more
openaire +3 more sources
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages [PDF]
, 2007 Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy.
Pollard, Jeffrey W +7 more
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Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]
, 2012 Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
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Grade Progression and Intrapatient Tumor Heterogeneity as Potential Contributors to Resistance in Gastroenteropancreatic Neuroendocrine Tumors [PDF]
, 2023 Gastroenteropancreatic neuroendocrine neoplasms (NENs) are a heterogenous group of tumors that are incurable when metastatic, regardless of grade. The aim of this article is to understand tumor heterogeneity and grade progression as possible contributors
Emily Bergsland +5 more
core +1 more source