Results 11 to 20 of about 1,149,461 (264)
Disulfidptosis in tumor progression
Cell Death DiscoveryDisulfidptosis, a regulated cell death modality driven by the cystine transporter solute carrier family 7 member 11 (SLC7A11), is characterized by actin cytoskeleton collapse under glucose starvation.
Senlin Wan +10 more
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Tumor microenvironment and progression [PDF]
Journal of Surgical Oncology, 2011 AbstractTumor blood vessels are heterogeneous, of at least six distinct types, are induced primarily by vascular endothelial growth factor‐A (VEGF‐A), and provide a potentially useful therapeutic target. Breast cancer is characterized by changes in the microenvironment that result in altered tensional homeostasis.
Dvorak, Harold F +3 more
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Tetraspanins and tumor progression
Clinical & Experimental Metastasis, 2010 Transmembrane protein tetraspanins either promote or suppress tumor invasion and metastasis. Their effects on tumor progression depend on the multimolecular transmembrane complex called tetraspanin-enriched microdomain (TEM) and are attributed to the alterations in the (1) motogenic and mitogenic behaviors and/or (2) microenvironmental interactions of ...
Richardson, Mekel M. +2 more
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Macrophages in Tumor Microenvironments and the Progression of Tumors [PDF]
Clinical and Developmental Immunology, 2012 Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. Macrophages can be activated by a variety of stimuli and polarized to functionally different phenotypes.
Ning-Bo Hao +5 more
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Tumor progression and metastasis [PDF]
Carcinogenesis, 2000 It is now widely accepted that cancer is attributed to the accumulation of genetic alterations in cells. Thus, to understand the molecular mechanisms of cancer metastasis, it is indispensable to identify the genes whose alterations accumulate during cancer progression as well as the genes whose expression is responsible for the acquisition of ...
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Immunohistochemical Expression of Tensin-4/CTEN in Squamous Cell Carcinoma in Dogs
Veterinary Sciences, 2023 C-terminal tensin-like (tensin-4/TNS4/CTEN) is the fourth member of the tensin family, frequently described as displaying oncological functions, including cellular migration, invasion, adhesion, growth, metastasis, epithelial to mesenchymal transition ...
Alexandra Monteiro +5 more
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Dissecting the roles and clinical potential of YY1 in the tumor microenvironment
Frontiers in Oncology, 2023 Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a vital dual biological role in cancer as an oncogene or a tumor suppressor during tumorigenesis and tumor progression.
MengNa Li +33 more
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Platelets, thrombo-inflammation and cancer
Акушерство, гинекология и репродукция, 2022 It has long been recognized a crucial role played by platelets in thrombosis and hemostasis. Along with that, laboratory and clinical data suggest that platelets contribute to tumor progression and metastasis through a variety of interactions with cancer
E. V. Slukhanchuk +12 more
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Health and Quality of Life Outcomes, 2018 Background Colorectal surgery has an important impact on a patient’s quality of life, and postoperative rehabilitation shows large variations. To enhance the understanding of recovery after colorectal cancer, health-related quality of life has become a ...
B. Romain +7 more
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Antiangiogenic Activity of Chemopreventive Drugs
The International Journal of Biological Markers, 2003 Tumors growing within the host form dynamic aberrant tissue that consists of host components, including the stroma, an expanding vasculature and often chronic inflammation, in addition to the tumor cells themselves.
U. Pfeffer +5 more
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