Results 41 to 50 of about 3,117,179 (310)

Progress in the cryoablation and cryoimmunotherapy for tumor

Frontiers in Immunology, 2023
With the rapid advancement of imaging equipment and minimally invasive technology, cryoablation technology is being used more frequently in minimally invasive treatment of tumors, primarily for patients with early tumors who voluntarily consent to ablation as well as those with advanced tumors that cannot be surgically removed or cannot be tolerated ...
Zenan Chen, Liangliang Meng, Liangliang Meng, Jing Zhang, Xiao Zhang   +4 more
openaire   +3 more sources

Microsatellite instability and mismatch repair deficiency in bladder urothelial carcinoma: a Tunisian single-center study

Journal of the Egyptian National Cancer Institute
Background Microsatellite instability (MSI) and deficiency in the human mismatch repair (MMR) system are critical drivers of genomic instability in various cancers.
Ahlem Bdioui, Mariem Akkari, Maroua Krifa, Yosra Souiden, Ethmane Sleimane, Wafa Mokni, Nada Ben Lazrek, Sarra Mestiri, Sihem Hmissa, Nabiha Missaoui   +9 more
doaj   +1 more source

Inflammation in tumor progression

Folia Pharmacologica Japonica, 2011
転移とは病名であり臨床的知見は大きな価値をもつ．画像診断は転移の空間的情報をもたらすと同時に，その質的な所見は原発巣だけでなく転移巣における組織病理学的知見を支持する．がんの進行は血液・血清学的な変化をもたらし，臨床的に治療の有効性や経過の判断に重要である．この変化する分子や細胞の動態こそが，原発巣が遠隔操作の媒体として遠隔臓器にがん細胞を移動させる手段と考えられる．臨床像に類似性の高い実験動物を利用した転移モデルは存在しないため，樹立された複数の人工的転移系で得られた証拠をもとに多くの転移論が主張されている．われわれの視点もその1つであり，転移臓器における本来の生理的機能の恒常性維持に関与している分子プログラムが原発巣によって質的・量的変化を受けた結果であると考えている．具体的には，肺転移の場合 ...
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer

Journal of Hematology & Oncology, 2019
Background Cell-cell interactions maintain tissue homeostasis and contribute to dynamic alteration of the tumor microenvironment (TME). Communication between cancer and host cells not only promotes advanced disease aggression but also determines ...
Wei-Lun Hwang, Hsin-Yi Lan, Wei-Chung Cheng, Shih-Ching Huang, Muh-Hwa Yang   +4 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins. [PDF]

, 2010
Background Peroxide turnover and signalling are involved in many biological phenomena relevant to human diseases. Yet, all the players and mechanisms involved in peroxide perception are not known.
Muszewska, Anna, Lenart, Anna, Grynberg, Marcin, Pawłowski, Krzysztof, Godzik, Adam, Szczepińska, Teresa   +5 more
core   +2 more sources

Prevalence of Epstein-Barr virus infection in North African cancer patients: a systematic review and meta-analysis protocol

Systematic Reviews
Background Epstein-Barr virus (EBV) is a well-recognized oncogenic virus associated with the development of various malignancies. In North Africa, EBV-related cancers, such as nasopharyngeal carcinoma, gastric cancer, and lymphomas, present a significant
Yosra Souiden, Imen Ayouni, Sarra Mestiri, Sihem Hmissa, Nabiha Missaoui   +4 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source