Results 21 to 30 of about 3,117,179 (310)

"Re-educating" tumor-associated macrophages by targeting NF-kappaB [PDF]

, 2008
The nuclear factor kappaB (NF-kappaB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-kappaB in cancer in maintaining the immunosuppressive phenotype of tumor-associated ...
Balkwill, F.R., Mcneish, I., Kellie A. Charles, Thorsten Hagemann, Robinson, S.C., Hagemann, T, Charles, KA, Balkwill, FR, Hagemann, T., Charles, K.A., Iain McNeish, Kulbe, H., Lawrence, T., McNeish, I, Robinson, SC, Thompson, RG, Hagen Kulbe, Richard G. Thompson, Frances R. Balkwill, Stephen C. Robinson, Toby Lawrence, Thompson, R.G., Lawrence, T, Kulbe, H   +23 more
core   +1 more source

Decoding the Impact of Tumor Microenvironment in Osteosarcoma Progression and Metastasis

, 2023
Osteosarcoma (OS) is a heterogeneous, highly metastatic bone malignancy in children and adolescents. Despite advancements in multimodal treatment strategies, the prognosis for patients with metastatic or recurrent disease has not improved significantly ...
D. Isabel Petrescu, Bikesh K. Nirala, Taku Yamamichi, Tasnuva N. Shafin, Jason T. Yustein   +4 more
core   +1 more source

Prognostic models for early and late tumor progression prediction in nasopharyngeal carcinoma: An analysis of 8292 endemic cases

Cancer Medicine, 2023
Objectives The time for posttreatment tumor progression differs between nasopharyngeal carcinoma (NPC) patients. Herein, we established effective nomograms for predicting early tumor progression (ETP) and late tumor progression (LTP) in NPC patients ...
Lu‐Lu Zhang, Wei‐hong Zheng, Wei‐jie Zhu, Qi‐Ling Deng, Jun‐Ling Peng, Yi‐Yang Li, Ying Sun, Li Lin   +7 more
doaj   +1 more source

Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]

, 2009
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core   +1 more source

Differential Expression of Polyamine Pathways in Human Pancreatic Tumor Progression and Effects of Polyamine Blockade on Tumor Microenvironment

, 2021
Pancreatic cancer is the fourth leading cause of cancer death. Existing therapies only moderately improve pancreatic ductal adenocarcinoma (PDAC) patient prognosis.
Altomare, Deborah A, Dirk Geerts, Otto Phanstiel, Gitto, Sarah B, Phanstiel, Otto, Olive, Kenneth P, Hans Maurer, Nakkina, Sai Preethi, Parikh, Jignesh G, Jignesh Parikh, Pandey, Veethika, Maurer, Hans Carlo, Veethika Pandey, Sai Nakkina, Kenneth Olive, Sarah Gitto, Geerts, Dirk, Deborah Altomare   +17 more
core   +1 more source

Maximum tumor diameter is not an independent prognostic factor in high-risk localized prostate cancer. [PDF]

, 2008
Contains fulltext : 69173.pdf (Publisher’s version ) (Open Access)OBJECTIVES: Previous studies suggest that maximum tumor diameter (MTD) is a predictor of recurrence in prostate cancer (PC).
C. A. Hulsbergen-vandeKaa, Oort, I.M. van, L. A. L. M. Kiemeney, Kok, D.E.G., D. E. G. Kok, van Oort, I.M., I. M. van Oort, Kok, D.E., Kiemeney, L.A.L.M., Hulsbergen-van de Kaa, C.A., Kiemeney, L.A., Oort, I.M., van, Witjes, J.A., J. A. Witjes   +13 more
core   +2 more sources

Immunohistochemical Expression of Tensin-4/CTEN in Squamous Cell Carcinoma in Dogs

Veterinary Sciences, 2023
C-terminal tensin-like (tensin-4/TNS4/CTEN) is the fourth member of the tensin family, frequently described as displaying oncological functions, including cellular migration, invasion, adhesion, growth, metastasis, epithelial to mesenchymal transition ...
Alexandra Monteiro, Leonor Delgado, Luís Monteiro, Isabel Pires, Justina Prada, Teresa Raposo   +5 more
doaj   +1 more source

Dissecting the roles and clinical potential of YY1 in the tumor microenvironment

Frontiers in Oncology, 2023
Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a vital dual biological role in cancer as an oncogene or a tumor suppressor during tumorigenesis and tumor progression.
MengNa Li, MengNa Li, MengNa Li, MengNa Li, JianXia Wei, JianXia Wei, JianXia Wei, ChangNing Xue, ChangNing Xue, ChangNing Xue, XiangTing Zhou, ShiPeng Chen, ShiPeng Chen, ShiPeng Chen, LeMei Zheng, LeMei Zheng, LeMei Zheng, YuMei Duan, YuMei Duan, YuMei Duan, HongYu Deng, HongYu Deng, HongYu Deng, Wei Xiong, Wei Xiong, Wei Xiong, FaQing Tang, GuiYuan Li, GuiYuan Li, GuiYuan Li, Ming Zhou, Ming Zhou, Ming Zhou, Ming Zhou   +33 more
doaj   +1 more source

Mathematical modeling of tumor growth and treatment [PDF]

, 2014
Using mathematical models to simulate dynamic biological processes has a long history. Over the past couple of decades or so, quantitative approaches have also made their way into cancer research.
Chaplain, Mark A. J., Enderling, Heiko
core   +1 more source

Tumor progression and metastasis [PDF]

Carcinogenesis, 2000
It is now widely accepted that cancer is attributed to the accumulation of genetic alterations in cells. Thus, to understand the molecular mechanisms of cancer metastasis, it is indispensable to identify the genes whose alterations accumulate during cancer progression as well as the genes whose expression is responsible for the acquisition of ...
openaire   +2 more sources