Results 161 to 170 of about 304,620 (215)

Tumor suppressor C-RASSF proteins

Cellular and Molecular Life Sciences, 2018
Human genome has ten genes that are collectedly called Ras association domain family (RASSF). RASSF is composed of two subclasses, C-RASSF and N-RASSF. Both N-RASSF and C-RASSF encode Ras association domain-containing proteins and are frequently suppressed by DNA hypermethylation in human cancers. However, C-RASSF and N-RASSF are quite different. Six C-
Hiroaki Iwasa   +2 more
exaly   +3 more sources

Oncoproteins and Tumor Suppressor Proteins in Congenital Sacrococcygeal Teratomas

Pediatric Pathology & Laboratory Medicine: Journal of the Society for Pediatric Pathology, Affiliated With the International Paediatric Pathology Association, 1997
Congenital sacrococcygeal teratoma (SCT) is the most common germ cell tumor of infancy and childhood with a female preponderance. Most SCTs are diagnosed at birth, are benign, and consist of fully differentiated, mature tissues. Tumorigenesis of SCTs remains poorly understood.
Reno Hrašćan   +2 more
exaly   +4 more sources

Cell Adhesion Proteins As Tumor Suppressors

The Journal of Urology, 2002
We summarize recent progress on the role of cell adhesion molecules in biology and discuss the potential application of cell adhesion molecules for managing urological cancer.We comprehensively reviewed the literature from 1982 to 2001, including peer reviewed publications and recent abstracts from national meetings, relevant to cell adhesion molecules
Takatsugu, Okegawa   +3 more
openaire   +2 more sources

The Petinoblastoma Tumor Suppressor Protein

1994
Publisher Summary The studies of retinoblastoma (RB) have been driven by three hypotheses: (1) RB is the suppressor of retinoblastoma and possibly the other types of cancer, (2) RB inhibits proliferation by preventing the transcription of genes critical for cell cycle progression, and (3) the inhibitory function of RB can be neutralized by ...
J Y, Wang, E S, Knudsen, P J, Welch
openaire   +2 more sources

The Tumor Suppressor Protein p16INK4a

Experimental Cell Research, 1997
The tumor suppressor protein p16INK4a (inhibitor of CDK4) is one of the most direct links between cell-cycle control and cancer. The p16INK4a gene is frequently inactivated in human tumors, and inheritance of mutant alleles results in susceptibility to several types of cancer.
openaire   +2 more sources

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