Results 61 to 70 of about 3,141,404 (351)

Clinical Aspects of Feline Retroviruses: A Review [PDF]

, 2012
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease.
Katrin Hartmann, Hartmann, Katrin
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A Novel Mechanism of Resistance to Mouse Mammary Tumor Virus Infection [PDF]

Journal of Virology, 2000
ABSTRACTExogenous mouse mammary tumor virus (MMTV) is carried from the gut of suckling pups to the mammary glands by lymphocytes and induces mammary gland tumors. MMTV-induced tumor incidence in inbred mice of different strains ranges from 0 to as high as 100%.
openaire   +2 more sources

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda, Dimmock Nigel J., Dove, Brian K., Scott, P. D. (Paul D.), Carroll, Miles W., Linda Cheung, Miles W Carroll, Brian K Dove, Dove Brian K., Taylor Irene, Bassam Hallis, Meng, Bo, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Miles W. Carroll (111071), Dimmock, N. J., Linda Cheung (71020), Andrew J. Easton (111072), Irene Taylor (111066), Scott Paul D., Bo Meng (111065), Hallis Bassam, Taylor, Irene, Andrew J Easton, Paul D Scott, Bo Meng, Brian K. Dove (111063), Meng Bo, Paul D. Scott (111064), Nigel J Dimmock, Marriott Anthony C., Irene Taylor, Anthony C Marriott, Nigel J. Dimmock (111061), Carroll Miles W., Cheung Linda, Bassam Hallis (111069), Easton Andrew J., Anthony C. Marriott (111070)   +39 more
core   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

Cancer Reports
Background Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. Mutations in oncogenes and tumor suppressor genes provide valuable insights into the molecular mechanisms of ...
Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu   +13 more
doaj   +1 more source

C-Terminal Binding Protein: Regulator between Viral Infection and Tumorigenesis

Viruses
C-terminal binding protein (CtBP), a transcriptional co-repressor, significantly influences cellular signaling, impacting various biological processes including cell proliferation, differentiation, apoptosis, and immune responses.
Meihui Huang, Yucong Li, Yuxiao Li, Shuiping Liu   +3 more
doaj   +1 more source

MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. [PDF]

, 2009
Human infections with highly pathogenic avian influenza viruses of the H5N1 subtype, frequently reported since 2003, result in high morbidity and mortality.
Sutter, G. (Gerd), Sutter Gerd, Rimmelzwaan, Guus F., Osterhaus, A.D.M.E. (Albert), Yasemin Suezer, Gerrie de Mutsert, Suezer, Yasemin, Geert van Amerongen, Löwer, Johannes, Fouchier Ron A. M., Osterhaus, Albert D. M. E., Kreijtz, Joost H. C. M., Mutsert, Gerrie de, Fouchier, Ron A. M., Fouchier, R.A.M. (Ron), Guus F Rimmelzwaan, van den Brand Judith M. A., Löwer Johannes, Johannes Löwer, Kreijtz, J.H.C.M. (Joost), Suezer, Y., Judith M A van den Brand, Suezer Yasemin, Mutsert, G. (Gerrie) de, Amerongen, G. (Geert) van, Rimmelzwaan Guus F., Brand, J.M.A. (Judith) van den, Joost H C M Kreijtz, Sutter, Gerd, Schwantes, Astrid, de Mutsert Gerrie, Brand, Judith M. A. van den, Osterhaus Albert D. M. E., Schwantes Astrid, Scwantes, A. (Astrid), Ron A M Fouchier, van Amerongen Geert, Albert D M E Osterhaus, Gerd Sutter, Astrid Schwantes, Rimmelzwaan, G.F. (Guus), Kreijtz Joost H. C. M., Amerongen, Geert van, Löwer, J., Fouchier, Ron A.M.; id_orcid, Scwantes, Astrid, van Amerongen, Geert, van den Brand, Judith M.A., Osterhaus, Albert D.M.E., Kreijtz, Joost H.C.M., de Mutsert, Gerrie   +50 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]

, 2002
In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Cate, Hugo ten, Djokomoeljanto, Robert J., Gorp , Eric C.M. van, Dolmans, Wil M.V., Hack, C. Erik, Suharti, Catharina, Meer, Jos W.M. van der, Setiati , Tatty E.   +7 more
core   +2 more sources