Results 51 to 60 of about 269,778 (316)

Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.

PLoS Pathogens, 2011
Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46, and they infect activated lymphocytes, dendritic cells, and macrophages via ...
Ryan S Noyce, Daniel G Bondre, Michael N Ha, Liang-Tzung Lin, Gary Sisson, Ming-Sound Tsao, Christopher D Richardson   +6 more
doaj   +1 more source

Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]

, 2012
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David, Richard E. Randall, Richard E. Randall (190211), Nash, A.A., Anthony A Nash, Hoeve, M.A., Marieke A Hoeve, Anthony A. Nash, Hoeve Marieke A., Nash, Anthony A., Dransfield, I., Marieke A. Hoeve (190207), David Jackson (84936), Richard E Randall, Randall Richard E., Jackson, David, Randall, R.E., Nash Anthony A., David Jackson, Jackson, D., Ian Dransfield (190213), Dransfield, Ian, Marieke A. Hoeve, Anthony A. Nash (190209), Randall, Richard E., Ian Dransfield, Hoeve, Marieke A., Dransfield Ian   +27 more
core   +1 more source

The Role of HLA-G in Human Papillomavirus Infections and Cervical Carcinogenesis

Frontiers in Immunology, 2020
Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low polymorphism frequency, restricted tissue distribution and immunoinhibitory property.
Hui-Hui Xu, Wei-Hua Yan, Aifen Lin
doaj   +1 more source

Examining the role of EGR1 during viral infections

Frontiers in Microbiology, 2022
Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array of stimuli such as exposure to growth factors, cytokines, apoptosis, and
Caitlin M. Woodson, Caitlin M. Woodson, Kylene Kehn-Hall, Kylene Kehn-Hall   +3 more
doaj   +1 more source

Virus demyelination [PDF]

, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source

Diagnosis and Neurosurgical Management of Cerebral Nocardiosis

Journal of Neurological Surgery Reports, 2021
Primary Nocardia infections are uncommon gram-positive bacterial infections caused by aerobic actinomycetes and are typically regarded as opportunistic infections (only one-third of infected patients are immunocompetent).
Carley Karam, Abdolreza Siadati
doaj   +1 more source

A Novel Mechanism of Resistance to Mouse Mammary Tumor Virus Infection [PDF]

Journal of Virology, 2000
ABSTRACTExogenous mouse mammary tumor virus (MMTV) is carried from the gut of suckling pups to the mammary glands by lymphocytes and induces mammary gland tumors. MMTV-induced tumor incidence in inbred mice of different strains ranges from 0 to as high as 100%.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection

Molecular Therapy, 2009
Preferential killing of transformed cells, while keeping normal cells and organs unharmed, is the main goal of cancer gene therapy. Genetically engineered trackable markers and imaging reporters enable noninvasive monitoring of transduction efficiency and pharmacokinetics of anticancer virotherapeutics.
Iankov, Ianko D, Hillestad, Matthew L, Dietz, Allan B, Russell, Stephen J, Galanis, Evanthia   +4 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source