Prevalence and Viral Load Determination of BK Polyomavirus among Iranian Patients with Brain Tumors
Background: Due to persistent infections of human central nervous system (CNS), polyomaviruses have been identified as one of the risk factors for brain tumor development.
Saghar Saber Amoli +6 more
doaj
Cutaneous smooth muscle tumors associated with Epstein-Barr virus in an adult patient with HIV, [PDF]
Epstein Barr virus-associated smooth muscle tumors are an uncommon neoplasm that occurs in immunosuppressed patients of any age. Usually, it presents as multifocal tumors mainly in the spinal cord, epidural region, gastrointestinal tract and liver, upper
Estefania Galeano-Piedrahita +3 more
doaj +1 more source
CD8+ T-cell responses in vaccination: Reconsidering targets and function in the context of chronic antigen stimulation [PDF]
Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell-based vaccines.
Cosma, Gabriela L., Eisenlohr, Laurence
core +2 more sources
Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P. +4 more
core +2 more sources
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46, and they infect activated lymphocytes, dendritic cells, and macrophages via ...
Ryan S Noyce +6 more
doaj +1 more source
The Role of HLA-G in Human Papillomavirus Infections and Cervical Carcinogenesis
Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low polymorphism frequency, restricted tissue distribution and immunoinhibitory property.
Hui-Hui Xu, Wei-Hua Yan, Aifen Lin
doaj +1 more source
HIV-1 Evolutionary Patterns Associated with Metastatic Kaposi's Sarcoma during AIDS. [PDF]
Kaposi's sarcoma (KS) in HIV-infected individuals can have a wide range of clinical outcomes, from indolent skin tumors to a life-threatening visceral cancer. KS tumors contain endothelial-related cells and inflammatory cells that may be HIV-infected. In
Barbier, Andrew E +6 more
core +4 more sources
Examining the role of EGR1 during viral infections
Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array of stimuli such as exposure to growth factors, cytokines, apoptosis, and
Caitlin M. Woodson +3 more
doaj +1 more source
Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection
Preferential killing of transformed cells, while keeping normal cells and organs unharmed, is the main goal of cancer gene therapy. Genetically engineered trackable markers and imaging reporters enable noninvasive monitoring of transduction efficiency and pharmacokinetics of anticancer virotherapeutics.
Iankov, Ianko D +4 more
openaire +2 more sources
Diagnosis and Neurosurgical Management of Cerebral Nocardiosis
Primary Nocardia infections are uncommon gram-positive bacterial infections caused by aerobic actinomycetes and are typically regarded as opportunistic infections (only one-third of infected patients are immunocompetent).
Carley Karam, Abdolreza Siadati
doaj +1 more source

