Results 41 to 50 of about 3,141,404 (351)

Oncogenic viruses and their role in oral cavity and oropharyngeal squamous cell carcinoma: a systematic review

Frontiers in Oncology
Oral cavity (OC) and oropharyngeal (OP) squamous cell carcinoma (SCC) represent a major global health concern, accounting for most of head and neck malignancies. These tumors arise from the epithelial lining of the OC and oropharynx and are characterized
Juan Manuel Quiroga-Garza, Maria Fernanda Herrera-Saldivar, Norma Carolina Hernandez-Bautista, Alondra Yamileth Alanis-Valdez, Aldo Sebastian Flores-Flores, Jose Manuel Vazquez-Guillen, Diana Resendez-Perez, Reyes S. Tamez-Guerra, Cristina Rodriguez-Padilla   +8 more
doaj   +1 more source

Human immunodeficiency virus p24 antigen and antibody, herpes simplex virus-2 IgM and tumor necrosis factor alpha plasma levels in adult female children living in single-parent households: a case-control observational study

Journal of Bio-X Research, 2022
. Objective:. Human immunodeficiency virus (HIV) p24 antigen and antibody and herpes simplex virus 2 IgM are seromarkers indicating infection with HIV and herpes simplex virus-2 (HSV-2), respectively, whereas tumor necrosis factor α is an inflammatory ...
Mathew Folaranmi Olaniyan, Tolulope Busayo Olaniyan   +1 more
doaj   +1 more source

The natural history of respiratory syncytial virus in a birth cohort : the influence of age and previous infection on reinfection and disease [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Medley, GF, Ochola, R., Nokes, D. James, Sande, CJ, Nokes, DJ, Ochola, R, Bottomley, C., Ohuma, EO, Okiro, E. A., Medley, Graham, Sande, C. J., Cane, Patricia, Okiro, EA, Ohuma, E. O., Cane, PA   +15 more
core   +1 more source

Germ cell tumors in patients infected by the human immunodeficiency virus [PDF]

Cancer, 2001
The objective of this study was to assess the natural history of the two disease courses, patient immune system tolerance, and results of therapy in human immunodeficiency virus (HIV)-infected patients with germ cell tumors (GCT).From 1985 to 1996, 34 HIV-infected men received a diagnosis of GCT.
K, Fizazi, R J, Amato, P, Beuzeboc, N, Petit, D, Bouhour, A, Thiss, C, Rebischung, C, Chevreau, C J, Logothetis, J P, Droz   +9 more
openaire   +2 more sources

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn, Nicole L. Edworthy, Andrew J. Easton, Meng, Bo, Easton, A. J. (Andrew J.), Bo Meng, Scott, P. D. (Paul D.), Marriott, Anthony C., Anthony C. Marriott, Nigel J. Dimmock, Dimmock, N. J., Paul D. Scott   +11 more
core   +1 more source

Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.

PLoS Pathogens, 2011
Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46, and they infect activated lymphocytes, dendritic cells, and macrophages via ...
Ryan S Noyce, Daniel G Bondre, Michael N Ha, Liang-Tzung Lin, Gary Sisson, Ming-Sound Tsao, Christopher D Richardson   +6 more
doaj   +1 more source

Impaired antibody response causes persistence of prototypic T cell-contained virus [PDF]

, 2009
CD8 T cells are recognized key players in control of persistent virus infections, but increasing evidence suggests that assistance from other immune mediators is also needed. Here, we investigated whether specific antibody responses contribute to control
André Fitsche, Bruno Eschli, Lukas Flatz, Senn, Beatrice M., Marylise Fernandez, Ahmed N Hegazy, Verbeek, J Sjef, Eschli, Bruno, Fink, Katja, Rami Sommerstein, Doron Merkler, Daniel D Pinschewer, Katja Fink, Siegrist, Claire-Anne, Odermatt, Bernhard, Andreas Bergthaler, Horvath, Edit, Fitsche, André, Bergthaler, Andreas, Claire-Anne Siegrist, Holdener, Martin, Beatrice M Senn, Verbeek, J. Sjef, Admar Verschoor, J Sjef Verbeek, Verschoor, Admar, Merkler, Doron, Edit Horvath, Pinschewer, Daniel, Martin Holdener, Bernhard Odermatt, Flatz, Lukas, Pinschewer, Daniel D., Sommerstein, Rami, Hegazy, Ahmed N., Fernandez, Marylise   +35 more
core   +1 more source

Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection

Molecular Therapy, 2009
Preferential killing of transformed cells, while keeping normal cells and organs unharmed, is the main goal of cancer gene therapy. Genetically engineered trackable markers and imaging reporters enable noninvasive monitoring of transduction efficiency and pharmacokinetics of anticancer virotherapeutics.
Iankov, Ianko D, Hillestad, Matthew L, Dietz, Allan B, Russell, Stephen J, Galanis, Evanthia   +4 more
openaire   +2 more sources

Vaccinia virus expressing ICP47 : a novel platform for cancer vaccines highlighting tumor epitopes and hiding viral antigens [PDF]

, 2010
Background Recombinant poxviruses expressing tumor associated antigens (TAAs) are evaluated since 20 years as immunogenic vaccine vector in clinical trials.
Raafat, Nermin Abdel Fattah
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source