Results 41 to 50 of about 267,504 (167)

The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46

Blood, 2004
AbstractThe destruction of viral-infected and tumor cells is mediated in part via the lysis receptor of natural killer (NK) cells, NKp46. The nature, however, of its lysis ligands expressed on target cells is poorly defined. Recently, we have identified a novel functional interaction between the lysis receptors NKp46 and NKp44 and the hemagglutinin of ...
Arnon, T, Achdout, H, Lieberman, N, Gazit, R, Gonen-Gross, T, Katz, G, Bar-Ilan, A, Bloushtain, N, Lev, M, Joseph, A, Kedar, E, Porgador, A, Mandelboim, O   +12 more
openaire   +2 more sources

An optimized protocol for the generation of HBV viral antigen-specific T lymphocytes from pluripotent stem cells

STAR Protocols, 2021
Summary: In T cell-based cancer immunotherapy, tumor antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) can specifically target tumor Ags on malignant cells.
Mohammad Haque, Xiaofang Xiong, Fengyang Lei, Jugal Kishore Das, Jianxun Song   +4 more
doaj   +1 more source

High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

Cancer Reports
Background Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. Mutations in oncogenes and tumor suppressor genes provide valuable insights into the molecular mechanisms of ...
Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu   +13 more
doaj   +1 more source

C-Terminal Binding Protein: Regulator between Viral Infection and Tumorigenesis

Viruses
C-terminal binding protein (CtBP), a transcriptional co-repressor, significantly influences cellular signaling, impacting various biological processes including cell proliferation, differentiation, apoptosis, and immune responses.
Meihui Huang, Yucong Li, Yuxiao Li, Shuiping Liu   +3 more
doaj   +1 more source

Chicken industry strategies for control of tumor virus infections

Poultry Science, 1998
Marek's disease (MD) and lymphoid leukosis (LL) are two distinct viral diseases that cause tumor mortality in chickens. Marek's disease, being horizontally transmitted, is controlled through biosecurity measures and vaccination. Prevention of early exposure before vaccine immunity is established is most important.
openaire   +2 more sources

The Differentiation and Protective Function of Cytolytic CD4 T Cells in Influenza Infection

Frontiers in Immunology, 2016
CD4 T cells that recognize peptide antigen in the context of Class II MHC can differentiate into various subsets that are characterized by their helper functions.
Deborah M. Brown, Anna T. Lampe, Aspen M. Workman   +2 more
doaj   +1 more source

Hepatitis C virus infection triggers a tumor‐like glutamine metabolism [PDF]

Hepatology, 2017
Chronic infection with hepatitis C virus (HCV) is one of the main causes of hepatocellular carcinoma. However, the molecular mechanisms linking the infection to cancer development remain poorly understood. Here we used HCV‐infected cells and liver biopsies to study how HCV modulates the glutaminolysis pathway, which is known to play an important role ...
Levy, P.L., Duponchel, S., Eischeid, H., Molle, Jennifer, Michelet, M., Diserens, G., Vermathen, M., Vermathen, P., Dufour, J.F., Dienes, H.P., Steffen, H.M., Odenthal, M., Zoulim, F., Bartosch, B.   +13 more
openaire   +4 more sources

In vitro infectivity assay for mouse mammary tumor virus. [PDF]

Proceedings of the National Academy of Sciences, 1979
Studies of mouse mammary tumor virus (MMTV) have been impeded by the lack of an in vitro infectivity assay. We have developed a rapid, quantitative in vitro assay for MMTV infectivity based on the detection of positively staining foci by immunoperoxidase.
Vacquier, J P, Cardiff, R D
openaire   +2 more sources

Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication

Frontiers in Immunology, 2022
Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent ...
Shuang Tang, Jie Li, Yung-Fu Chang, Wencheng Lin   +3 more
doaj   +1 more source

NK cells and gammadelta T cells mediate resistance to polyomavirus-induced tumors. [PDF]

PLoS Pathogens, 2010
NK and gammadelta T cells can eliminate tumor cells in many experimental models, but their effect on the development of tumors caused by virus infections in vivo is not known.
Rabinarayan Mishra, Alex T Chen, Raymond M Welsh, Eva Szomolanyi-Tsuda   +3 more
doaj   +1 more source