Results 21 to 30 of about 369,607 (317)

Hepatitis C virus infection triggers a tumor‐like glutamine metabolism [PDF]

Hepatology, 2017
Chronic infection with hepatitis C virus (HCV) is one of the main causes of hepatocellular carcinoma. However, the molecular mechanisms linking the infection to cancer development remain poorly understood. Here we used HCV‐infected cells and liver biopsies to study how HCV modulates the glutaminolysis pathway, which is known to play an important role ...
Levy, P.L., Duponchel, S., Eischeid, H., Molle, Jennifer, Michelet, M., Diserens, G., Vermathen, M., Vermathen, P., Dufour, J.F., Dienes, H.P., Steffen, H.M., Odenthal, M., Zoulim, F., Bartosch, B.   +13 more
openaire   +4 more sources

Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters [PDF]

, 2014
Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Steven J. Halvorson, Nadim J. Ajami, Corey W. Hecksel, Jody L. Swain, Connie Wong, Janet S. Butel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States
Ajami, Nadim J., Butel, Janet S., Chen, Chun Jung, Halvorson, Steven J., Hecksel, Corey W., Sroller, Vojtech, Sullivan, Christopher S., Swain, Jody L., Wong, Connie, Zanwar, Preeti, Zhang, Shaojie   +10 more
core   +3 more sources

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology [PDF]

, 2020
Combination immunotherapy (CIT) is currently applied as a treatment for different cancers and is proposed as a cure strategy for chronic viral infections. Whether such therapies are efficient during an acute infection remains elusive.
Akhmetzyanova, Ilseyar [u.v.m.], David, Paul David, Drabczyk-Pluta, Malgorzata, Gruber, Achim D., Honke, Nadine, Kershaw, Olivia, Knuschke, Torben, Megger, Dominik A., Pastille, Eva, Werner, Tanja   +9 more
core   +1 more source

Avaliação da eficácia do cidofovir na papilomatose respiratória recorrente juvenil Efficacy of cidofovir in recurrent juvenile respiratory papillomatosis

Brazilian Journal of Otorhinolaryngology, 2010
O uso do cidofovir para papilomatose respiratória recorrente juvenil (PRRJ) ainda não tem estudos caso-controle suficientes que comprovem sua eficácia em literatura. OBJETIVO: Avaliar fatores que influenciem o prognóstico da PRRJ, e observar a atuação do
Fabiana Valera, Lucas Maldonato, Jessé Lima, Daniel S Küpper, Rodrigo N Lacerda, Rui Mamede, Hilton Ricz   +6 more
doaj   +1 more source

Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]

, 2014
Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham, Ahmadzadeh, Akbar, Anderson, Baine, Barber, Baur, Belkaid, Bensinger, Bergmann, Berzofsky, Blackburn, Brooks, Brooks, Brooks, Colonna, Das, Day, Duraiswamy, Ejrnaes, Frebel, Geijtenbeek, Guidotti, Ha, Jerome, Jung, Kasprowicz, Kaufmann, Kim, Klein, Kroemer, Kroy, Larsson, Liu, Lu, Maizels, Malek, Matsuzaki, Mier, Mumprecht, Nandedkar, Nurieva, Nurieva, Ramsay, Schietinger, Schwartz, Sofra, Soldaini, Steinman, Trautmann, Vezys, Waggoner, Wedemeyer, Wilson, Yi, Zhou   +55 more
core   +2 more sources

DNA in Uninfected and Virus-Infected Cells Complementary to Avian Tumor Virus RNA [PDF]

Proceedings of the National Academy of Sciences, 1971
The 70S RNA component of several avian tumor viruses was hybridized with DNA extracted from avian tumor virus-infected and uninfected chicken and Japanese quail cells. Tritium-labeled 70S RNAs from Rous sarcoma virus (RSV), Rous associated virus-1 (RAV-1), RAV-60, and Schmidt-Ruppin-RSV (SR-RSV) hybridize from 3 to 10 times more with DNA ...
P N, Rosenthal, H L, Robinson, W S, Robinson, T, Hanafusa, H, Hanafusa   +4 more
openaire   +2 more sources

How Human Tumor Viruses Make Use of Autophagy

Cells, 2012
Viruses commandeer regulatory pathways of their hosts to optimize their success as cellular parasites. The human tumor viruses, Epstein-Barr Virus (EBV), Kaposi’s Sarcoma Herpesvirus (KSHV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) all affect
Bill Sugden, Zachary L. Pratt
doaj   +1 more source

Adverse reactions of biological therapies in patients with psoriasis [PDF]

, 2017
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R., Limbău, Alexandra M., Mitran, Cristina I., Mitran, Mădălina I., Sârbu, Maria I., Tampa, Mircea   +5 more
core   +4 more sources

Number of Virus Particles in Insects and Plants Infected with Wound Tumor Virus [PDF]

Journal of Virology, 1968
A new procedure for counting virus particles was employed to measure the concentration of wound tumor virus in purified virus preparations, in plant tumors, and in the insect vector. Partially purified wound tumor virus was used to establish the quantitative features of the method. A 1-g amount of plant tumor tissue contained an average of
G, Streissle, V, Bystricky, R R, Granados, K, Strohmaier   +3 more
openaire   +2 more sources

PKR induces TGF-β and limits oncolytic immune therapy

Journal for ImmunoTherapy of Cancer, 2023
Background Mammalian cells have developed multiple intracellular mechanisms to defend against viral infections. These include RNA-activated protein kinase (PKR), cyclic GMP-AMP synthase and stimulation of interferon genes (cGAS-STING) and toll-like ...
Balveen Kaur, Guangsheng Pei, Zhongming Zhao, Jianhua Yu, Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Yuanqing Yan, Yoshihiro Otani, Yeshavanth Banasavadi-Siddegowda, Huihui Fan, Michael A Caligiuri   +12 more
doaj   +1 more source