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How Human Tumor Viruses Make Use of Autophagy
Viruses commandeer regulatory pathways of their hosts to optimize their success as cellular parasites. The human tumor viruses, Epstein-Barr Virus (EBV), Kaposi’s Sarcoma Herpesvirus (KSHV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) all affect
Bill Sugden, Zachary L. Pratt
doaj +1 more source
DNA in Uninfected and Virus-Infected Cells Complementary to Avian Tumor Virus RNA [PDF]
The 70S RNA component of several avian tumor viruses was hybridized with DNA extracted from avian tumor virus-infected and uninfected chicken and Japanese quail cells. Tritium-labeled 70S RNAs from Rous sarcoma virus (RSV), Rous associated virus-1 (RAV-1), RAV-60, and Schmidt-Ruppin-RSV (SR-RSV) hybridize from 3 to 10 times more ...
P N, Rosenthal +4 more
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Infective Substructures of Sendai Virus from Infected Ehrlich Ascites Tumor Cells [PDF]
Increase of infectivity for embryonated eggs was observed in Ehrlich ascites tumor cells after intraperitoneal inoculation of Sendai virus into tumor-bearing mice. Virus-induced actinomycin-resistant ribonucleic acid consisting of 14 S , 18 S , 22 S , 35 S
A G, Bukrinskaya +3 more
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Tumorigenesis related to retroviral infections
Retroviral infections are considered important risk factors for cancer development in humans since approximately 15-20% of cancer worldwide is caused by an infectious agent.
Maria Braoudaki +1 more
doaj +1 more source
HIV and intestinal parasite co-infections among a Chinese population : an immunological profile [PDF]
Parasite infections often result in a switch of the human body's predominant immune reaction from T-helper 1 (Th1)-type to Th2-type. Hence, parasite infections are widely expected to accelerate the progression of human immunodeficiency virus (HIV ...
Wang, Feng-Feng +19 more
core +1 more source
Optineurin negatively regulates the induction of IFNβ in response to RNA virus infection [PDF]
The innate immune response provides a critical defense against microbial infections, including viruses. These are recognised by pattern recognition receptors including Toll-like receptors (TLRs) and RIG-I like helicases (RLHs).
Harris, M. +42 more
core +1 more source
Background: Viral cause of sporadic breast cancer (SBC) has been suggested based on the experimental murine model of mammary tumor caused by mouse mammary tumor virus (MMTV), Epstein-Barr virus (EBV), and human papillomavirus (HPV).
Mohammad Al Hamad +9 more
doaj +1 more source
LCVM infection generates tumor antigen-specific immunity and inhibits growth of nonviral tumors
Antibodies and T cells specific for tumor-associated antigens (TAA) are found in individuals without cancer but with a history of infections and are associated with lowered cancer risk.
Camille Jacqueline +5 more
doaj +1 more source
PKR induces TGF-β and limits oncolytic immune therapy
Background Mammalian cells have developed multiple intracellular mechanisms to defend against viral infections. These include RNA-activated protein kinase (PKR), cyclic GMP-AMP synthase and stimulation of interferon genes (cGAS-STING) and toll-like ...
Balveen Kaur +12 more
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The role of viruses in the cancerogenesis
It is estimated that seven key viruses such as Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human T-lymphotropic virus (HTLV), Human papilloma viruses (HPV), Kaposi’s sarcoma-associated herpes-virus (KSHV), Epstein-Barr virus (EBV) and Merkel cell ...
Michał Chojnicki +4 more
doaj +1 more source

