Results 11 to 20 of about 269,778 (316)

Chronic viral infections and their role in shaping the tumor immune microenvironment [PDF]

Frontiers in Immunology
Chronic viral infections, such as HBV, HCV, EBV, and HPV, contribute to tumorigenesis not only through direct oncogenic effects but also by reshaping the tumor immune microenvironment (TIME) via complex immunoregulatory mechanisms.
Huizi Li, Xiulin Jiang, Quanan Zhang, Yihang Yuan   +3 more
doaj   +2 more sources

Virus-driven remodeling of the immune microenvironment and response to immune checkpoint inhibitors: the infection– immunity–cancer crosstalk [PDF]

Frontiers in Immunology
Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic landscape of diverse solid tumors; however, concurrent viral infections significantly influence their efficacy and safety profiles. By driving persistent antigen exposure, inducing T
Guangying Wang, Feiyin Chen, Runda Zhao, Zhuoqi Liu, Zhuoqi Liu, Zhuoqi Liu, Xiaohong Yang, Xiaohong Yang, Xiaohong Yang, Daya Luo, Daya Luo, Daya Luo   +11 more
doaj   +2 more sources

A Viral Protein Antagonist for Both AID and APOBEC3 [PDF]

Viruses
The APOBEC family of cytidine deaminases is part of the innate immune response to infections by multiple RNA- and DNA-containing viruses. Since the activity of these enzymes, typically APOBEC3, often involves mutations that inhibit or block viral ...
Jaquelin P. Dudley
doaj   +2 more sources

Update on human papilloma virus - part I: epidemiology, pathogenesis, and clinical spectrum,, [PDF]

Anais Brasileiros de Dermatologia, 2021
Infection with human papilloma virus (HPV) is related to a great number of cutaneous and mucosal manifestations. The spectrum of HPV ranges from inapparent infections, through various clinical benign presentations including cutaneous and mucosal disease,
Geraldo Magela Magalhães, Érica Cristina Vieira, Lucas Campos Garcia, Maria de Lourdes Ribeiro De Carvalho-Leite, Antônio Carlos Martins Guedes, Marcelo Grossi Araújo   +5 more
doaj   +1 more source

Autophagy Modulation by Viral Infections Influences Tumor Development

Frontiers in Oncology, 2021
Autophagy is a self-degradative process important for balancing cellular homeostasis at critical times in development and/or in response to nutrient stress.
Lucas Leonardi, Lucas Leonardi, Sophie Sibéril, Sophie Sibéril, Marco Alifano, Marco Alifano, Isabelle Cremer, Isabelle Cremer, Pierre-Emmanuel Joubert, Pierre-Emmanuel Joubert   +9 more
doaj   +1 more source

Giant anogenital tumor of Buschke–Löwenstein in a patient living with human immunodeficiency virus/acquired immunodeficiency syndrome: a case report

Journal of Medical Case Reports, 2022
Background Buschke–Löwenstein tumor is a giant condyloma acuminata infection that is characterized by degeneration, invasion, and recurrence. It is associated with human papilloma virus infection.
Mathurin Kowo, Jude-Marcel Nzoume Nsope Mengang, Sylvain Raoul Simeni Njonnou, Emmanuel Armand Kouotou, Paul Jean Adrien Atangana, Firmin Ankouane Andoulo   +5 more
doaj   +1 more source

Number of Virus Particles in Insects and Plants Infected with Wound Tumor Virus [PDF]

Journal of Virology, 1968
A new procedure for counting virus particles was employed to measure the concentration of wound tumor virus in purified virus preparations, in plant tumors, and in the insect vector. Partially purified wound tumor virus was used to establish the quantitative features of the method. A 1-g amount of plant tumor tissue contained an average of
G, Streissle, V, Bystricky, R R, Granados, K, Strohmaier   +3 more
openaire   +2 more sources

Virus infections in tumors pave the way for tumor-directed DC-vaccines [PDF]

OncoImmunology, 2012
Effective treatment of solid cancers by tumor-directed DC-vaccines still remains a challenge in clinical oncology. For therapeutic success, knock-down of tumor-specific tolerance appears mandatory before a potent tumor-specific cytotoxic T-cell response can be triggered by DC-vaccinations.
Woller, Norman, Kühnel, Florian, Kubicka, Stefan   +2 more
openaire   +2 more sources

The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy

Cells, 2022
Neutrophils are innate leukocytes with diverse effector functions that allow them to respond to pathogens rapidly. Accumulating evidence has highlighted these cells’ complex roles in the host’s response to viral infections and tumor progression ...
Jessica A. Minott, Jacob P. van Vloten, Lily Chan, Yeganeh Mehrani, Byram W. Bridle, Khalil Karimi   +5 more
doaj   +1 more source

Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H

Viruses, 2021
The coxsackievirus B3 strain PD-0 has been proposed as a new oncolytic virus for the treatment of colorectal carcinoma. Here, we generated a cDNA clone of PD-0 and analyzed the virus PD-H, newly generated from this cDNA, in xenografted and syngenic ...
Ahmet Hazini, Babette Dieringer, Karin Klingel, Markian Pryshliak, Anja Geisler, Dennis Kobelt, Ole Daberkow, Jens Kurreck, Sophie van Linthout, Henry Fechner   +9 more
doaj   +1 more source