Results 31 to 40 of about 97,107 (209)
BackgroundProgrammed cell death protein 1 (PD-1) can attenuate chimeric antigen receptor-T (CAR-T) cell-mediated anti-tumoral immune responses. In this regard, co-administration of anti-PD-1 with CAR-T cells and PD-1 gene-editing of CAR-T cells have been
Mahdi Abdoli Shadbad +15 more
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A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
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Silence of Hippo Pathway Associates with Pro-Tumoral Immunosuppression: Potential Therapeutic Target of Glioblastomas [PDF]
The critical role of the Hippo pathway has been recently investigated in various cancers, but little is known about its role in glioblastoma (GBM).
강석구, 김의현
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Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses.
Deblina Raychaudhuri +14 more
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Conventional and new proposals of GnRH therapy for ovarian, breast, and prostatic cancers
For many years, luteinizing hormone-releasing hormone or gonadotropin-releasing hormone (GnRH) analogs have been used to treat androgen or estrogen-dependent tumors.
Maritza P. Garrido +7 more
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Abdul Al-Farsi, Ayman Al-Talib
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Antimitotic and cytotoxic activity of climacostol on tumoral mammalian cells.
The freshwater ciliate Climacostomum virens defends itself against predators by discharging the toxin climacostol (1,3-dihydroxy-5-[(Z)-20-nonenyl]benzene), a resorcinolic lipid contained in its extrusomes (Miyake et al. 2003, Eur. J. Protistol.
BUONANNO F +3 more
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HLA-G1 increases the radiosensitivity of human tumoral cells [PDF]
Different molecules regulate the response of tumoral tissues to ionizing radiation. The objective of this work was to determine if HLA-G1 expression modulates the radiosensitivity of human tumoral cell lines.
Severino Michelin +11 more
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Stem cells possess two basic characteristics: they are able to renew themselves and to develop into different cell types. The link between normal stem cells and tumor cells could be examined in three aspects: what are the differences and similarities in the control of self-renewal capacity between stem cells and tumor cells; whether tumor cells arise ...
László, Kopper, Melinda, Hajdú
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Sepsis-induced immune dysfunctions are likely to impact on malignant tumor growth. Sequential sepsis-then-cancer models of tumor transplantation in mice recovering from sepsis have shown that the post-septic immunosuppressive environment was able to ...
Clara Vigneron +9 more
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