Results 21 to 30 of about 155,806 (387)

RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing

Oncogene, 2021
The prognosis for patients with metastatic bladder cancer (BCa) is poor, and it is not improved by current treatments. RNA-binding motif protein X-linked (RBMX) are involved in the regulation of the malignant progression of various tumors.
Qiuxia Yan, P. Zeng, Xiu-qin Zhou, Xiaoying Zhao, Runqiang Chen, Jing Qiao, Ling Feng, Zhenjie Zhu, Guozhi Zhang, Cairong Chen   +9 more
semanticscholar   +1 more source

Neural induction drives body axis formation during embryogenesis, but a neural induction-like process drives tumorigenesis in postnatal animals

Frontiers in Cell and Developmental Biology, 2023
Characterization of cancer cells and neural stem cells indicates that tumorigenicity and pluripotency are coupled cell properties determined by neural stemness, and tumorigenesis represents a process of progressive loss of original cell identity and gain
Ying Cao, Ying Cao, Ying Cao
doaj   +1 more source

A comprehensive review on miR-153: Mechanistic and controversial roles of miR-153 in tumorigenicity of cancer cells

Frontiers in Oncology, 2022
miRNAs play a crucial role in regulating genes involved in cancer progression. Recently, miR-153 has been mainly well-known as a tumor suppressive miRNA modulating genes in proliferation, metastasis, EMT, angiogenesis and drug resistance ability of a ...
Saghar Yousefnia
doaj   +1 more source

Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic Strategies

Cells, 2020
Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to resistance to traditional treatments and tumor recurrence after therapy, which leads to poor therapeutic outcomes.
Yu-Chin Liu, Chau-Ting Yeh, Kwang-Huei Lin   +2 more
doaj   +1 more source

Knockout of ENO1 leads to metabolism reprogramming and tumor retardation in pancreatic cancer

Frontiers in Oncology, 2023
The shift in glucose utilization from oxidative phosphorylation to glycolysis is the hallmark of tumor cells. The overexpression of ENO1, one of the key enzymes in the glycolysis process, has been identified in several cancers, however, its role in ...
Qingru Song, Kai Zhang, Tianjiao Sun, Congcong Xu, Wei Zhao, Zhiqian Zhang   +5 more
doaj   +1 more source

Vortioxetine induces apoptosis and autophagy of gastric cancer AGS cells via the PI3K/AKT pathway

FEBS Open Bio, 2020
Vortioxetine is a potent antagonist of the 5‐hydroxytryptamine receptor and serotonin transporter and has been reported to function as an antidepressant in the treatment of major depressive disorder. However, its antitumor effects remain unclear.
Gao‐Bo Lv, Ting‐Ting Wang, Hai‐Lin Zhu, Hong‐Ke Wang, Wen Sun, Li‐Feng Zhao   +5 more
doaj   +1 more source

Matrix metalloproteinases-2,-3,-7,-9 and-10, but not MMP-11, are differentially expressed in normal, benign tumorigenic and malignant human keratinocyte cell lines [PDF]

, 2000
In order to investigate the correlations between constitutive proteinase expression and the degree of tumorigenicity of cancer cells we have studied a model system of three keratinocyte cell lines.
Bachmeier, B. E., Boukamp, P., Fink, E., Fusenig, N. E., Lichtinghagen, R.   +4 more
core   +1 more source

HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis [PDF]

, 2018
Cytokinesis, the final phase of cell division, is necessary to form two distinct daughter cells with correct distribution of genomic and cytoplasmic materials.
A Konishi, A Verdina, AC Borisa, AT Lau, B Mierzwa, C Ditchfield, C Lazzari, C Mollinari, C Norden, C Rinaldo, C Rinaldo, C Rinaldo, C Rinaldo, Cinzia Rinaldo, CK Hu, D Valente, Davide Valente, E Gresko, F Siepi, G D’Orazi, G D’Orazi, G Normand, GE Atilla-Gokcumen, H Goto, HC Huang, I Vitale, JA Blaquiere, JM Cummins, JP Fededa, JR Bischoff, K Kobiyama, L Vega De la, Laura Monteonofrio, M Agromayor, M Carmena, M Glotzer, M Kollareddy, Manuela Ferrara, Marco Crescenzi, ME Douglas, ME Douglas, O Afonso, P Carpinelli, PP D’Avino, R Kuriyama, R Nunes Bastos, Roberta Miscione, S Francia, S Hauf, S Matt, Serena Camerini, Silvia Soddu, SM Lens, TD Pollard, TG Hofmann, TG Hofmann, V Bavetsias, VV Saul, VV Saul, WM Zhao, XL Li, Y Feng, Y Kuwano, Y Terada, YH Kim, Z Storchova   +65 more
core   +1 more source

The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma

Biology, 2022
(1) Background: The functions of the tropomyosin (TPM) family in tumors and cancers have been explored; however, striking differences have been observed.
Ke Huang, Huihui Wang, Jia Xu, Ruiming Xu, Zelin Liu, Yi Li, Zhaoqing Xu   +6 more
doaj   +1 more source

Tumorigenicity of EBNA2‐transfected cells [PDF]

FEBS Letters, 1995
The Epstein‐Barr virus nuclear antigen 2 (EBNA2) gene is thought to be important for transformation by Epstein‐Barr virus (EBV), but the mechanism of this transformation is little understood. Here, to examine the transforming ability of EBNA2, we transfected a rat fibroblast cell line F2408 with a recombinant EBNA2 expression plasmid and examined cell ...
M, Shimakage, A, Kurata, H, Inoue, Y, Okamoto, M, Yutsudo, A, Hakura   +5 more
openaire   +2 more sources