Results 41 to 50 of about 7,025 (165)

Hegel's Theory of Absolute Spirit. Reflexive Practices in Hegel's Social Philosophy

European Journal of Philosophy, EarlyView.
Abstract This paper argues that Hegel's concept of absolute spirit should be understood as central to his social philosophy. Rather than designating a metaphysical endpoint, absolute spirit refers to reflexive practices—art, religion, and philosophy—through which societies critically engage with the norms and assumptions that structure social life ...
Markus Gante
wiley   +1 more source

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Meta-imputation of transcriptome from genotypes across multiple datasets by leveraging publicly available summary-level data.

PLoS Genetics, 2022
Transcriptome wide association studies (TWAS) can be used as a powerful method to identify and interpret the underlying biological mechanisms behind GWAS by mapping gene expression levels with phenotypes.
Andrew E Liu, Hyun Min Kang
doaj   +1 more source

TIGAR-V2: Efficient TWAS tool with nonparametric Bayesian eQTL weights of 49 tissue types from GTEx V8

HGG Advances, 2022
Summary: Standard transcriptome-wide association study (TWAS) methods first train gene expression prediction models using reference transcriptomic data and then test the association between the predicted genetically regulated gene expression and ...
Randy L. Parrish, Greg C. Gibson, Michael P. Epstein, Jingjing Yang   +3 more
doaj   +1 more source

Trauma, sociogenesis, and the work of societal healing after conflict: “All Rwandans are wounded”

Ethos, EarlyView.
Abstract This article explores recurring problems in post‐conflict studies of trauma through the lens of evolving discourses of psychic woundedness in post‐genocide Rwanda. Research suggests that global psychiatric discourses did not enter the Rwandan public sphere until after the 1994 Genocide Against the Tutsi, at which point local iterations of ...
Zoë Elizabeth Berman
wiley   +1 more source

On the Move to Surgery: A Scoping Review of Patient‐Reported Outcomes for Preoperative Walking Into the Operating Theatre

Journal of Advanced Nursing, EarlyView.
ABSTRACT Introduction Although healthcare infrastructure has improved in recent years, the preoperative journey of patients is often accompanied by anxiety. Allowing patients to walk to the operating theatre is a simple, yet underexplored strategy that may enhance their sense of autonomy and reduce anxiety.
Sebastian Labenbacher, Sascha Hammer, Angelika Moser, Nikolaus Schreiber, Helmar Bornemann‐Cimenti   +4 more
wiley   +1 more source

Multiple-Tissue Integrative Transcriptome-Wide Association Studies Discovered New Genes Associated With Amyotrophic Lateral Sclerosis

Frontiers in Genetics, 2020
Genome-wide association studies (GWAS) have identified multiple causal genes associated with amyotrophic lateral sclerosis (ALS); however, the genetic architecture of ALS remains completely unknown and a large number of causal genes have yet been ...
Lishun Xiao, Zhongshang Yuan, Siyi Jin, Ting Wang, Shuiping Huang, Shuiping Huang, Ping Zeng, Ping Zeng   +7 more
doaj   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

Orthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei, Chang Liu, Shanlin Chen, Min Liu   +3 more
wiley   +1 more source

Detection of H$_2$ in the TWA 7 System: A Probable Circumstellar Origin [PDF]

, 2021
Laura Flagg, Christopher M. Johns‐Krull, Gregory J. Herczeg, Joan Najita, John Carptenter, Scott J. Kenyon   +5 more
openalex   +1 more source

The fettered and the flea: a new poem by Edmund Waller☆

Renaissance Studies, EarlyView.
Abstract This contribution explores for the first time a 22‐line poem in a British Library manuscript, ‘To a young lady that kept a flea chay'nd in a box’, which can be convincingly ascribed to Edmund Waller. Its most famous relative is Donne's ‘The Flea’, but its ancestry differs.
Stuart Gillespie
wiley   +1 more source