Results 51 to 60 of about 7,025 (165)

Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate

open access: yesiScience, 2020
Summary: Most genome-wide association studies (GWAS) and transcriptome-wide association studies (TWAS) focus on European populations; however, these results cannot always be accurately applied to non-European populations due to genetic architecture ...
Elyse Geoffroy   +2 more
doaj   +1 more source

From Everyman to Hamlet: A Distant Reading

open access: yesRenaissance Studies, EarlyView.
Abstract The sixteenth century sees English drama move from Everyman to Hamlet: from religious to secular subject matter and from personified abstractions to characters bearing proper names. Most modern scholarship has explained this transformation in terms originating in the work of Jacob Burckhardt: concern with religion and a taste for ...
Vladimir Brljak
wiley   +1 more source

Multi‐Omics‐Augmented GWAS for Crop Improvement: From Mechanisms to Breeding

open access: yesModern Agriculture, Volume 3, Issue 2, December 2025.
This review presents an integrated framework that synergises multi‐omics with GWAS and machine learning to decode the genetic basis of complex agronomic traits, bridging biological discovery to precision breeding for climate‐resilient crops. ABSTRACT Global food security demands innovative strategies to enhance crop resilience and productivity amidst ...
Naimatullah Mangi   +17 more
wiley   +1 more source

Transcriptome-Wide Association Supplements Genome-Wide Association in Zea mays

open access: yesG3: Genes, Genomes, Genetics, 2019
Modern improvement of complex traits in agricultural species relies on successful associations of heritable molecular variation with observable phenotypes. Historically, this pursuit has primarily been based on easily measurable genetic markers.
Karl A. G. Kremling   +4 more
doaj   +1 more source

Lawnmower Poetry and the Poetry of Lawnmowers

open access: yes
Critical Quarterly, EarlyView.
Francesca Gardner
wiley   +1 more source

Marker Metabolite‐Based Multi‐Omics Analysis Identifies New Loci Controlling Thousand Seed Weight in Brassica Napus

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
Marker metabolite‐based multi‐omics (genome, transcriptome, and metabolome) analysis is conducted firstly to unravel the genetic basis of thousand seed weight (TSW) in Brassica napus. The released metabolite‐QTL‐gene network represents a valuable genetic resource, and the newly validated BnaTGA6 is a promising target for the improvement of TSW in ...
Long Li   +10 more
wiley   +1 more source

MAAT: a new nonparametric Bayesian framework for incorporating multiple functional annotations in transcriptome-wide association studies

open access: yesGenome Biology
Transcriptome-wide association study (TWAS) has emerged as a powerful tool for translating the myriad variations identified by genome-wide association studies (GWAS) into regulated genes in the post-GWAS era.
Han Wang   +5 more
doaj   +1 more source

Critical Assessment of the Recommended Alert Limit Curves for Occupational Heat Exposure

open access: yesAmerican Journal of Industrial Medicine, Volume 68, Issue 11, Page 1004-1012, November 2025.
ABSTRACT Background Occupational heat stress recommendations aim to achieve thermal equilibrium and keep core temperature (Tc) below 38.0°C. We assessed the recommended alert limit curves when: (1) work–rest ratios are adjusted based on wet‐bulb globe temperature (WBGT) at a fixed rate of metabolic heat production (Hprod) and (2) Hprod is adjusted ...
Hayden W. Hess   +7 more
wiley   +1 more source

Integrative multi‐omics approaches identify molecular pathways and improve Alzheimer's disease risk prediction

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is a complex neurodegenerative disorder with heterogeneous genetic and molecular underpinnings. Polygenic scores (PGS) capture little of this complexity. METHODS We conducted genome‐, transcriptome‐, and proteome‐wide association studies (G/T/PWAS) on 15,480 individuals from the Alzheimer's Disease ...
Rasika Venkatesh   +8 more
wiley   +1 more source

Phenotyping stomatal closure by thermal imaging for GWAS and TWAS of water use efficiency-related genes [PDF]

open access: bronze, 2021
Charles P. Pignon   +9 more
openalex   +1 more source

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