Results 61 to 70 of about 19,781 (230)

Analysis of the Influence of Process and Formulation Properties on the Drying Behavior of Pharmaceutical Granules in a Semi-Continuous Fluid Bed Drying System

Powders, 2023
In the last decade, twin-screw wet granulation became an essential technology for continuous pharmaceutical tablet production. Consequently, interest in (semi-)continuous fluidized bed drying systems as a subsequent processing unit has grown. In parallel,
Tuur Vandeputte, Michael Ghijs, Michiel Peeters, Alexander De Man, Daan Van Hauwermeiren, Eduardo Dos Santos Schultz, Tamas Vigh, Fanny Stauffer, Ingmar Nopens, Thomas De Beer   +9 more
doaj   +1 more source

Pellet Printing for Soft Robotic Devices

Advanced Science, EarlyView.
Fused Granulate Fabrication (FGF) is established here as a reliable method for fabricating soft, airtight robotic devices. Through coordinated optimization of hardware, material selection, and process parameters, this approach enables high‐speed printing of thermoplastic elastomers with silicone‐like softness and modulus.
Yijia Wu, Ju‐Hung Chen, Ariana Olivares, Katherine Kostak, Stefan Pedicone, Savita V. Kendre, Markus P. Nemitz   +6 more
wiley   +1 more source

Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs

Pharmaceutics, 2023
The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach.
Dinesh Nyavanandi, Preethi Mandati, Sagar Narala, Abdullah Alzahrani, Praveen Kolimi, Sateesh Kumar Vemula, Michael A. Repka   +6 more
doaj   +1 more source

Continuous manufacturing via hot-melt extrusion and scale up: regulatory matters [PDF]

, 2017
Currently, because globalization, the pharmaceutical industry is facing enormous challenges to comply with regulatory matters. Reduced patent life and overall decreased profitability of newly discovered drugs are also forcing the pharmaceutical industry ...
Abboud, Al-Asady, Ali Nokhodchi, Anderson, Anon, Anon, Anon, Anon, Baumgartner, Berzin, Breitenbach, Bryn, Cannon, Carneiro, Chan, Crowley, Dalziel, Dalziel, Damir, Dimasi, Dimasi, Dong, Fonteyne, Fule, Ganjyal, Grycze, Guy, Hossain, Islam, Islam, Jones, Keen, Kelly, Kossik, Krier, Kumar, Lang, Li, Li, Listro, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Maniruzzaman, Meier, Meyer, Mohammed Maniruzzaman, Mollan, Moradiya, Muehlenfeld, Nowak, Omar, Ozen, Patil, Patil, Paulsen, Proctor, Proctor, Rawendaal, Reitz, Repka, Repka, Repka, Repka, Rouni, Saerens, Sayin, Todd, Todd, Todd, US FDA Center for Drug Evaluation and Research, US FDA Center for Drug Evaluation and Research, US FDA Center for Drug Evaluation and Research, Vercruysse, Vercruysse, Vithani, Wahl, White, Wold, Zhang   +86 more
core   +1 more source

An interpretable fuzzy logic based data-driven model for the twin screw granulation process

Powder Technology, 2020
In this research, a new framework based on fuzzy logic is proposed to model the twin screw granulation (TSG) process. First, various fuzzy logic systems (FLSs) having different structures are developed to define various rule bases.
Wafa’ H. Alalaween, Bilal Khorsheed, M. Mahfouf, G. Reynolds, A. Salman   +4 more
semanticscholar   +1 more source

Tailored granule properties using 3D printed screw geometries in twin screw granulation [PDF]

Powder Technology, 2019
Twin screw granulation is becoming increasingly relevant due to its compact size, continuous and robust mode of operation, customizable design, and flexible production capacity. This work describes the experimental study undertaken to understand the dependence of granule properties on the screw element design in a twin screw granulator.
Pradhan, S.U., Zhang, Y., Li, J., Litster, J.D, Wassgren, C.R   +4 more
openaire   +1 more source

Design‐Driven Production of Soybean Oil‐Based Structured Fats as Potential Substitutes for Palm‐Based Fats

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT This study examined whether enzymatic modification of soybean oil (SBO) can be tailored to produce trans‐free fats with physicochemical properties comparable to palm olein, stearin, or palm‐mid fractions (PMFs). US‐grown SBO was modified by lipase‐catalyzed acidolysis using palmitic acid at linearly interpolated substrate molar ratios (C16:0 ...
Ityotagher P. Aondoakaa, Silvana Martini, Casimir C. Akoh   +2 more
wiley   +1 more source

The Influence of Equipment Design and Process Parameters on Granule Breakage in a Semi-Continuous Fluid Bed Dryer after Continuous Twin-Screw Wet Granulation

Pharmaceutics, 2021
The drying unit of a continuous from-powder-to-tablet manufacturing line based on twin-screw granulation (TSG) is a crucial intermediate process step to achieve the desired tablet quality.
Alexander Ryckaert, Michael Ghijs, Christoph Portier, Dejan Djuric, Adrian Funke, Chris Vervaet, Thomas De Beer   +6 more
doaj   +1 more source

Development and Characterization of ZnO‐Filled and Maleic Anhydride‐Compatibilized PP/SEBS Blends for 3D‐Printing Filaments

Journal of Applied Polymer Science, EarlyView.
PP/SEBS/MA/ZnO filaments produced by bench‐top single‐screw extrusion show refined morphology, increased crystallinity, improved thermal robustness, and preliminary FFF printability, demonstrating a practical route for functional filament development. ABSTRACT Currently, single‐screw extrusion offers a versatile and accessible route to produce polymer ...
Chiara das Dores do Nascimento, Cesar Aguzzoli, Everton Granemann Souza, Ana Cristina Beitia Kraemer Moraes, Fabricio Celso, Patricia Oliveira Schmitt, Lincoln Audrew Cordeiro, Fernanda Langone, Marlon Bender Bueno Rodrigues, Luana Vaz Tholozan, Neftali Lenin Villarreal Carreno, André Luiz Missio, Amanda Dantas de Oliveira   +12 more
wiley   +1 more source

Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan, E. Svaluto‐Ferro, N. Kovalska, G. Graeber, F. Vagliani, D. Basso, A. Turconi, M. Makowska, G. Blugan, C. Battaglia, M. V. F. Heinz   +10 more
wiley   +1 more source