Results 101 to 110 of about 22,249 (182)
Yebei Qiu,1,2,* Xiaocheng Cao,1,2,* Lihua Liu,3,4 Xiaozheng Cao,3,4 Qing Yuan,5 Xiang Li,5 Yinghong Cui,1,5 Chang Xu,1,2 Chang Zou,4,6 Kaiqun Ren,1,2 Jianguo Cao1,2 1The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Medical ...
Qiu Y +10 more
doaj
Comparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Natalia Platonova +13 more
wiley +1 more source
Investigating the role of TWIST1 in medulloblastoma metastasis [PDF]
Introduction Medulloblastoma is the most common malignant paediatric brain tumour. Many patients present with metastatic disease and sadly this remains a powerful predictor for poor outcome.
Cardall, Alice
core
Twist1- and Twist2-haploinsufficiency results in reduced bone formation. [PDF]
Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to inhibit osteogenesis, only Twist1 haploinsufficiency is associated
Suzhen Wang (163752) +27 more
core +2 more sources
Étude in silico et caractérisation fonctionnelle des complexes de TWIST1
Aberrant reactivation embryonic TWIST1 gene has been identified in the laboratory as a recurrent inactivation mechanism dependent pathways of p53 and Rb in many tumors.
Bouard, Charlotte
core +1 more source
Role of Twist1 transcription factor in thyroid tumor progression [PDF]
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core +1 more source
In silico study and functional characterization of TWIST1 complex
La réactivation aberrante du gène TWIST1 embryonnaire a été identifiée dans le laboratoire comme un mécanisme d'inactivation récurrente des voies dépendantes de p53 et Rb dans de nombreuses tumeurs. En diminuant la sénescence et l’induction de l'apoptose,
Bouard, Charlotte
core
Twist1 promotes tumor initiation in vivo.
Transgene expression was driven by WAP-Cre. While WAP-Cre;Twist1 (TWIST1; n = 25) and WAP-Cre;K-RasG12D (RAS; n = 19) mice remained healthy, WAP-Cre;K-RasG12D;Twist1 females (RAS+TWIST1; n = 21) developed metaplastic mammary carcinomas.
Anne Wierinckx (164065) +16 more
core +1 more source
Abstract 3402: Knockdown of TWIST1 increases chemosensitivity of osteosarcoma cells
Knock-down of TWIST1 increases chemosensitivity of osteosarcoma cells Texas Children's Cancer Center; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 TWIST1, a basic helix-loop-helix ...
Gufeng Xu +5 more
core +1 more source
Background: Lung cancer is the leading cause of cancer-related mortality worldwide, and metastasis is the key factor leading to patient death.
Wenying Wang, Liang Zhang, Ping Wang
doaj +1 more source

