Results 101 to 110 of about 29,018 (198)

New insights into the crossroads between EMT and stemness in the context of cancer [PDF]

, 2016
The epithelial-mesenchymal transition (EMT) is an example of cellular plasticity, where an epithelial cell acquires a mesenchymal-like phenotype that increases its migratory and invasive properties. Stemness is the ability of stem cells to proliferate in
Fabregat Romero, Isabel, Malfettone, Andrea, Soukupova, Jitka   +2 more
core   +1 more source

Twist1 promotes astrocytoma development by stimulating vasculogenic mimicry

Oncology Letters, 2019
Astrocytomas are one of the most vascularized types tumor in human cancers. Micro-vascular proliferation is an important factor for the classification of astrocytoma. Vasculogenic mimicry (VM) is a novel tumor vascular model that develops independently of endothelial cells, and serves an important role in astrocytoma.
Wei, Cao, Can, Xu, Xinxing, Li, Xianghong, Yang   +3 more
openaire   +3 more sources

The role of hypoxia in glioblastoma invasion [PDF]

, 2017
Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 to 17 months. The current treatment for GBM involves tumor resection surgery
Frederick, Huss, Kivelä, Malden, Ravi, Rempel, Stracke, Yuan, Zhong   +8 more
core   +3 more sources

MicroRNAs and epithelial-mesenchymal transition in prostate cancer. [PDF]

, 2016
Prostate cancer (PCa) is a leading cause of male cancer-related deaths. A significant fraction of prostate tumors are very aggressive, often metastasizing to bone, causing significant morbidity and mortality.
Bucay, Nathan, Dahiya, Rajvir, Majid, Shahana, Saini, Sharanjot, Sekhon, Kirandeep   +4 more
core   +1 more source

TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis

Cancer Cell International
Objective TWIST1 is known to promote glycolysis and contribute to pancreatic cancer development; however, its underlying mechanisms remain poorly understood.
Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang   +6 more
doaj   +1 more source

Elucidating the role of TWIST1 in ulcerative colitis: a comprehensive bioinformatics and machine learning approach

Frontiers in Genetics
Background: Ulcerative colitis (UC) is a common and progressive inflammatory bowel disease primarily affecting the colon and rectum. Prolonged inflammation can lead to colitis-associated colorectal cancer (CAC).
Wenjie Ou, Zhaoxue Qi, Ning Liu, Junzi Zhang, Xuguang Mi, Yuan Song, Yanqiu Fang, Baiying Cui, Junjie Hou, Zhixin Yuan   +9 more
doaj   +1 more source

Review: Carbon Nanotubes and Chronic Granulomatous Disease [PDF]

, 2014
Use of nanomaterials in manufactured consumer products is a rapidly expanding industry and potential toxicities are just beginning to be explored.
Bardinas, Bergeron, Chensue, Crouser, Gerdes, Ghossein, Ishige, Iyonaga, Izbicki, Judson, Judson, Kunkel, Lam, Mercer, O’Regan, Perez, Petersen, Rybicki, Ryman-Rasmussen, Song, Staal, Wu   +21 more
core   +2 more sources

Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells

Cancer Management and Research, 2020
Yebei Qiu,1,2,* Xiaocheng Cao,1,2,* Lihua Liu,3,4 Xiaozheng Cao,3,4 Qing Yuan,5 Xiang Li,5 Yinghong Cui,1,5 Chang Xu,1,2 Chang Zou,4,6 Kaiqun Ren,1,2 Jianguo Cao1,2 1The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Medical ...
Qiu Y, Cao X, Liu L, Cao X, Yuan Q, Li X, Cui Y, Xu C, Zou C, Ren K, Cao J   +10 more
doaj  

Multiple biological functions of Twist1 in various cancers

Oncotarget, 2017
Twist1 is a well-known regulator of transcription during embryonic organogenesis in many species. In humans, Twist1 malfunction was first linked to Saethre-Chotzen syndrome and later identified to play an essential role in tumor initiation, stemness, angiogenesis, invasion, metastasis, and chemo-resistance in a variety of carcinomas, sarcomas, and ...
Zhao, Zhixiang, Rahman, Mohammad Aminur, Chen, Zhuo G., Shin, Dong M.   +3 more
openaire   +3 more sources

Twisted K-homology,Geometric cycles and T-duality [PDF]

, 2014
Twisted $K$-homology corresponds to $D$-branes in string theory. In this paper we compare two different models of geometric twisted $K$-homology and get their equivalence.
Liu, Bei
core