Results 121 to 130 of about 28,841 (200)

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G, Corvalan, AH, Owen, GI, Pinto, MP, Sotomayor, P   +4 more
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis

Cancer Cell International
Objective TWIST1 is known to promote glycolysis and contribute to pancreatic cancer development; however, its underlying mechanisms remain poorly understood.
Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang   +6 more
doaj   +1 more source

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

Molecular Cancer, 2010
Background Tumor cell invasion into adjacent normal brain is a mesenchymal feature of GBM and a major factor contributing to their dismal outcomes.
Wakimoto Hiroaki, Glackin Carlotta A, Maxwell John-Patrick, Oxford Robert G, Khorasani Leila, Beyer Richard, Petit Audrey, Mikheev Andrei M, Mikheeva Svetlana A, González-Herrero Inés, Sánchez-García Isidro, Silber John R, Horner Philip J, Rostomily Robert C   +13 more
doaj   +1 more source

Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells

Cancer Management and Research, 2020
Yebei Qiu,1,2,* Xiaocheng Cao,1,2,* Lihua Liu,3,4 Xiaozheng Cao,3,4 Qing Yuan,5 Xiang Li,5 Yinghong Cui,1,5 Chang Xu,1,2 Chang Zou,4,6 Kaiqun Ren,1,2 Jianguo Cao1,2 1The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Medical ...
Qiu Y, Cao X, Liu L, Cao X, Yuan Q, Li X, Cui Y, Xu C, Zou C, Ren K, Cao J   +10 more
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Multiple biological functions of Twist1 in various cancers

Oncotarget, 2017
Twist1 is a well-known regulator of transcription during embryonic organogenesis in many species. In humans, Twist1 malfunction was first linked to Saethre-Chotzen syndrome and later identified to play an essential role in tumor initiation, stemness, angiogenesis, invasion, metastasis, and chemo-resistance in a variety of carcinomas, sarcomas, and ...
Zhao, Zhixiang, Rahman, Mohammad Aminur, Chen, Zhuo G., Shin, Dong M.   +3 more
openaire   +3 more sources

FOXD3 Regulates VISTA Expression in Melanoma. [PDF]

, 2020
Immune checkpoint inhibitors have improved patient survival in melanoma, but the innate resistance of many patients necessitates the investigation of alternative immune targets.
Aplin, Andrew E., Berger, Adam C., Chervoneva,, Davies, Michael A., Erkes, Dan A., Fisher, David E., Gershenwald, Jeffrey E., Knecht, Meghan, Lo, Jennifer A., McCue, Peter A., Mollaee, Mehri, Purwin, Timothy J., Rosenbaum, Sheera R., Zhong, Zhijiu   +13 more
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Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

Data in Brief, 2016
This article contains data related to the research article entitled “Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance” by Bildsoe et al. (2016) [1]. The data presented here are derived
Heidi Bildsoe, Xiaochen Fan, Emilie E. Wilkie, Ator Ashoti, Vanessa J. Jones, Melinda Power, Jing Qin, Junwen Wang, Patrick P.L. Tam, David A.F. Loebel   +9 more
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Elucidating the role of TWIST1 in ulcerative colitis: a comprehensive bioinformatics and machine learning approach

Frontiers in Genetics
Background: Ulcerative colitis (UC) is a common and progressive inflammatory bowel disease primarily affecting the colon and rectum. Prolonged inflammation can lead to colitis-associated colorectal cancer (CAC).
Wenjie Ou, Zhaoxue Qi, Ning Liu, Junzi Zhang, Xuguang Mi, Yuan Song, Yanqiu Fang, Baiying Cui, Junjie Hou, Zhixin Yuan   +9 more
doaj   +1 more source

TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production

BMC Biology, 2012
Background Metastasis is the primary cause of death for cancer patients. TWIST1, an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor, is a strong promoter of metastatic spread and its expression is elevated in many advanced ...
Li Shan, Kendall Stephen E, Raices Raquel, Finlay James, Covarrubias Maricela, Liu Zheng, Lowe Gina, Lin Yu-Huey, Teh Yuan, Leigh Victoria, Dhillon Simi, Flanagan Steven, Aboody Karen S, Glackin Carlotta A   +13 more
doaj   +1 more source

Variants in Hdac9 Intronic Enhancer as Candidates for Skin Tumor Susceptibility Locus [PDF]

, 2014
Health Professions - Laboratory/Cellular: 3rd Place (The Ohio State University Denman Undergraduate Research Forum)Non-melanoma skin cancers (NMSC) are the most common forms of cancer in the world accounting for nearly half of all cancer diagnoses. Rates
Siekmann, Tyler
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