Results 191 to 200 of about 28,841 (200)

TWIST1 upregulates the MAGEA4 oncogene

Molecular Carcinogenesis, 2016
Overexpression of MAGEA4 oncogene has been demonstrated in different malignancies; however, little is known about its exact mechanism for overexpression. TWIST1, as a bHLH transcription factor, activates a cell migration‐invasion program involved in both embryonic and tumor development. Since MAGEA4 overexpression was statistically correlated to TWIST1,
Mohammad Mahdi, Forghanifard, Abolfazl, Rad, Moein, Farshchian, Maryam, Khaleghizadeh, Mehran, Gholamin, Meysam, Moghbeli, Mohammad Reza, Abbaszadegan   +6 more
openaire   +2 more sources

Twist1 promotes dendritic cell-mediated antitumor immunity

Experimental Cell Research, 2020
Dendritic cells (DCs) play a central role in autoimmunity, immune homeostasis, and presentation of tumor antigens to T cells in order to prime antitumor responses. The number of tumor-infiltrating DCs is associated with survival and prognosis in cancer.
Yuechen, Luo, Jiadi, Chen, Maolan, Liu, Song, Chen, Xiuhua, Su, Jing, Su, Chunxiao, Zhao, Zhongchao, Han, Mingxia, Shi, Xiaotong, Ma, Huifang, Huang   +10 more
openaire   +2 more sources

Targeting epithelial cell-derived TWIST1 alleviates allergic asthma

Cellular Signalling, 2023
It is well known that the T Helper (Th)2 bias plays a critical role in allergic asthma. Whereas the Th2 bias is maintained in the local tissues is uncertain. IL-33 is vital for the development of the Th2 polarization. TWIST-1 has an effect on regulating cellular functions. The aberrant activation of RAS sustains certain cellular activities.
Huanping, Zhang, Yanfen, Wang, Xiaoxue, Chen, Aizhi, Zhang, Lijun, Hou, Jingyi, Hong, Jiangqi, Liu, Zhiqiang, Liu, Pingchang, Yang   +8 more
openaire   +2 more sources

RAC1 activation mediates Twist1-induced cancer cell migration

Nature Cell Biology, 2012
Epithelial-mesenchymal transition (EMT), which is characterized by the suppression of the adhesion protein E-cadherin, is a crucial process that promotes metastasis and stem-like properties of cancer cells. However, the dissociation of cellular aggregates is not sufficient to explain why cancer cells move, and the motile nature of cancer cells ...
Wen-Hao, Yang, Hsin-Yi, Lan, Chi-Hung, Huang, Shyh-Kuan, Tai, Cheng-Hwai, Tzeng, Shou-Yen, Kao, Kou-Juey, Wu, Mien-Chie, Hung, Muh-Hwa, Yang   +8 more
openaire   +2 more sources

Emerging biological functions of Twist1 in cell differentiation

Developmental Dynamics
AbstractTwist1 is required for embryonic development and expresses after birth in mesenchymal stem cells derived from mesoderm, where it governs mesenchymal cell development. As a well‐known regulator of epithelial–mesenchymal transition or embryonic organogenesis, Twist1 is important in a variety of developmental systems, including mesoderm formation,
Mengjie Tu, Bingqian Ge, Jiali Li, Yanbing Pan, Binbin Zhao, Jiayang Han, Jialin Wu, Kaifeng Zhang, Guangchao Liu, Mengwen Hou, Man Yue, Xu Han, Tiantian Sun, Yang An   +13 more
openaire   +2 more sources

575: The oncogenic potential of TWIST1 is specifically assigned to the TWIST1-E2A complex

European Journal of Cancer, 2014
L. Jacqueroud, C. Bouard, A. Tissier, G. Richard, L. Payen-Gay, J. Caramel, A. Puisieux, S. Ansieau   +7 more
openaire   +1 more source

Control of TWIST1 by NOD2.

openaire   +1 more source

TWIST1 and the Saethre-Chotzen Syndrome

2016
openaire   +1 more source